Podcast
Questions and Answers
Which phase of the cell cycle is primarily affected by Cyclosporin?
Which phase of the cell cycle is primarily affected by Cyclosporin?
- G0 and G1 phase (correct)
- M phase
- G2 phase
- S phase
What is the primary mechanism of action of Tacrolimus?
What is the primary mechanism of action of Tacrolimus?
- Inhibition of lymphokine production
- Inhibition of release of IL-2
- Inhibition of phosphatase activity of calcineurin (correct)
- Stimulation of T-cell activation
Which of the following adverse effects is common to both Cyclosporin and Tacrolimus?
Which of the following adverse effects is common to both Cyclosporin and Tacrolimus?
- Anaphylaxis
- Nephrotoxicity
- Hepatotoxicity
- All of the above (correct)
Which drug is used topically for severe atopic dermatitis?
Which drug is used topically for severe atopic dermatitis?
What is the primary mechanism of action of Sirolimus?
What is the primary mechanism of action of Sirolimus?
What is the result of Temisirolimus binding to FKBP-12?
What is the result of Temisirolimus binding to FKBP-12?
Which of the following adverse drug reactions is associated with polysorbate 80 in the formulation of Temsirolimus?
Which of the following adverse drug reactions is associated with polysorbate 80 in the formulation of Temsirolimus?
What is the mechanism of action of Pimecrolimus?
What is the mechanism of action of Pimecrolimus?
Which immunosuppressive drug is converted to its active form, mycophenolic acid, after absorption?
Which immunosuppressive drug is converted to its active form, mycophenolic acid, after absorption?
Which of the following immunosuppressive drugs is commonly used in combination with Cyclosporine and Corticosteroids for renal, hepatic, and cardiac transplants?
Which of the following immunosuppressive drugs is commonly used in combination with Cyclosporine and Corticosteroids for renal, hepatic, and cardiac transplants?
What is the effect of high fat on the absorption of Sirolimus oral solution?
What is the effect of high fat on the absorption of Sirolimus oral solution?
Which of the following immunosuppressive drugs is metabolized by glucuronidation?
Which of the following immunosuppressive drugs is metabolized by glucuronidation?
