Nutrition chapter 9🍏
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Nutrition chapter 9🍏

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What role does the hormone hepcidin play in the body?

  • Enhances digestion of iron from food sources
  • Facilitates breakdown of toxins in the liver
  • Stimulates production of red blood cells
  • Regulates iron absorption and storage (correct)
  • Which of the following is a symptom of iron deficiency anemia?

  • Shortness of breath during exertion (correct)
  • Increased muscle mass
  • Enhanced energy production
  • Improved cognitive function
  • What is a common food source of both iron and zinc?

  • Dark green vegetables
  • Dairy products
  • Whole grains
  • Fish and seafood (correct)
  • Which statement about iron overload is accurate?

    <p>Toxicity symptoms can include liver damage and diabetes</p> Signup and view all the answers

    What happens to iron absorption when the body has sufficient iron stores?

    <p>Absorption is diminished to prevent toxicity</p> Signup and view all the answers

    Which mineral is critical for the structure of proteins and has no known deficiency symptoms?

    <p>Sulfate</p> Signup and view all the answers

    What is a major consequence of iron deficiency?

    <p>Impaired oxygen transport in the blood</p> Signup and view all the answers

    Which of the following can lead to symptoms of iron toxicity?

    <p>Excessive supplementation of iron</p> Signup and view all the answers

    What is the primary cause of iron deficiency?

    <p>Inadequate intake from iron-poor food choices or blood loss</p> Signup and view all the answers

    Which stage of iron deficiency is characterized by low serum ferritin levels?

    <p>Stage 1</p> Signup and view all the answers

    What symptom is NOT commonly associated with iron-deficiency anemia?

    <p>Rapid weight gain</p> Signup and view all the answers

    What factor enhances the absorption of nonheme iron?

    <p>MFP factor</p> Signup and view all the answers

    Which demographic group has a daily iron requirement of 18 mg?

    <p>Women of childbearing age</p> Signup and view all the answers

    Iron overload can lead to which of the following health risks?

    <p>Increased risk of liver cancer</p> Signup and view all the answers

    Which of the following is a nonfood substance that individuals with pica may crave?

    <p>Ice</p> Signup and view all the answers

    What is a serious risk associated with rapid ingestion of iron supplements?

    <p>Iron poisoning</p> Signup and view all the answers

    What is a primary function of zinc in the body?

    <p>Activates over 2700 enzymes for various bodily functions</p> Signup and view all the answers

    Which food source is particularly rich in zinc?

    <p>Shellfish</p> Signup and view all the answers

    What condition can arise from excessive zinc intake?

    <p>Copper-deficiency anemia</p> Signup and view all the answers

    What is a consequence of zinc deficiency during pregnancy?

    <p>Growth retardation in the fetus</p> Signup and view all the answers

    Which statement about selenium is true?

    <p>It functions primarily as an antioxidant nutrient</p> Signup and view all the answers

    Which food is considered a good source of selenium?

    <p>Meats and shellfish</p> Signup and view all the answers

    Iodine deficiency is primarily associated with which condition?

    <p>Goiter and cognitive impairment</p> Signup and view all the answers

    What is a potential result of excessive iodine intake?

    <p>Thyroid enlargement</p> Signup and view all the answers

    What is a key function of copper in the human body?

    <p>Acts as a cofactor for enzymes involved in various metabolic processes</p> Signup and view all the answers

    Which food source is commonly associated with manganese intake?

    <p>Leafy green vegetables</p> Signup and view all the answers

    What can excessive fluoride intake during tooth development lead to?

    <p>Fluorosis</p> Signup and view all the answers

    Which trace mineral is essential for functioning as part of several enzymes but has no known deficiency symptoms?

    <p>Molybdenum</p> Signup and view all the answers

    What is a consequence of chromium deficiency?

    <p>Impaired glucose tolerance</p> Signup and view all the answers

    What is the primary role of sodium in the body?

    <p>To regulate fluid balance outside of cells</p> Signup and view all the answers

    Which major mineral is known for its critical role in muscle contractions and nerve transmission?

    <p>Calcium</p> Signup and view all the answers

    What percentage of the body's calcium is stored in bones and teeth?

    <p>99%</p> Signup and view all the answers

    Which two minerals are predominantly necessary for the structure of bones?

    <p>Calcium and Phosphorus</p> Signup and view all the answers

    What health concern is primarily linked to underconsumption of calcium and potassium?

    <p>Chronic diseases</p> Signup and view all the answers

    What is a common reason why sodium levels fluctuate in the body?

    <p>Dietary intake</p> Signup and view all the answers

    What is the function of potassium within the body?

    <p>Influencing fluid balance</p> Signup and view all the answers

    Which major mineral is primarily involved in energy metabolism?

    <p>Phosphorus</p> Signup and view all the answers

    Which group has the highest daily iron requirement among the following?

    <p>Pregnant women</p> Signup and view all the answers

    What is the primary cause of iron deficiency in most individuals?

    <p>Inadequate intake from iron-poor food choices</p> Signup and view all the answers

    Which laboratory measure indicates Stage 1 of iron deficiency?

    <p>Low serum ferritin levels</p> Signup and view all the answers

    What is a typical symptom of iron-deficiency anemia?

    <p>Pallor</p> Signup and view all the answers

    Which substance is known to inhibit iron absorption?

    <p>Phytates</p> Signup and view all the answers

    What is one of the common cravings exhibited by individuals with pica due to iron deficiency?

    <p>Ice</p> Signup and view all the answers

    What serious outcome can arise from iron poisoning?

    <p>Fatality, especially in young children</p> Signup and view all the answers

    Which of the following best describes iron overload?

    <p>Tissue damage and increased risk of diseases</p> Signup and view all the answers

    Which of the following is a factor that enhances the absorption of iron?

    <p>MFP factor</p> Signup and view all the answers

    What is a common effect of severe iron deficiency beyond low hemoglobin levels?

    <p>Accumulation of erythrocyte protoporphyrin</p> Signup and view all the answers

    What is the recommended daily intake of calcium for adults aged 19 to 50?

    <p>1000 mg</p> Signup and view all the answers

    Which of the following vegetables is NOT considered a good source of calcium due to low absorption rates?

    <p>Spinach</p> Signup and view all the answers

    What percentage of calcium can infants and children absorb?

    <p>60%</p> Signup and view all the answers

    Which mineral is primarily found in combination with calcium in the body's structures?

    <p>Phosphorus</p> Signup and view all the answers

    What is the best source of phosphorus?

    <p>Animal protein</p> Signup and view all the answers

    For which life stage is the calcium recommendation the highest at 1300 mg per day?

    <p>Adolescents</p> Signup and view all the answers

    Which group is recommended to consume 1200 mg of calcium daily?

    <p>Women over age 50 and adults over age 70</p> Signup and view all the answers

    Which food source is NOT typically rich in calcium?

    <p>Red pepper</p> Signup and view all the answers

    What is the absorption rate of calcium for other adults?

    <p>20-30%</p> Signup and view all the answers

    Which of the following is NOT a source of abundant calcium?

    <p>Refined sugars</p> Signup and view all the answers

    What is a critical function of magnesium in the body?

    <p>Bone mineralization</p> Signup and view all the answers

    Which source is rich in sulfate?

    <p>Whole grains</p> Signup and view all the answers

    What can cause toxicity specifically related to magnesium?

    <p>Non-food sources of magnesium</p> Signup and view all the answers

    Which of the following statements about iron absorption is accurate?

    <p>It is tightly regulated by the body.</p> Signup and view all the answers

    What role does sulfur play in the body?

    <p>Synthesizing sulfur-containing amino acids</p> Signup and view all the answers

    What symptom might occur due to severe magnesium deficiency?

    <p>Low blood calcium</p> Signup and view all the answers

    Which mineral is known for its critical role in energy production and cell growth?

    <p>Iron</p> Signup and view all the answers

    What could potentially occur from excessive intake of sulfur amino acids?

    <p>Suppressed growth</p> Signup and view all the answers

    Which of the following food groups provides the most magnesium?

    <p>Nuts</p> Signup and view all the answers

    What might indicate a deficiency in magnesium?

    <p>Bizarre movements</p> Signup and view all the answers

    Study Notes

    Iron Deficiency

    • Most common nutrient deficiency worldwide
    • Prevalent in preschool children, pregnant women, toddlers, adolescent females, and women of childbearing age
    • Caused by inadequate intake of iron-rich foods or blood loss

    Iron Deficiency Stages

    • Stage 1: Depleted iron stores, low serum ferritin levels
    • Stage 2: Decreased transport iron, low serum iron and high transferrin levels
    • Stage 3: Limited hemoglobin production, low hemoglobin and hematocrit values, accumulation of erythrocyte protoporphyrin

    Iron Deficiency Anemia

    • Occurs when severe iron depletion results in low hemoglobin concentration
    • Symptoms: fatigue, weakness, headaches, apathy, pallor, and poor cold tolerance

    Pica

    • Craving for nonfood substances like ice, chalk, starch, and clay
    • Particularly common in iron-deficient women and children in low-income households

    Iron Overload

    • Often caused by hemochromatosis, a genetic disorder
    • Can lead to tissue damage, infections, and increased risks of diabetes, liver cancer, heart disease, and arthritis

    Iron Poisoning

    • Rapid ingestion of large amounts of iron, especially from supplements, can be fatal
    • Keep iron supplements out of reach of children

    Iron Recommendations

    • Iron needs vary depending on age and gender
    • Women of childbearing age require higher iron intake (18 mg/day) than men (8 mg/day)

    Food Sources of Iron

    • Heme Iron: More absorbable, found in meat, poultry, and fish
    • Nonheme Iron: Found in plant and animal foods
    • MFP factor (meat, fish, poultry) and vitamin C enhance iron absorption
    • Tannins, calcium, and phytates inhibit iron absorption

    Magnesium

    • Involved in bone mineralization, protein production, enzyme activity, muscle contraction, and nerve impulse transmission
    • Essential for hundreds of enzymes and other cellular functions
    • Deficiency symptoms: low blood calcium, muscle cramps, confusion, seizures, bizarre movements, hallucinations, difficulty swallowing, and growth failure in children
    • Toxicity from non-food sources can cause diarrhea, nausea, abdominal cramps, acid-base imbalance, and potassium depletion
    • Sources: nuts, legumes, whole grains, dark green vegetables, seafood, chocolate, and cocoa

    Sulfate

    • Oxidized form of sulfur found in foods and water
    • Necessary for synthesizing important sulfur-containing compounds, such as sulfur-containing amino acids
    • Sulfur-containing amino acids are important for protein structure
    • Skin, hair, and nails contain rigid proteins with high sulfur content
    • Component of certain amino acids, the vitamins biotin and thiamin, and the hormone insulin
    • Stabilizes protein shape by forming sulfur-sulfur bridges
    • No recommended intake, and deficiencies are unknown
    • Protein deficiency would likely occur before a sulfate deficiency
    • Toxicity would only occur from excess sulfur amino acid consumption, which can suppress growth
    • Sources: all protein-containing foods such as meat, fish, poultry, eggs, milk, legumes, and nuts

    Major Minerals

    • Needed in larger amounts than trace minerals
    • Play various roles in the body, including fluid balance, nerve function, muscle contraction, and bone health
    • Deficiencies and excesses can cause health problems

    Iron Function

    • Component of hemoglobin in red blood cells and myoglobin in muscle cells
    • Helps these proteins carry and release oxygen
    • Vital for energy production, cell growth, and synthesis of amino acids, hormones, and neurotransmitters

    Iron Absorption and Regulation

    • The body tightly regulates iron absorption and storage
    • Special proteins transport and store iron
    • Hepcidin hormone plays a central role in maintaining iron balance

    Zinc Function

    • Essential for the activation of over 2700 enzymes involved in various bodily functions
    • Functions include growth, immune function, wound healing, taste perception, and reproduction

    Zinc Absorption and Transport

    • Zinc absorption is regulated by the body's needs
    • Albumin is the main transport protein for zinc in the blood

    Zinc Deficiency

    • Can lead to growth retardation, impaired immune function, loss of appetite, and developmental problems during pregnancy

    Zinc Toxicity

    • Excessive zinc intake can interfere with copper absorption, leading to copper-deficiency anemia
    • High doses of zinc can cause gastrointestinal distress, headaches, and other symptoms

    Zinc Recommendations and Food Sources

    • Most people in the United States meet their zinc requirements
    • Good sources include protein-rich foods like shellfish, meats, poultry, milk products, legumes, and whole grains

    Zinc Supplementation

    • Generally not recommended unless prescribed for a diagnosed deficiency

    Selenium Function

    • Functions as an antioxidant nutrient, primarily as part of glutathione peroxidase enzymes
    • Works with vitamin E to protect cells from free radical damage

    Selenium and Cancer

    • Adequate selenium intake is associated with lower cancer risks
    • Supplementation has not been shown to provide additional benefits in populations with sufficient selenium intake

    Selenium Deficiency

    • Deficiency is rare
    • Has been linked to Keshan disease, a heart condition prevalent in selenium-deficient regions of China

    Selenium Toxicity

    • Excessive selenium intake can cause gastrointestinal problems, hair and nail loss, and nervous system damage

    Selenium Recommendations and Food Sources

    • A varied diet of unprocessed foods generally provides adequate selenium
    • Good sources include meats, shellfish, vegetables, and grains grown in selenium-rich soil

    Iodine Function

    • Crucial component of thyroid hormones, which regulate metabolism, growth, development, and various bodily functions

    Iodine Deficiency

    • Can lead to goiter (enlarged thyroid gland) and impaired cognitive function
    • During pregnancy, severe deficiency can cause cretinism, characterized by irreversible intellectual disabilities and physical stunting

    Iodine Toxicity

    • Excessive iodine intake can also cause thyroid enlargement

    Sodium, Chloride, Potassium & Water balance

    • Cells concentrate sodium and chloride outside their boundaries, while potassium and other ions are inside their boundaries
    • Cells regulate water inside and outside their boundaries by maintaining specific amounts of sodium and potassium
    • Healthy kidneys precisely regulate the body's sodium and water levels, filtering out excess sodium and returning the exact amount the body needs to the bloodstream.
    • The body can't compensate for sudden, significant fluid and electrolyte losses, requiring medical intervention

    Major Minerals

    • The major minerals are: calcium, chloride, magnesium, phosphorus, potassium, sodium, and sulfur.
    • The major minerals are present and needed in larger amounts in the body than trace minerals.
    • Recommended intakes for the major minerals are in hundreds of milligrams or grams.
    • Calcium and potassium are considered nutrients of public health concern because underconsumption is linked to chronic diseases.
    • Sodium is overconsumed by most people.
    • All major minerals influence the body's fluid balance, with sodium, chloride, and potassium being most noted for their role.
    • Sodium, potassium, calcium, and magnesium are critical to nerve transmission and muscle contractions.
    • Phosphorus and magnesium are involved in energy metabolism.
    • Calcium, phosphorus, and magnesium contribute to bone structure.
    • Sulfur helps determine the shape of proteins.

    Calcium

    • Calcium is the most abundant mineral in the body.
    • 99% of the body's calcium is stored in bones and teeth, while the other 1% circulates in body fluids as ionized calcium.
    • Calcium is a key component of bone structure.
    • Calcium recommendations vary by age and life stage:
      • Adolescents (high bone growth): 1300 mg/day
      • Adults aged 19 to 50: 1000 mg/day
      • Women over age 50 and all adults over age 70: 1200 mg/day
    • Many people in the US do not consume enough calcium.
    • Dairy products are the richest sources of calcium, with one cup of milk providing about 300 mg.
    • Cheese also contains substantial amounts of calcium.
    • Other good sources of calcium include:
      • Calcium-fortified foods (juice, milk, cereals)
      • Certain leafy green vegetables (beet greens, bok choy, broccoli, kale, mustard greens, rutabaga, turnip greens)
      • Calcium-rich mineral water
    • Spinach and Swiss chard, while appearing to be calcium-rich, contain binders that limit calcium absorption.
    • Calcium absorption varies by age and physiological state:
      • Infants and children: absorb up to 60%
      • Pregnant women: absorb about 50%
      • Other adults: absorb about 20-30%
    • While supplements can help bridge the gap between dietary intake and recommendations, it is generally better to obtain calcium from food sources.
    • Foods provide additional nutrients and may enhance calcium absorption.
    • Some individuals absorb calcium more efficiently from dairy products than supplements.

    Phosphorus

    • The second most abundant mineral in the body.
    • About 85% is found in bones and teeth, combined with calcium.
    • Found in all body tissues as part of the body's buffer system (phosphoric acid).
    • Part of DNA and RNA, necessary for all growth.
    • Key roles in the transfer of energy during cellular metabolism.
    • Phosphorus-containing lipids (phospholipids) help transport other lipids in the blood.
    • Phospholipids are also key parts of cell membranes.
    • Animal protein is the best source of phosphorus, as animal cells are abundant in phosphorus.
    • Milk and cheese are other rich sources.
    • Diets with enough energy and protein also supply enough phosphorus.
    • Dietary deficiencies are rare.

    Magnesium

    • Magnesium is a vital mineral involved in bone mineralization, protein production, enzyme activity, muscle contraction, and nerve impulse transmission.
    • Involved in hundreds of enzymes and other cellular functions.
    • Sources: foods from animal sources such as meat, fish, poultry, eggs, and milk.
    • Deficiency symptoms include low blood calcium, muscle cramps, confusion, seizures, bizarre movements, hallucinations, difficulty swallowing, and growth failure in children.
    • Toxicity is only from non-food sources and can cause diarrhea, nausea, abdominal cramps, acid-base imbalance, and potassium depletion.
    • Sources: nuts, legumes, whole grains, dark green vegetables, seafood, chocolate, and cocoa.

    Sulfate

    • The oxidized form of sulfur found in foods and water
    • Necessary for synthesizing important sulfur-containing compounds, such as sulfur-containing amino acids.
    • Sulfur containing amino acids are important for protein structure.
    • Skin, hair, and nails contain rigid proteins with high sulfur content.
    • A component of certain amino acids, the vitamins biotin and thiamin, and the hormone insulin.
    • Stabilizes protein shape by forming sulfur-sulfur bridges.
    • No recommended intake, and deficiencies are unknown.
    • Protein deficiency would likely occur before a sulfate deficiency.
    • Toxicity would only occur from excess sulfur amino acid consumption, which can suppress growth.
    • Sources: all protein-containing foods such as meat, fish, poultry, eggs, milk, legumes, and nuts.

    Iron

    • Iron is a component of hemoglobin in red blood cells and myoglobin in muscle cells, helping transport oxygen.
    • Iron is vital for energy production, cell growth, and the synthesis of amino acids, hormones, and neurotransmitters.
    • The body tightly regulates iron absorption and storage to ensure adequate levels while preventing toxicity.
    • Special proteins transport and store iron, and the hormone hepcidin plays a central role in maintaining iron balance.
    • Iron deficiency is the most common nutrient deficiency worldwide, prevalent in preschool children, pregnant women, toddlers, adolescent females, and women of childbearing age.
    • The main cause of iron deficiency is inadequate intake from iron-poor food choices or blood loss.
    • Iron deficiency develops in three stages, assessed using laboratory tests:
      • Stage 1: Depleted iron stores, reflected by low serum ferritin levels.
      • Stage 2: Decreased transport iron, with low serum iron and high transferrin levels.
      • Stage 3: Limited hemoglobin production, leading to low hemoglobin and hematocrit values and accumulation of erythrocyte protoporphyrin.
    • Iron-deficiency anemia occurs when severe iron depletion results in low hemoglobin concentration, leading to fatigue, weakness, headaches, apathy, pallor, and poor cold tolerance.
    • Some iron-deficient individuals exhibit pica, a craving for nonfood substances like ice, chalk, starch, and clay.
    • It is crucial to consult a physician for diagnosis rather than self-diagnosing iron deficiency and taking supplements, as iron deficiency can mask underlying medical conditions.
    • Iron overload, often caused by hemochromatosis, a genetic disorder, can lead to tissue damage, infections, and increased risks of diabetes, liver cancer, heart disease, and arthritis.
    • Rapid ingestion of large amounts of iron, particularly from supplements, can be fatal, especially in young children. Keep iron supplements out of reach of children.
    • Iron needs vary depending on age and gender. Women of childbearing age have higher iron needs (18 mg/day) than men (8 mg/day).
    • Food Sources:
      • Heme Iron: Found in meat, poultry, and fish, it is more absorbable than nonheme iron.
      • Nonheme Iron: Found in both plant and animal foods.
    • Factors Affecting Absorption:
      • MFP factor (found in meat, fish, and poultry) and vitamin C enhance iron absorption, while tannins, calcium, and phytates inhibit it.

    Iodine

    • The ocean is the primary source of iodine.
    • Iodized salt, seafood, and foods grown in iodine-rich soil are good dietary sources.

    Copper

    • Copper is a component of various enzymes involved in iron absorption and utilization, collagen synthesis, wound healing, and nerve function.
    • Deficiency is rare but can occur in premature infants, malnourished infants, and individuals with high zinc intakes.
    • Copper toxicity is usually associated with genetic disorders.
    • Organ meats, legumes, whole grains, seafood, nuts, and seeds are good sources of copper.

    Manganese

    • Manganese acts as a cofactor for numerous enzymes involved in various metabolic processes, including bone formation.
    • Manganese deficiency is rare in humans.
    • Toxicity can occur from inhaling manganese dust, primarily affecting the nervous system.
    • Nuts, whole grains, leafy green vegetables, and tea are good sources of manganese.

    Fluoride

    • Fluoride is essential for the mineralization of bones and teeth.
    • It helps form fluorapatite, which strengthens teeth and makes them resistant to decay.
    • Deficiency increases the risk of dental caries (tooth decay).
    • Excessive fluoride intake, especially during tooth development, can cause fluorosis, resulting in white specks or staining on teeth.
    • Drinking water (fluoridated or naturally containing fluoride), processed beverages made with fluoridated water, fluoride toothpastes, and certain foods like fish and tea are sources of fluoride.

    Chromium

    • Chromium enhances insulin action and plays a role in carbohydrate and lipid metabolism.
    • Deficiency is unlikely but can lead to impaired glucose tolerance and a diabetes-like condition.
    • Unrefined foods like liver, brewer's yeast, whole grains, nuts, and cheeses are good sources of chromium.

    Other Trace Minerals

    • Molybdenum: an essential trace mineral that functions as part of several enzymes. Deficiencies and toxicities are unknown.
    • Nickel, silicon, cobalt, and boron are known or suspected to play roles in various bodily functions.

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