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Questions and Answers
What describes artificial active immunity?
What describes artificial active immunity?
What is a result of immunisation against a weakened microorganism?
What is a result of immunisation against a weakened microorganism?
What happens when a person at risk doesn't develop their own immune response?
What happens when a person at risk doesn't develop their own immune response?
Which statement about antibodies is correct?
Which statement about antibodies is correct?
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What occurs when the immunity from a vaccination runs out?
What occurs when the immunity from a vaccination runs out?
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What is a key feature of memory cells in the immune system?
What is a key feature of memory cells in the immune system?
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Which of the following describes a passive immunity approach?
Which of the following describes a passive immunity approach?
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How does the body respond after being exposed to the same pathogen multiple times?
How does the body respond after being exposed to the same pathogen multiple times?
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What is the primary aim of the Immunology 2 module?
What is the primary aim of the Immunology 2 module?
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Which of the following is NOT a type of immunity discussed in the Immunology 2 module?
Which of the following is NOT a type of immunity discussed in the Immunology 2 module?
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What does passive immunity primarily involve?
What does passive immunity primarily involve?
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Which of the following best describes natural active immunity?
Which of the following best describes natural active immunity?
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Which of the following resources is NOT recommended for consolidating learning in Immunology 2?
Which of the following resources is NOT recommended for consolidating learning in Immunology 2?
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What are the two main types of immunity discussed in Immunology 2?
What are the two main types of immunity discussed in Immunology 2?
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What is an example of artificial passive immunity?
What is an example of artificial passive immunity?
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Which aspect of immunology is emphasized in the self-assessment quiz?
Which aspect of immunology is emphasized in the self-assessment quiz?
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Study Notes
Immunology 2
- Tutor: Ms P Lazarou
- Module: Biomedical Sciences
- Learning Outcomes (GDC 1.1): Apply dental therapy and hygiene principles derived from biomedical, behavioral, and material sciences. Develop knowledge in immunology.
Assessment
- Formative: Quiz
- Summative: Questions integrated into the Biomedical Sciences assessment.
Immunology 2 Tasks
- Task 1: Read and complete a task based on the article "Antibody-mediated vs cell-mediate immunity" (pages 5-8). Authors: Warrington, Watson, Kim, Romana, and Antonetti.
- Task 2: Complete a self-assessment quiz on antibody-mediated and cell-mediated immunity.
Intended Learning Outcomes
- Review antibody-mediated and cell-mediated immunity using appropriate resources and a self-assessment quiz.
- Define and recognize the differences between antibody-mediated and cell-mediated immunity.
- Recognize and explain passive and active immunization.
Antibody-mediated and Cell-mediated Immunity
- Consolidation: Learning reinforced via YouTube videos.
-
YouTube Resources:
- The Cellular Immune Response: https://www.youtube.com/watch?v=oUpcRfpEh3c
- Antigen Processing and Presentation: https://www.youtube.com/watch?v=Bgd1qxQ0Dh4&feature=emb_logo
Humoral vs Cellular Immunity (Diagram)
- Humoral immunity focuses on extracellular microbes (e.g., bacteria). B lymphocytes produce secreted antibodies. Mechanisms include neutralization, lysis, and phagocytosis.
- Cellular immunity targets intracellular microbes (e.g., viruses). Antigen-presenting cells activate helper T cells to proliferate and activate effector cells (macrophages & cytotoxic T cells) leading to lysis (destruction) of infected cells.
Passive and Active Immunity
-
Passive Immunity: Antibodies transferred from an immune person to a non-immune person.
- Natural Passive: e.g., mother's antibodies through placenta/breast milk
- Artificial Passive: e.g., snake antitoxin, immunoglobulin transplant.
-
Active Immunity: Antibodies developed in response to infection or vaccination.
- Natural Active: Antibodies develop after infection.
- Artificial Active: Antibodies develop after vaccination.
Immunisation
- Artificial Active Immunity: Antibodies develop after vaccine administration.
- Mechanism: Immunological memory. Weakened/killed microorganism exposure induces a specific immune reaction. Subsequent infections trigger a faster and stronger immune response. Antibodies attach to specific antigen surface structures activating the complement system (See immunology 1).
How Vaccines Work
- A small amount of a harmless form of a disease is introduced to the body.
- The body produces antibodies to combat this harmless form of the disease.
- Repeated exposure (the disease) triggers the same antibody response (and immunological memory) thereby preventing the disease.
References
- Article: Warrington, R., Watson, W., Kim, H., Romana, F., & Antonetti, F. An introduction to immunology and immunopathology. (Pages 5-8)
- General Immunology Text: McMahon, R., & Sloan, P. Essentials of Pathology for Dentistry. London: Harcourt Publishers, 2000.
- Allergy: https://www.immunology.org/public-information/bitesized-immunology/immune-dysfunction/allergy
- Additional Sources: Listed in the reference slide.
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Description
Test your understanding of antibody-mediated and cell-mediated immunity in this quiz. Based on the article by Warrington et al., this assessment will help you define, recognize, and explain key concepts of immunology. Enhance your biomedical sciences knowledge and prepare for your summative assessment.
