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Malignant Hyperthermia and Muscle Contraction

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Malignant Hyperthermia and Muscle Contraction

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Questions and Answers

What is the primary ion responsible for the contraction of skeletal muscles?

Calcium (Ca++) (correct)

Potassium (K+)

Magnesium (Mg++)

Sodium (Na+)

What is the life-threatening reaction associated with General Anesthesia (GA) and Succinylcholine?

Anaphylactic Shock

Malignant Hyperthermia (correct)

Delayed Allergic Reaction

Hypotension

Where is calcium (Ca++) stored in muscle cells?

In the mitochondria

In the sarcoplasmic reticulum (correct)

In the cell membrane

In the cytoplasm

What role does Adenosine Triphosphate (ATP) play in muscle contraction?

It provides energy for ion movement Signup and view all the answers

What condition occurs due to excessive muscle contraction and heat production?

Malignant Hyperthermia Signup and view all the answers

What initiator ion is critical for starting the process of skeletal muscle contraction?

Sodium (Na+) Signup and view all the answers

What happens to CO2 levels during Malignant Hyperthermia?

They increase excessively Signup and view all the answers

What best describes the sarcoplasmic reticulum in muscle cells?

It's a network of tubules that stores calcium. Signup and view all the answers

Study Notes

Malignant Hyperthermia

Malignant hyperthermia is an excessive muscle contraction, causing extreme heat, high CO2 levels, and rapid heart rate.
This is a life-threatening reaction to general anesthesia (gases and succinylcholine).

Normal Skeletal Muscle Contraction

Calcium (Ca++) is crucial to muscle contraction, but stored in the sarcoplasmic reticulum (SR).
The SR is a network of tubes within muscle cells.
Sodium (Na+) triggers the release of Ca++.
ATP provides energy for the process.

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Description

This quiz covers the concepts of malignant hyperthermia and normal skeletal muscle contraction. Explore the physiological mechanisms behind muscle contraction and the critical components involved. Test your knowledge on how these processes can be impacted by anesthesia.