Laboratory Diagnosis of HSV Infections
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Questions and Answers

Which virus belongs to the Togavirus family and is not transmitted by arthropods?

  • Herpes simplex virus
  • Epstein-Barr virus
  • Cytomegalovirus
  • Rubella virus (correct)
  • What is the initial site of replication of Rubella virus in postnatal rubella infection?

  • Spleen
  • Liver
  • Skin
  • Nasopharynx & local lymph nodes (correct)
  • Congenital rubella syndrome results from Rubella infection of pregnant women during which trimester of pregnancy?

  • First trimester (correct)
  • Second trimester
  • Any trimester
  • Third trimester
  • Which symptom is characteristic of postnatal rubella infection?

    <p>Maculopapular rash, fever, and cervical lymph node enlargement</p> Signup and view all the answers

    What type of immunity follows a single attack of postnatal rubella infection?

    <p>Solid immunity</p> Signup and view all the answers

    In congenital rubella syndrome, which organ defect is NOT associated with the infection?

    <p>Kidney failure</p> Signup and view all the answers

    What is a diagnostic method used in the laboratory for HSV infections that involves staining scrapings with Giemsa?

    <p>Tzanck smear</p> Signup and view all the answers

    What is the diagnostic method used to detect Epstein Barr virus (EBV) in lymphoid tissue or saliva?

    <p>Detection of viral DNA by PCR</p> Signup and view all the answers

    Which clinical feature is associated with mononucleosis caused by EBV?

    <p>Enlarged lymph nodes and spleen</p> Signup and view all the answers

    Which test can be used to detect heterophils antibodies that agglutinate sheep RBCs in infectious mononucleosis diagnosis?

    <p>Paul Bunnel test</p> Signup and view all the answers

    What type of immunity does primary infection with Epstein Barr virus (EBV) result in?

    <p>Life-long immunity</p> Signup and view all the answers

    What is the primary method for detecting HSV infections in vesicular fluid?

    <p>Detection of viral antigens by immunofluorescence</p> Signup and view all the answers

    What is a common laboratory diagnostic method for CMV infections?

    <p>Detection of intranuclear cytomegalic inclusions</p> Signup and view all the answers

    What is a characteristic symptom of congenital CMV infection?

    <p>Hepatosplenomegaly</p> Signup and view all the answers

    What is a possible complication of CMV infection in immunocompromised individuals?

    <p>Pneumonia</p> Signup and view all the answers

    What is a common feature of EBV infection?

    <p>Infectious mononucleosis-like syndrome</p> Signup and view all the answers

    What is a possible source of perinatal CMV infection?

    <p>Breast milk</p> Signup and view all the answers

    What is a distinguishing feature of CMV infection from EBV infection?

    <p>Intranuclear cytomegalic inclusions</p> Signup and view all the answers

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