Laboratory Diagnosis of HSV Infections

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Questions and Answers

Which virus belongs to the Togavirus family and is not transmitted by arthropods?

  • Herpes simplex virus
  • Epstein-Barr virus
  • Cytomegalovirus
  • Rubella virus (correct)

What is the initial site of replication of Rubella virus in postnatal rubella infection?

  • Spleen
  • Liver
  • Skin
  • Nasopharynx & local lymph nodes (correct)

Congenital rubella syndrome results from Rubella infection of pregnant women during which trimester of pregnancy?

  • First trimester (correct)
  • Second trimester
  • Any trimester
  • Third trimester

Which symptom is characteristic of postnatal rubella infection?

<p>Maculopapular rash, fever, and cervical lymph node enlargement (D)</p> Signup and view all the answers

What type of immunity follows a single attack of postnatal rubella infection?

<p>Solid immunity (C)</p> Signup and view all the answers

In congenital rubella syndrome, which organ defect is NOT associated with the infection?

<p>Kidney failure (A)</p> Signup and view all the answers

What is a diagnostic method used in the laboratory for HSV infections that involves staining scrapings with Giemsa?

<p>Tzanck smear (C)</p> Signup and view all the answers

What is the diagnostic method used to detect Epstein Barr virus (EBV) in lymphoid tissue or saliva?

<p>Detection of viral DNA by PCR (D)</p> Signup and view all the answers

Which clinical feature is associated with mononucleosis caused by EBV?

<p>Enlarged lymph nodes and spleen (D)</p> Signup and view all the answers

Which test can be used to detect heterophils antibodies that agglutinate sheep RBCs in infectious mononucleosis diagnosis?

<p>Paul Bunnel test (D)</p> Signup and view all the answers

What type of immunity does primary infection with Epstein Barr virus (EBV) result in?

<p>Life-long immunity (B)</p> Signup and view all the answers

What is the primary method for detecting HSV infections in vesicular fluid?

<p>Detection of viral antigens by immunofluorescence (C)</p> Signup and view all the answers

What is a common laboratory diagnostic method for CMV infections?

<p>Detection of intranuclear cytomegalic inclusions (B)</p> Signup and view all the answers

What is a characteristic symptom of congenital CMV infection?

<p>Hepatosplenomegaly (C)</p> Signup and view all the answers

What is a possible complication of CMV infection in immunocompromised individuals?

<p>Pneumonia (C)</p> Signup and view all the answers

What is a common feature of EBV infection?

<p>Infectious mononucleosis-like syndrome (D)</p> Signup and view all the answers

What is a possible source of perinatal CMV infection?

<p>Breast milk (B)</p> Signup and view all the answers

What is a distinguishing feature of CMV infection from EBV infection?

<p>Intranuclear cytomegalic inclusions (C)</p> Signup and view all the answers

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