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Questions and Answers
Which combination of signals drives the differentiation of naive CD4+ T cells to Th1 effector cells?
Which combination of signals drives the differentiation of naive CD4+ T cells to Th1 effector cells?
- Antigen-induced TCR signaling and IL-12 (correct)
- IL-12 and IFN-γ
- Antigen-induced TCR signaling and IFN-γ
- IL-12 and Type I IFNs
Which cells produce IFN-γ in response to many bacteria and viruses?
Which cells produce IFN-γ in response to many bacteria and viruses?
- B cells
- Natural killer (NK) cells (correct)
- T cells
- Dendritic cells and macrophages
Which transcription factor is essential for Th1 development and function?
Which transcription factor is essential for Th1 development and function?
- Stat1
- IFN-γ
- Stat4
- T-bet (correct)
