3 Questions
Which combination of signals drives the differentiation of naive CD4+ T cells to Th1 effector cells?
Antigen-induced TCR signaling and IL-12
Which cells produce IFN-γ in response to many bacteria and viruses?
Natural killer (NK) cells
Which transcription factor is essential for Th1 development and function?
T-bet
Test your knowledge on the differentiation of naive CD4+ T cells to Th1 effector cells. Learn about the role of T cell receptor signaling, cytokines IL-12 and IFN-γ, and the response to bacteria and viruses.
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