Immunology 2 medium

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What are the key variances between antibody-mediated immunity and cell-mediated immunity?

Antibody-mediated immunity is primarily effective against intracellular pathogens.

Cell-mediated immunity does not require recognition of antigens.

Cell-mediated immunity involves T cells that directly attack infected cells. (correct)

Only antibody-mediated immunity involves the use of antibodies.

Which of the following best describes natural passive immunity?

Immunity acquired from a mother’s antibodies through breastfeeding. (correct)

Immunity developed through direct exposure to an antigen.

Immunity gained from the administration of a vaccine.

Immunity gained from exposure to disease in a clinical setting.

Which statement accurately defines artificial active immunity?

Immunity gained from the environment.

Immunity developed by natural infection.

Immunity established through vaccination. (correct)

Immunity provided through direct infusion of antibodies.

What is the primary role of T cells in cell-mediated immunity?

To directly target and kill infected or cancerous cells. Signup and view all the answers

How does artificial passive immunity differ from natural passive immunity?

Artificial passive immunity is transferred therapeutically, not through natural means. Signup and view all the answers

Which process is primarily associated with antibody-mediated immunity?

Production of antibodies by B cells. Signup and view all the answers

What does the self-assessment quiz aim to achieve for students in this module?

To reinforce knowledge of antibody-mediated and cell-mediated immunity. Signup and view all the answers

Which learning outcome pertains specifically to the understanding of immunization?

Recognize and explain passive and active immunization. Signup and view all the answers

What triggers the production of antibodies in artificial active immunity?

Immunization with a vaccine Signup and view all the answers

What describes the role of antibodies in the immune response?

They activate the complement system. Signup and view all the answers

What is the primary characteristic of an immune response following vaccination?

Memory development for future exposure Signup and view all the answers

How does the body respond to subsequent infections from the same pathogen after vaccination?

With a stronger and faster defensive reaction Signup and view all the answers

Which factor can limit the effectiveness of passive immunity?

Short duration of acquired antibodies Signup and view all the answers

In the context of passive immunity, what is the main method of acquiring antibodies?

Transfer from an immune to a non-immune person Signup and view all the answers

What is the characteristic of the specific immune response to an antigen?

It involves memory and can recognize the antigen upon re-exposure. Signup and view all the answers

What is a potential reason for using antiserum in immunotherapy?

To provide immediate, but temporary protection Signup and view all the answers

Study Notes

Immunology 2

Module: Biomedical Sciences
Tutor: Ms P Lazarou
GDC Learning Outcomes
- Aim to apply principles of biomedical, behavioural, and material science to the dental therapy and dental hygienist practice.
- Develop knowledge of immunology.

Assessment

Formative: Quiz
Summative: Questions incorporated in Biomedical Sciences assessment.

Immunology 2 Content

Read and complete a task from the article "Antibody-mediated vs cell-mediate immunity" (pages 5-8) by Warrington et al.
Complete a self-assessment quiz on antibody-mediated and cell-mediated immunity

Intended Learning Outcomes: Immunology 2

Review antibody-mediated and cell-mediated immunity by reading materials and completing a quiz.
Define and recognise the variations between antibody-mediated and cell-mediated immunity.
Recognise and explain passive and active immunisation.

Antibody-mediated and cell-mediated immunity

Consolidation of learning, using:
- YouTube video: "The Cellular Immune Response" (link provided).
- YouTube video: "ANTIGEN PROCESSING AND PRESENTATION" (link provided).

Humoral and Cellular Immunity (Diagram Description)

Humoral Immunity: Deals with extracellular microbes (e.g., bacteria). B lymphocytes secrete antibodies that neutralize, lyse (with complement), and phagocytose the microbes
Cellular Immunity: Targets intracellular microbes (e.g., viruses). Antigen-presenting cells (APCs) present antigens to T-cells which then activate effector cells. These effector cells, such as macrophages and cytotoxic T cells, destroy the infected cells.

Passive and Active Immunity

Passive Immunity:
- Natural: Passed from mother to child through placenta/breast milk
- Artificial: Transfer of antibodies therapeutically (e.g., snake antivenom); transfer of immune cells or antibodies to a non-immune person. Short-duration; risk of running out of immunity.
Active Immunity:
- Natural: Develops after exposure to infection.
- Artificial: Develops after vaccination; specific antibodies against a specific agent. Long-lasting immunity with memory response, meaning the antigen is remembered and subsequent encounters result in faster, stronger responses.

Immunisation

Artificial Active Immunity: antibodies develop after vaccination/immunization.
How it Works:
- Introduces weakened/killed microorganisms to trigger an immunological memory.
- Subsequent infections elicit a stronger and faster response.
- Antibody and/or cell reaction to specific surface structures on the antigen, activating the complement system (refer to Immunology 1 for more details).

How Vaccines Work

Small amount of harmless form of a disease is introduced.
Body produces antibodies to fight it
Subsequent exposure results in immunity because the body already recognizes and has antibodies to the disease.

References

Mentioned article by Warrington et al., book by McMahon & Sloan, Allergy information from the British Society for Immunology, and reports on autoimmune awareness from Garcia P.
Additional reference provided on immunodeficiency from the British Society for Immunology.
Other reference given on autoimmune diseases from Hindawi.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Description

Test your understanding of antibody-mediated and cell-mediated immunity with this quiz from Biomedical Sciences. Engage with the material from Warrington et al. and enhance your knowledge of immunological concepts relevant to dental therapy. Perfect for self-assessment and concept reinforcement.