18 Questions
Which virus belongs to the Togavirus family and is not transmitted by arthropods?
Rubella virus
What is the initial site of replication of Rubella virus in postnatal rubella infection?
Nasopharynx & local lymph nodes
Congenital rubella syndrome results from Rubella infection of pregnant women during which trimester of pregnancy?
First trimester
Which symptom is characteristic of postnatal rubella infection?
Maculopapular rash, fever, and cervical lymph node enlargement
What type of immunity follows a single attack of postnatal rubella infection?
Solid immunity
In congenital rubella syndrome, which organ defect is NOT associated with the infection?
Kidney failure
What is a diagnostic method used in the laboratory for HSV infections that involves staining scrapings with Giemsa?
Tzanck smear
What is the diagnostic method used to detect Epstein Barr virus (EBV) in lymphoid tissue or saliva?
Detection of viral DNA by PCR
Which clinical feature is associated with mononucleosis caused by EBV?
Enlarged lymph nodes and spleen
Which test can be used to detect heterophils antibodies that agglutinate sheep RBCs in infectious mononucleosis diagnosis?
Paul Bunnel test
What type of immunity does primary infection with Epstein Barr virus (EBV) result in?
Life-long immunity
What is the primary method for detecting HSV infections in vesicular fluid?
Detection of viral antigens by immunofluorescence
What is a common laboratory diagnostic method for CMV infections?
Detection of intranuclear cytomegalic inclusions
What is a characteristic symptom of congenital CMV infection?
Hepatosplenomegaly
What is a possible complication of CMV infection in immunocompromised individuals?
Pneumonia
What is a common feature of EBV infection?
Infectious mononucleosis-like syndrome
What is a possible source of perinatal CMV infection?
Breast milk
What is a distinguishing feature of CMV infection from EBV infection?
Intranuclear cytomegalic inclusions
Learn about the laboratory methods used for diagnosing Herpes Simplex Virus (HSV) infections. This quiz covers techniques like Tzanck smear, viral antigen detection, DNA probes, PCR, and virus isolation from herpetic lesions.
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