Malignant Hyperthermia and Muscle Contraction
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Questions and Answers

What is the primary characteristic of Malignant Hyperthermia?

  • Excessive skeletal muscle contraction leading to hyperthermia. (correct)
  • Decreased muscle contraction causing hypothermia.
  • Reduced carbon dioxide production and bradycardia.
  • Normal muscle contraction with a slight increase in body temperature.
  • What are the two primary triggers for Malignant Hyperthermia?

  • Opioids and muscle relaxants
  • Local anesthetics and sedatives
  • General anesthetic gases and succinylcholine (correct)
  • Antibiotics and anti-inflammatory drugs.
  • Which ion is primarily responsible for initiating skeletal muscle contraction?

  • Chloride (Cl-)
  • Sodium (Na+) (correct)
  • Calcium (Ca++)
  • Potassium (K+)
  • Which ion plays a major role in muscle squeeze or actual contraction?

    <p>Calcium (Ca++) (C)</p> Signup and view all the answers

    What substance is described as consuming ions for energy?

    <p>Adenosine Triphosphate (ATP) (C)</p> Signup and view all the answers

    Where is calcium typically stored in muscle cells?

    <p>In the sarcoplasmic reticulum (SR) (B)</p> Signup and view all the answers

    What is the best description of the structure of the sarcoplasmic reticulum (SR)?

    <p>Thread-like tubular networks that surround muscle cells (C)</p> Signup and view all the answers

    In the analogy provided, what does eating a biscuit and having to run 2 miles represent?

    <p>The action of ATP using ions for energy. (A)</p> Signup and view all the answers

    Study Notes

    Malignant Hyperthermia

    • Malignant hyperthermia is a life-threatening reaction to certain anesthetic agents (gases and succinylcholine).
    • Excessive muscle contractions, heat production, and elevated CO2 and heart rate occur.

    Skeletal Muscle Contraction

    • Calcium (Ca++) is crucial for muscle contraction.
    • It is stored in the sarcoplasmic reticulum (SR).
    • Sodium (Na+) initiates the process, leading to the release of Ca++.
    • Adenosine Triphosphate (ATP) provides energy for the process.

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    Description

    This quiz explores the critical aspects of malignant hyperthermia and skeletal muscle contraction. It delves into the mechanisms behind muscle contractions, including the role of calcium and sodium. Additionally, it highlights the implications of malignant hyperthermia in response to anesthetic agents.

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