How Well Do You Know Lymphocyte Migration Patterns?
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Questions and Answers

What is the main function of effector T cells?

  • To secrete antibodies
  • To migrate to lymph nodes and find antigens
  • To differentiate into plasma cells
  • To migrate to sites of infection and eliminate microbes (correct)

What is the function of plasma cells?

  • To migrate to sites of infection and eliminate microbes
  • To locate antigens
  • To differentiate into effector T cells
  • To secrete antibodies (correct)

What is the function of chemokines in the migration of naive T cells to lymph nodes?

  • To scan the surfaces of dendritic cells for antigens
  • To display antigens on HEV surfaces
  • To bind to the chemokine receptor CCR7 expressed on naive T cells (correct)
  • To migrate into the T cell zone

Which chemokine receptor is expressed on naive B cells?

<p>CXCR5 (B)</p> Signup and view all the answers

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

<p>The T cell forms stable conjugates with the dendritic cell and is activated (D)</p> Signup and view all the answers

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

<p>To increase the likelihood of the correct T cell finding its antigen (C)</p> Signup and view all the answers

Where do most antibody-secreting plasma cells migrate to?

<p>The bone marrow (C)</p> Signup and view all the answers

What are memory T cells?

<p>T cells that can mount secondary responses to captured antigens (A)</p> Signup and view all the answers

Where do effector cells migrate to after they are generated upon T cell activation?

<p>The infected tissues (D)</p> Signup and view all the answers

What is the function of naive lymphocytes?

<p>To constantly recirculate between the blood and peripheral lymphoid organs (B)</p> Signup and view all the answers

What are high endothelial venules (HEVs)?

<p>Specialized postcapillary venules through which naive T cells enter lymph nodes (D)</p> Signup and view all the answers

What controls the precise patterns of migration of naive and activated T cells?

<p>Specific signals (B)</p> Signup and view all the answers

What is the main function of effector T cells?

<p>To migrate to sites of infection and eliminate microbes (D)</p> Signup and view all the answers

What is the function of plasma cells?

<p>To secrete antibodies (B)</p> Signup and view all the answers

What is the function of chemokines in the migration of naive T cells to lymph nodes?

<p>To bind to the chemokine receptor CCR7 expressed on naive T cells (C)</p> Signup and view all the answers

Which chemokine receptor is expressed on naive B cells?

<p>CXCR5 (D)</p> Signup and view all the answers

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

<p>The T cell forms stable conjugates with the dendritic cell and is activated (C)</p> Signup and view all the answers

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

<p>To increase the likelihood of the correct T cell finding its antigen (B)</p> Signup and view all the answers

Where do most antibody-secreting plasma cells migrate to?

<p>The bone marrow (D)</p> Signup and view all the answers

What are memory T cells?

<p>T cells that can mount secondary responses to captured antigens (A)</p> Signup and view all the answers

Where do effector cells migrate to after they are generated upon T cell activation?

<p>The infected tissues (B)</p> Signup and view all the answers

What is the function of naive lymphocytes?

<p>To constantly recirculate between the blood and peripheral lymphoid organs (A)</p> Signup and view all the answers

What are high endothelial venules (HEVs)?

<p>Specialized postcapillary venules through which naive T cells enter lymph nodes (A)</p> Signup and view all the answers

What controls the precise patterns of migration of naive and activated T cells?

<p>Specific signals (B)</p> Signup and view all the answers

Which type of lymphocyte does not need to migrate to sites of infection?

<p>Plasma cells (A)</p> Signup and view all the answers

What is the role of effector T cells in combating infections?

<p>They bind to and eliminate microbes at sites of infection (B)</p> Signup and view all the answers

What is the function of plasma cells in mucosal organs?

<p>They secrete antibodies that enter the lumens of these organs (D)</p> Signup and view all the answers

How do naive T cells enter lymph nodes?

<p>Through specialized postcapillary venules (D)</p> Signup and view all the answers

What is the function of chemokines produced in the T cell zones of the lymph nodes?

<p>To bind to the chemokine receptor CCR7 (A)</p> Signup and view all the answers

What is the role of dendritic cells in activating T cells?

<p>To display antigens (D)</p> Signup and view all the answers

What is the function of effector cells?

<p>To locate and eliminate microbes (D)</p> Signup and view all the answers

What is the role of chemokines that bind CXCR5?

<p>To migrate B cells to follicles (A)</p> Signup and view all the answers

What is the function of memory T cells?

<p>To mount secondary responses to captured antigens (C)</p> Signup and view all the answers

What is the likelihood of the correct T cell finding its antigen in peripheral lymphoid organs?

<p>High (C)</p> Signup and view all the answers

Where do most plasma cells migrate to?

<p>Bone marrow (D)</p> Signup and view all the answers

What is the role of memory cells that permanently reside in epithelial tissues?

<p>To respond rapidly to eliminate the infection (C)</p> Signup and view all the answers

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