Dose Optimization of Immunosuppressive Drugs Quiz
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Questions and Answers

What is the purpose of therapeutic drug monitoring (TDM) of immunosuppressant blood levels?

  • To limit the risk of over or underexposure to the drugs (correct)
  • To promote acute rejection of solid organ transplantation
  • To decrease the variability in pharmacological response
  • To increase the risk of overexposure to the drugs

    • What is a potential consequence of underexposure to immunosuppressive drugs?

  • Decreased variability in pharmacological response
  • Lack of efficacy in preventing acute rejection (correct)
  • Improved therapeutic monitoring
  • Decreased risk of toxicity

    • Why is variability in pharmacological response a concern with immunosuppressive drugs?

  • It only causes overexposure and toxicity
  • It reduces the need for therapeutic drug monitoring
  • It has no impact on the effectiveness of the drugs
  • It may cause underexposure leading to lack of efficacy (correct)

    • What is a relevant line of investigation in pharmacology related to immunosuppressive drugs?

    <p>Improvements in therapeutic monitoring (A)</p> Signup and view all the answers

    Despite extensive use of TDM, why does the incidence of acute rejection remain high?

    <p>Acute cellular rejection can occur even within therapeutic blood levels (B)</p> Signup and view all the answers

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