Podcast
Questions and Answers
Which drugs are administered as posttransplantory immunosuppressants to prevent acute transplant rejection?
Which drugs are administered as posttransplantory immunosuppressants to prevent acute transplant rejection?
- Cytostatics
- Glucocorticoids (correct)
- Antibodies
- Drugs acting on immunophilins
Which group of drugs primarily suppresses cell-mediated immunity?
Which group of drugs primarily suppresses cell-mediated immunity?
- Glucocorticoids (correct)
- Antibodies
- Cytostatics
- Drugs acting on immunophilins
Which group of drugs is used to suppress various allergic, inflammatory, and autoimmune disorders?
Which group of drugs is used to suppress various allergic, inflammatory, and autoimmune disorders?
- Drugs acting on immunophilins
- Antibodies
- Cytostatics
- Glucocorticoids (correct)
Which drugs act by inhibiting gene expression of cytokines including Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, IL-6, IL-8?
Which drugs act by inhibiting gene expression of cytokines including Interleukin 1 (IL-1), IL-2, IL-3, IL-4, IL-5, IL-6, IL-8?
Which group of drugs do not prevent an infection and inhibit later reparative processes?
Which group of drugs do not prevent an infection and inhibit later reparative processes?
Flashcards
What are glucocorticoids used for?
What are glucocorticoids used for?
Glucocorticoids are a class of drugs that are used as post-transplant immunosuppressants to prevent acute transplant rejection.
How do glucocorticoids affect the immune system?
How do glucocorticoids affect the immune system?
Glucocorticoids primarily suppress cell-mediated immunity, which is a part of the immune system that targets specific cells.
What conditions are treated with glucocorticoids?
What conditions are treated with glucocorticoids?
Glucocorticoids are used to treat various allergic, inflammatory, and autoimmune disorders.
How do glucocorticoids work at the molecular level?
How do glucocorticoids work at the molecular level?
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What's a potential downside of using glucocorticoids?
What's a potential downside of using glucocorticoids?
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Study Notes
Posttransplant Immunosuppressants
- Drugs like corticosteroids, calcineurin inhibitors (e.g., cyclosporine, tacrolimus), and antimetabolites (e.g., azathioprine, mycophenolate mofetil) are commonly used.
- These medications are crucial for preventing acute transplant rejection in organ transplant recipients.
Cell-Mediated Immunity Suppressants
- Calcineurin inhibitors primarily suppress cell-mediated immunity.
- They block T-cell activation, which is essential in the immune response to transplanted organs.
Drugs for Allergic, Inflammatory, and Autoimmune Disorders
- Corticosteroids are utilized to manage various allergic reactions, inflammatory responses, and autoimmune diseases.
- These are effective in reducing inflammation and modulating immune responses.
Cytokine Gene Expression Inhibitors
- Drugs such as glucocorticoids inhibit the expression of multiple cytokines, including IL-1, IL-2, IL-3, IL-4, IL-5, IL-6, and IL-8.
- This action diminishes inflammation and prevents activation of the immune system.
Non-Infection Preventive Immunosuppressants
- Immunosuppressants like mycophenolate mofetil do not prevent infections but may hinder the body’s reparative processes post-transplant.
- Their use involves balancing the risk of infection with the need to prevent rejection, emphasizing careful monitoring.
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Description
Test your knowledge of Immunosuppressive Drugs Classification with this quiz. Learn about the different groups of immunosuppressive drugs, including glucocorticoids, cytostatics, antibodies, drugs acting on immunophilins, and other drugs.
