10 Questions
What is the role of integrin molecules when phagocytes are 'rolling' across the endothelium?
Facilitates firm adhesion when chemokine binds to the receptor
What molecule is directly associated with the inhibition of virus gene expression and assembly?
Interferon
What are the two main functions of dendritic cells?
Responding to microbes by secreting cytokines to initiate inflammation and stimulating adaptive immune system, serving as the bridge between innate and adaptive immunity
What kind of receptor recognizes microbial patterns such as a bacterial cell wall lipid?
Toll-Like Receptor (TLR)
What is the primary role of a Natural Killer (NK) cell?
Killing cells infected with viruses
How do naïve B and T cells migrate out of the lymph nodes to the site of an infection?
Through Efferent Lymphatic Vessel
What differentiates a naïve B cell from a plasma cell?
Plasma cells do not recirculate between blood and lymphoid organs like naïve B cells.
How do effector T lymphocytes migrate from lymphoid tissues to sites of infection?
Through high endothelial venules (HEVs)
What is the role of the complement system in the immune response?
Enhancing phagocytosis by macrophages
Where do plasma cells primarily secrete antibodies?
In the bone marrow
Test your knowledge on how lymphocytes migrate from lymph nodes to the site of infection and participate in the immune response. Learn about the processes involved in the movement of naïve and effector lymphocytes.
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