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Malignant Hyperthermia and Muscle Contraction

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Malignant Hyperthermia and Muscle Contraction

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Questions and Answers

What is the primary effect of Malignant Hyperthermia on skeletal muscles?

Skeletal muscle atrophy

Excessive muscle contraction (correct)

No muscle contraction

Decreased muscle contraction

Which ion is considered the 'initiator ion' in muscle contraction?

Sodium (Na+) (correct)

Chloride (Cl-)

Potassium (K+)

Magnesium (Mg++)

What role does Calcium (Ca++) play in muscle contraction?

It regulates protein synthesis

It acts as the main contraction ion (correct)

It inhibits muscle contraction

It initiates energy production

Where is Calcium (Ca++) stored in muscle cells?

Sarcoplasmic reticulum (D) Signup and view all the answers

What is the function of Adenosine Triphosphate (ATP) related to ions in muscles?

It uses energy to manage ion levels (D) Signup and view all the answers

Which of the following triggers Malignant Hyperthermia?

General anesthetics and succinylcholine (C) Signup and view all the answers

What condition occurs due to excessive CO2 production in Malignant Hyperthermia?

Respiratory acidosis (A) Signup and view all the answers

What describes the structure of the sarcoplasmic reticulum in muscle cells?

Web-like tubular constructs (D) Signup and view all the answers

Study Notes

Malignant Hyperthermia

Malignant hyperthermia is a life-threatening hyperthermic reaction to general anesthetics (gases and succinylcholine).
Skeletal muscles contract excessively, producing excessive heat, CO2, and tachycardia.

Normal Skeletal Muscle Contraction

Calcium (Ca++) is essential for muscle contraction.
Ca++ is stored in the sarcoplasmic reticulum (SR), which is like sacs inside the muscle cell.
Sodium (Na+) initiates the process by triggering the release of Calcium.
Adenosine Triphosphate (ATP) provides the energy for these ion movements.

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Description

Explore the critical aspects of malignant hyperthermia and its relationship to skeletal muscle contraction. This quiz covers the biochemical mechanisms behind muscle contractions, including the roles of calcium and sodium, as well as the effects of anesthetics. Test your knowledge on this life-threatening condition and the physiology of muscle function.