MOL GEN Epigenetic 3: X-Chromosome Inactivation and Dosage Compensation
16 Questions
1 Views

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

In mammals, which mechanism is responsible for balancing gene expression between males and females?

  • Dosage compensation through inactivation of genes
  • X-inactivation through facultative heterochromatin (correct)
  • X-inactivation through constitutive heterochromatin
  • Dosage composition through activation of genes

    • What is the purpose of dosage compensation in gene expression?

  • To deactivate genes on the Y chromosome
  • To increase the expression of genes in females
  • To balance the amount of gene expression between males and females (correct)
  • To decrease the expression of genes in males

    • What is the role of constitutive heterochromatin in mammals?

  • To permanently deactivate gene expression (correct)
  • To permanently activate gene expression
  • To control gene expression only in males
  • To regulate gene expression based on environmental factors

    • In C.Elegans, what leads to the balance in gene expression between males and females?

    <p>Inactivation of genes on one of the X chromosomes in females</p> Signup and view all the answers

    What is the main difference between constitutive heterochromatin and facultative heterochromatin?

    <p>Constitutive heterochromatin permanently deactivates gene expression, while facultative heterochromatin regulates gene expression based on environmental factors</p> Signup and view all the answers

    What is the purpose of X-inactivation in females in Drosophila?

    <p>To balance the amount of X-linked gene expression between males and females</p> Signup and view all the answers

    What is the term for the state where genes are actually present but inactive?

    <p>Facultative heterochromatin</p> Signup and view all the answers

    During X inactivation, what happens to the other X chromosome?

    <p>It becomes a barr body</p> Signup and view all the answers

    What is the term for the region necessary for the inactivation of the X chromosome itself?

    <p>Inactivation center</p> Signup and view all the answers

    What does the Xist gene transcript bind to in the nucleus?

    <p>Future inactive X</p> Signup and view all the answers

    What is the name of the unstable RNA that prevents the binding of the Xist gene transcript to the inactivation center?

    <p>t6</p> Signup and view all the answers

    What is necessary for the recruitment of heterochromatin proteins and formation of heterochromatin?

    <p>Xist gene transcript</p> Signup and view all the answers

    Which type of RNA forms a kind of triplex structure with DNA and binds to its own locus in the nucleus?

    <p>Xist gene transcript</p> Signup and view all the answers

    What is the term for DNA wrapped with protein and RNA to form a more condensed structure?

    <p>Chromatin</p> Signup and view all the answers

    What type of genes escape from X inactivation?

    <p>Active genes</p> Signup and view all the answers

    What happens to determined female characters at the very beginning of embryonic development?

    <p>They become active</p> Signup and view all the answers

    More Like This

    Use Quizgecko on...
    Browser
    Open
    Browser
    Browser