Dive into the Differentiation of Naive CD4+ T Cells
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Questions and Answers

Which combination of signals drives the differentiation of naive CD4+ T cells to Th1 effector cells?

  • Antigen-induced TCR signaling and IL-12 (correct)
  • IL-12 and IFN-γ
  • Antigen-induced TCR signaling and IFN-γ
  • IL-12 and Type I IFNs
  • Which cells produce IFN-γ in response to many bacteria and viruses?

  • B cells
  • Natural killer (NK) cells (correct)
  • T cells
  • Dendritic cells and macrophages
  • Which transcription factor is essential for Th1 development and function?

  • Stat1
  • IFN-γ
  • Stat4
  • T-bet (correct)
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