Laboratory Diagnosis of HSV Infections

To detect the presence of multinucleated giant cells, suggesting HSV infection.

Through immunofluorescence, DNA probes, or PCR.

Immunofluorescence or ELISA.

<p>It presents with fever, sore throat, enlarged lymph nodes and spleen, rash, and commonly hepatitis.</p> Signup and view all the answers

<p>In adolescence, 50% of cases manifest as infectious mononucleosis (IMN), while childhood infections are usually asymptomatic.</p> Signup and view all the answers

<p>Paul Bunnel test.</p> Signup and view all the answers

<p>Asymptomatic latent infection or infectious mononucleosis-like syndrome</p> Signup and view all the answers

<p>Abortion, still-birth, cytomegalic inclusion disease with congenital anomalies like blindness, deafness, mental retardation</p> Signup and view all the answers

<p>Detection of intranuclear cytomegalic inclusions, CMV nucleic acids in tissues, isolation of virus from throat washings and urine, detection of IgM or rising titer of IgG</p> Signup and view all the answers

<p>Pneumonia, retinitis, graft rejection, disseminated disease</p> Signup and view all the answers

<p>Restenosis</p> Signup and view all the answers

<p>Heterophile antibodies</p> Signup and view all the answers

<p>Epstein-Barr virus, cytomegalovirus, HIV, Herpes simplex virus, Measles, Mumps, Rubella, Coxsackie, Adenovirus</p> Signup and view all the answers

<p>Rubella is an acute infectious disease characterized by fever, rash, and enlargement of occipital and cervical lymph nodes. It is caused by a single stranded RNA virus belonging to the Togavirus family.</p> Signup and view all the answers

<p>Rubella virus is not transmitted by arthropods. It is transmitted by infection of neonates, children, and adults through respiratory droplets.</p> Signup and view all the answers

<p>Initial replication of the virus occurs in the nasopharynx and local lymph nodes, then spreads via the blood to internal organs and skin. This leads to the appearance of a maculopapular rash, fever, and enlargement of cervical or occipital lymph nodes.</p> Signup and view all the answers

<p>Congenital Rubella Syndrome occurs when Rubella infection of pregnant women leads to transplacental transmission to the fetus. This can result in congenital anomalies like heart defects, cataract, deafness, blindness, and mental retardation.</p> Signup and view all the answers

<p>Congenital heart defects, cataract, deafness, blindness, meningoencephalitis, mental retardation, hepatosplenomegaly</p> Signup and view all the answers