How Well Do You Know Lymphocyte Migration Patterns?

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What is the main function of effector T cells?

To secrete antibodies

To migrate to lymph nodes and find antigens

To differentiate into plasma cells

To migrate to sites of infection and eliminate microbes (correct)

What is the function of plasma cells?

To migrate to sites of infection and eliminate microbes

To locate antigens

To differentiate into effector T cells

To secrete antibodies (correct)

What is the function of chemokines in the migration of naive T cells to lymph nodes?

To scan the surfaces of dendritic cells for antigens

To display antigens on HEV surfaces

To bind to the chemokine receptor CCR7 expressed on naive T cells (correct)

To migrate into the T cell zone

Which chemokine receptor is expressed on naive B cells?

CXCR5 Signup and view all the answers

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

The T cell forms stable conjugates with the dendritic cell and is activated Signup and view all the answers

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

To increase the likelihood of the correct T cell finding its antigen Signup and view all the answers

Where do most antibody-secreting plasma cells migrate to?

The bone marrow Signup and view all the answers

What are memory T cells?

T cells that can mount secondary responses to captured antigens Signup and view all the answers

Where do effector cells migrate to after they are generated upon T cell activation?

The infected tissues Signup and view all the answers

What is the function of naive lymphocytes?

To constantly recirculate between the blood and peripheral lymphoid organs Signup and view all the answers

What are high endothelial venules (HEVs)?

Specialized postcapillary venules through which naive T cells enter lymph nodes Signup and view all the answers

What controls the precise patterns of migration of naive and activated T cells?

Specific signals Signup and view all the answers

What is the main function of effector T cells?

To migrate to sites of infection and eliminate microbes Signup and view all the answers

What is the function of plasma cells?

To secrete antibodies Signup and view all the answers

What is the function of chemokines in the migration of naive T cells to lymph nodes?

To bind to the chemokine receptor CCR7 expressed on naive T cells Signup and view all the answers

Which chemokine receptor is expressed on naive B cells?

CXCR5 Signup and view all the answers

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

The T cell forms stable conjugates with the dendritic cell and is activated Signup and view all the answers

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

To increase the likelihood of the correct T cell finding its antigen Signup and view all the answers

Where do most antibody-secreting plasma cells migrate to?

The bone marrow Signup and view all the answers

What are memory T cells?

T cells that can mount secondary responses to captured antigens Signup and view all the answers

Where do effector cells migrate to after they are generated upon T cell activation?

The infected tissues Signup and view all the answers

What is the function of naive lymphocytes?

To constantly recirculate between the blood and peripheral lymphoid organs Signup and view all the answers

What are high endothelial venules (HEVs)?

Specialized postcapillary venules through which naive T cells enter lymph nodes Signup and view all the answers

What controls the precise patterns of migration of naive and activated T cells?

Specific signals Signup and view all the answers

Which type of lymphocyte does not need to migrate to sites of infection?

Plasma cells Signup and view all the answers

What is the role of effector T cells in combating infections?

They bind to and eliminate microbes at sites of infection Signup and view all the answers

What is the function of plasma cells in mucosal organs?

They secrete antibodies that enter the lumens of these organs Signup and view all the answers

How do naive T cells enter lymph nodes?

Through specialized postcapillary venules Signup and view all the answers

What is the function of chemokines produced in the T cell zones of the lymph nodes?

To bind to the chemokine receptor CCR7 Signup and view all the answers

What is the role of dendritic cells in activating T cells?

To display antigens Signup and view all the answers

What is the function of effector cells?

To locate and eliminate microbes Signup and view all the answers

What is the role of chemokines that bind CXCR5?

To migrate B cells to follicles Signup and view all the answers

What is the function of memory T cells?

To mount secondary responses to captured antigens Signup and view all the answers

What is the likelihood of the correct T cell finding its antigen in peripheral lymphoid organs?

High Signup and view all the answers

Where do most plasma cells migrate to?

Bone marrow Signup and view all the answers

What is the role of memory cells that permanently reside in epithelial tissues?

To respond rapidly to eliminate the infection Signup and view all the answers

How Well Do You Know Lymphocyte Migration Patterns?

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Questions and Answers

What is the main function of effector T cells?

What is the function of plasma cells?

What is the function of chemokines in the migration of naive T cells to lymph nodes?

Which chemokine receptor is expressed on naive B cells?

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

Where do most antibody-secreting plasma cells migrate to?

What are memory T cells?

Where do effector cells migrate to after they are generated upon T cell activation?

What is the function of naive lymphocytes?

What are high endothelial venules (HEVs)?

What controls the precise patterns of migration of naive and activated T cells?

What is the main function of effector T cells?

What is the function of plasma cells?

What is the function of chemokines in the migration of naive T cells to lymph nodes?

Which chemokine receptor is expressed on naive B cells?

What happens when a T cell specifically recognizes an antigen on a dendritic cell?

Why are microbial antigens concentrated in the same regions of peripheral lymphoid organs through which naive T cells circulate?

Where do most antibody-secreting plasma cells migrate to?

What are memory T cells?

Where do effector cells migrate to after they are generated upon T cell activation?

What is the function of naive lymphocytes?

What are high endothelial venules (HEVs)?

What controls the precise patterns of migration of naive and activated T cells?

Which type of lymphocyte does not need to migrate to sites of infection?

What is the role of effector T cells in combating infections?

What is the function of plasma cells in mucosal organs?

How do naive T cells enter lymph nodes?

What is the function of chemokines produced in the T cell zones of the lymph nodes?

What is the role of dendritic cells in activating T cells?

What is the function of effector cells?

What is the role of chemokines that bind CXCR5?

What is the function of memory T cells?

What is the likelihood of the correct T cell finding its antigen in peripheral lymphoid organs?

Where do most plasma cells migrate to?

What is the role of memory cells that permanently reside in epithelial tissues?

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