Podcast
Questions and Answers
What is the primary characteristic of Malignant Hyperthermia?
What is the primary characteristic of Malignant Hyperthermia?
- Excessive skeletal muscle contraction leading to hyperthermia. (correct)
- Decreased muscle contraction causing hypothermia.
- Reduced carbon dioxide production and bradycardia.
- Normal muscle contraction with a slight increase in body temperature.
What are the two primary triggers for Malignant Hyperthermia?
What are the two primary triggers for Malignant Hyperthermia?
- Opioids and muscle relaxants
- Local anesthetics and sedatives
- General anesthetic gases and succinylcholine (correct)
- Antibiotics and anti-inflammatory drugs.
Which ion is primarily responsible for initiating skeletal muscle contraction?
Which ion is primarily responsible for initiating skeletal muscle contraction?
- Chloride (Cl-)
- Sodium (Na+) (correct)
- Calcium (Ca++)
- Potassium (K+)
Which ion plays a major role in muscle squeeze or actual contraction?
Which ion plays a major role in muscle squeeze or actual contraction?
What substance is described as consuming ions for energy?
What substance is described as consuming ions for energy?
Where is calcium typically stored in muscle cells?
Where is calcium typically stored in muscle cells?
What is the best description of the structure of the sarcoplasmic reticulum (SR)?
What is the best description of the structure of the sarcoplasmic reticulum (SR)?
In the analogy provided, what does eating a biscuit and having to run 2 miles represent?
In the analogy provided, what does eating a biscuit and having to run 2 miles represent?
Flashcards
Malignant Hyperthermia
Malignant Hyperthermia
A life-threatening condition where skeletal muscles contract uncontrollably, generating excessive heat, CO2, and rapid heartbeat.
Sodium (Na+)
Sodium (Na+)
The neurotransmitter involved in muscle contraction; triggers a chain reaction by initiating the release of calcium.
Calcium (Ca++)
Calcium (Ca++)
The primary ion responsible for muscle contraction; binds to proteins to help muscles contract.
Adenosine Triphosphate (ATP)
Adenosine Triphosphate (ATP)
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Sarcoplasmic Reticulum (SR)
Sarcoplasmic Reticulum (SR)
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Cytoplasm
Cytoplasm
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Normal Skeletal Muscle Contraction
Normal Skeletal Muscle Contraction
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Gases and Succinylcholine
Gases and Succinylcholine
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Study Notes
Malignant Hyperthermia
- Malignant hyperthermia is a life-threatening reaction to certain anesthetic agents (gases and succinylcholine).
- Excessive muscle contractions, heat production, and elevated CO2 and heart rate occur.
Skeletal Muscle Contraction
- Calcium (Ca++) is crucial for muscle contraction.
- It is stored in the sarcoplasmic reticulum (SR).
- Sodium (Na+) initiates the process, leading to the release of Ca++.
- Adenosine Triphosphate (ATP) provides energy for the process.
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