Laboratory Diagnosis of HSV Infections
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Questions and Answers

In a Tzanck smear, the presence of multinucleated giant cells indicates infection with Epstein Barr virus (EBV).

False

Epstein Barr virus (EBV) is transmitted by infected blood transfusion.

False

Primary infection with Epstein Barr virus in childhood typically results in lifelong immunity.

True

Detection of viral antigens in vesicular fluid using PCR is a common method for diagnosing Herpes Simplex Virus (HSV) infections.

<p>True</p> Signup and view all the answers

Infectious mononucleosis caused by Epstein Barr virus can manifest as fever, sore throat, enlarged lymph nodes, rash, and hepatitis.

<p>True</p> Signup and view all the answers

The Paul Bunnel test is used to detect the presence of EB virus in the blood.

<p>False</p> Signup and view all the answers

Rubella is caused by a DNA virus.

<p>False</p> Signup and view all the answers

Rubella can be transmitted by arthropods.

<p>False</p> Signup and view all the answers

Congenital rubella syndrome can lead to cataract in the affected fetus.

<p>True</p> Signup and view all the answers

Epstein-Barr virus (EBV) can cause infectious mononucleosis.

<p>True</p> Signup and view all the answers

Maculopapular rash in rubella is due to direct viral effects on the skin.

<p>False</p> Signup and view all the answers

Infectious mononucleosis caused by Epstein-Barr virus (EBV) leads to lifelong immunity.

<p>True</p> Signup and view all the answers

CMV infection can lead to restenosis in coronary angioplasty patients.

<p>True</p> Signup and view all the answers

In immunocompromised hosts, CMV can cause pneumonia, retinitis, graft rejection, and disseminated disease.

<p>True</p> Signup and view all the answers

Congenital CMV infection can lead to blindness, deafness, mental retardation, and microcephaly in newborns.

<p>True</p> Signup and view all the answers

One of the diagnostic methods for congenital CMV infection is detecting intranuclear cytomegalic inclusions.

<p>True</p> Signup and view all the answers

Polyclonal activation of B cells is commonly observed in Epstein Barr virus (EBV) infection.

<p>True</p> Signup and view all the answers

Detection of IgM or rising titer of IgG is not useful in diagnosing congenital CMV infection.

<p>False</p> Signup and view all the answers

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