Medicine Dispensing and Calculations
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Questions and Answers

How many grams of salicylic acid should be added to 500g of 10% salicylic acid ointment to achieve a final concentration of 25% salicylic acid?

  • 200 g (correct)
  • 250 g
  • 100 g
  • 150 g
  • What is the final weight in grams of the solution if 5g of a solid ingredient is combined with 45g of a base?

  • 55 g
  • 50 g (correct)
  • 40 g
  • 60 g
  • For a concentrated antiseptic solution containing Chlorhexidine Gluconate and Cetrimide in a 20:1 ratio, how much Cetrimide is in 25 mL if it contains 0.015% w/v Chlorhexidine?

  • 0.05 g
  • 0.1 g (correct)
  • 0.3 g
  • 0.2 g
  • How many milliliters of a 1-in-400 stock solution are required to prepare 4L of a 1-in-2000 solution?

    <p>20 mL</p> Signup and view all the answers

    What is the conversion factor to change inches to centimeters?

    <p>1 in = 2.54 cm</p> Signup and view all the answers

    If 1.5 grams of Drug X is required for 20 mL of an 8% w/v solution, how much is needed for 5 mL?

    <p>0.3 g</p> Signup and view all the answers

    What is the total weight percentage of a solution containing 10g of a solute in 90g of solvent?

    <p>11.11% w/w</p> Signup and view all the answers

    How many tablets of Metformin will the patient take in a day if the prescription is for 1 g twice daily and the stock is 500 mg tablets?

    <p>4 tablets</p> Signup and view all the answers

    How much total active ingredient (in grams) is present when preparing 4L of a solution that is 15% w/v?

    <p>600 g</p> Signup and view all the answers

    If a child weighs 30 kg and requires 15 mg/kg of Paracetamol, how much total medication is required for one day (QDS)?

    <p>600 mg</p> Signup and view all the answers

    What is the equivalent amount in mL if a child needs 150 mg of Ranitidine and the concentration of the syrup is 15 mg/mL?

    <p>20 mL</p> Signup and view all the answers

    What is the weight of salicylic acid needed to dilute 680g of a 10% ointment to make it a 15% solution?

    <p>70 g</p> Signup and view all the answers

    If the final concentration of a solution is 0.5% w/v and 200 mL of solution is prepared, how many grams of the active ingredient are present?

    <p>1 g</p> Signup and view all the answers

    How many hours are in a week if 1 week is defined as 7 days and each day has 24 hours?

    <p>168 hours</p> Signup and view all the answers

    In a procedure involving the dilution of Chlorhexidine from a 10% stock solution to a 0.1% solution, what would be the dilution factor needed?

    <p>100</p> Signup and view all the answers

    For a prescribed corticosteroid dosage for a patient, which of the following represents an example of weight-based dosing?

    <p>15 mg/kg of body weight</p> Signup and view all the answers

    What is the correct calculation for converting feet to centimeters when given a measurement in feet?

    <p>$ ext{value in feet} imes 30.48$</p> Signup and view all the answers

    What is the total number of fluid ounces (fl oz) a patient would consume per week if a medication requires 5 mL QDS and is liquid?

    <p>28 fl oz</p> Signup and view all the answers

    Which of the following methods is mentioned for ensuring accurate conversion between different units?

    <p>Dimensional analysis</p> Signup and view all the answers

    What is the total number of mL required in a day for a 10-year-old child requiring Paracetamol at 15 mg/kg QDS, given their weight of 30 kg and a suspension concentration of 200 mg/mL?

    <p>90 mL</p> Signup and view all the answers

    What is the total daily dose of paracetamol for a 30 kg child at the recommended dose of 15 mg/kg?

    <p>600 mg</p> Signup and view all the answers

    If a patient needs to take 3 x 5 mL spoonfuls of lactulose three times a day, how much lactulose will the patient consume in one day?

    <p>60 mL</p> Signup and view all the answers

    What volume of codeine solution (5 mg/mL) is needed for a 15 kg child at a dose of 200 mcg/kg?

    <p>6 mL</p> Signup and view all the answers

    How many total liquid mL will be supplied if Prednisolone is taken as 30 mg for 6 days, then reduced by 5 mg at a time?

    <p>120 mL</p> Signup and view all the answers

    How many total doses of a 200 mg/5 mL suspension should a 30 kg child take in one day?

    <p>4</p> Signup and view all the answers

    What is the total amount of lactulose consumed if the bottle contains 400 mL and is taken at the prescribed regimen?

    <p>8 days</p> Signup and view all the answers

    How much total weight of Prednisolone is prescribed over the course of the reduction schedule?

    <p>200 mg</p> Signup and view all the answers

    If Prednisolone 30 mg is prescribed x 6/7, how many total tablets are necessary if reduced by 5 mg in 6 days?

    <p>12</p> Signup and view all the answers

    What is the dosage of codeine required for a 15 kg child if the dosage is 200 mcg/kg?

    <p>3 mL</p> Signup and view all the answers

    How many mL of D5W should be administered to provide 150 mg of dextrose?

    <p>3 mL</p> Signup and view all the answers

    What is the required volume of 80% (v/v) stock solution to prepare 250 mL of a 15% (v/v) solution?

    <p>46.875 mL</p> Signup and view all the answers

    In the formulation of BMX, how much Maalox liquid is required to make 500 mL?

    <p>229 mL</p> Signup and view all the answers

    If you have 50g of 2% sulphur ointment, how many grams of yellow soft paraffin should be added to create a 0.5% w/w ointment?

    <p>300g</p> Signup and view all the answers

    What is the main principle behind calculating dilutions?

    <p>The concentration of the active ingredient must stay constant.</p> Signup and view all the answers

    What does the term 'v/v' signify in solution concentration?

    <p>Volume to volume ratio</p> Signup and view all the answers

    When compounding solutions, what does the abbreviation 'API' stand for?

    <p>Active Pharmaceutical Ingredient</p> Signup and view all the answers

    In the example of D5W, how much dextrose is contained in a 100 mL solution?

    <p>5 g</p> Signup and view all the answers

    What method is primarily used to adjust concentrations in liquid preparations?

    <p>Dilution</p> Signup and view all the answers

    In calculating the amount of stock solution needed, why is it important to keep concentration constant?

    <p>To maintain therapeutic effectiveness</p> Signup and view all the answers

    Study Notes

    Medicine Dispensing

    • Dosage instructions should be interpreted correctly and clearly.
    • Calculations should not be done by the patient.
    • Simple measurements of dosage should be used.
    • Consider dosage forms and adjustments for children.

    Dispensing Calculations

    • Solid dosage forms:
      • Calculate the number of tablets to take each day based on the dose and frequency.
    • Liquid dosage forms:
      • Calculate the volume of liquid to take each day based on the dose and frequency.
    • Weight-based dosing:
      • Calculate the volume of liquid to be administered based on the child's weight, the dose, frequency, and duration of treatment.
    • Corticosteroid dispensing:
      • Calculate the number of tablets to be supplied based on the initial dose, reduction schedule, and duration of treatment (using various calculation methods).

    Dimensional Analysis

    • A system for converting units of measurement.
    • Multiply the original quantity by a series of conversion factors to get the desired units.

    Compounding

    • The practice of preparing medications from raw materials.
    • It is becoming less common as prefabricated dosage forms are readily available.

    Calculations with Ratios and Proportions

    • Example: Calculate the volume of D5W solution needed to deliver a specific dosage of dextrose.
    • Key principle: The concentration of the active pharmaceutical ingredient (API) remains constant.

    Dilution of Stock Solution

    • Example: Calculate the volume of stock solution needed to prepare a specific volume and concentration solution.
    • Key principle: The amount of API remains constant.

    Following a Formula

    • Example: Calculate the amount of an ingredient needed to prepare a specific volume of a compounded solution (using a given formula).
    • Key principle: The concentration of the API remains constant.

    Dilution of Solids

    • Example: Calculate the amount of excipient needed to dilute a solid ointment preparation.
    • Key principle: The weight of the API remains constant.

    Increasing Concentration

    • Example: Calculate the amount of active ingredient needed to increase the concentration of an ointment.
    • Key principle: The weight of the excipient remains constant.

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    Description

    This quiz covers essential principles of medicine dispensing, including dosage instructions, calculations for solid and liquid forms, and adjustments for children. It also explores dimensional analysis for unit conversions in medication. Test your knowledge on safe and effective dispensing practices.

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