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Questions and Answers
Which of the following best describes acute inflammation?
What is a distinguishing feature of granulomatous inflammation?
Which chemical substances mediate the vascular and cellular reactions of inflammation?
Which of the following is NOT considered a cardinal sign of inflammation?
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In chronic inflammation, which cell types are predominantly present?
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What type of inflammation is associated with foreign bodies and persistent infections?
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Which of the following conditions is an example of acute inflammation?
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Which cellular response marks the transition from blood to tissues during inflammation?
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What is a common trigger for acute inflammatory responses?
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What is the characteristic duration of acute inflammation?
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Study Notes
Inflammation Definition
- Inflammation is a response of living tissue to harmful agents.
- It involves vascular changes, leukocyte infiltration, and systemic reactions.
- It is a common pathologic process seen in many diseases.
Types of Inflammation
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Acute inflammation:
- Rapid onset (seconds or minutes).
- Short duration (minutes, hours, or days).
- Characterized by fluid and plasma protein exudation.
- Predominantly neutrophil leukocyte emigration.
- Examples: Acute appendicitis, cholecystitis
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Chronic inflammation:
- Insidious onset.
- Longer duration.
- Histologically associated with lymphocytes, macrophages, and plasma cells.
- Blood vessel and fibroblast proliferation.
- Example: Chronic prostatitis
Granulomatous Inflammation
- A specific type of chronic inflammation.
- Characterized by activated macrophages known as epithelioid histiocytes.
- Collections of epithelioid macrophages are called granulomas.
- Associated with foreign bodies, persistent infections (e.g., mycobacteria), and diseases of unclear origin (e.g., sarcoidosis).
Cardinal Signs of Inflammation
- Rubor (Redness)
- Calor (Hotness)
- Tumor (Swelling)
- Dolor (Pain)
- Functio laesa (Loss of function)
Chemical Mediators of Inflammation
- Both acute and chronic inflammation involve tissue necrosis.
- Vascular and cellular reactions are mediated by chemical substances (mediators) derived from plasma proteins or cells.
- These mediators amplify the inflammatory response and influence its evolution.
Action of Inflammatory Cells
- Leukocytes migrate and undergo diapedesis (passage through blood vessel walls) during inflammation.
- The presence of numerous white blood cells (WBC) indicates inflammation.
- Example: Chronic prostatitis, showing a normal prostate on the left and an inflamed gland with lymphocytes on the right.
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Description
Explore the definitions and classifications of inflammation through this informative quiz. Learn about acute, chronic, and granulomatous inflammation, their characteristics, causes, and examples. Test your understanding and deepen your knowledge of this important biological process.
