Immunology 2: Antibody vs Cell-Mediated Immunity
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Questions and Answers

What characterizes artificial active immunity?

  • Immunity develops after exposure to an antigen
  • Immunity results from the transfer of antibodies from another person
  • Immunity is temporary and short-lived
  • Immunity is achieved through the administration of a vaccine (correct)

What is the primary function of immunoglobulins?

  • To produce long-lasting memory cells
  • To enhance the activity of killer T-cells
  • To identify and neutralize foreign agents (correct)
  • To provide immediate immunity to a new pathogen

What does the immune response after subsequent infections entail?

  • No significant difference from the first exposure
  • The production of a different type of antibody
  • A stronger and faster defensive reaction (correct)
  • A slower reaction with fewer antibodies

For which scenario would antitoxin be primarily used?

<p>To provide immediate immunity against a disease (C)</p> Signup and view all the answers

What does immunization aim to achieve?

<p>The production of antibodies against specific antigens (A)</p> Signup and view all the answers

How is immunological memory established?

<p>By retaining information about specific antigens (A)</p> Signup and view all the answers

What happens when the body is at risk of losing immunity?

<p>The body fails to respond effectively to pathogens (A)</p> Signup and view all the answers

What role do antibodies play in the immune response?

<p>They activate the complement system (D)</p> Signup and view all the answers

What is the primary focus of the immunology subject in the context of dental therapy?

<p>Applying biomedical and behavioral sciences principles (D)</p> Signup and view all the answers

Which of the following is an example of natural passive immunity?

<p>Antibodies passed from mother to child (C)</p> Signup and view all the answers

What distinguishes active immunity from passive immunity?

<p>Active immunity involves the body's own production of antibodies (D)</p> Signup and view all the answers

Which statement accurately describes artificial active immunity?

<p>It results from the administration of a vaccine that stimulates antibody production (A)</p> Signup and view all the answers

In which learning activity are students expected to review antibody-mediated and cell-mediated immunity?

<p>Reading assigned articles and completing a self-assessment quiz (D)</p> Signup and view all the answers

What is the importance of antigen processing and presentation in the immune response?

<p>It helps in the efficient activation of T-cells (C)</p> Signup and view all the answers

Which type of immunity is exemplified by the transfer of antibodies from one individual to another, usually therapeutically?

<p>Artificial passive immunity (D)</p> Signup and view all the answers

What is the main objective of the self-assessment quiz related to immunology?

<p>To assess knowledge on immunology and its applications (C)</p> Signup and view all the answers

Flashcards

Antibody-mediated immunity

An immune response that involves antibodies produced by B cells to neutralize pathogens.

Cell-mediated immunity

An immune response that involves T cells directly attacking infected cells.

Passive immunity

Acquiring immunity through pre-formed antibodies from another source.

Active immunity

Developing immunity through the body's own immune response to a pathogen.

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Natural passive immunity

Passive immunity acquired naturally, such as from a mother to a baby.

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Artificial passive immunity

Passive immunity acquired through medical intervention, like an antibody injection.

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Natural active immunity

Active immunity developed naturally after contracting a disease.

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Artificial active immunity

Active immunity developed through vaccination.

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Snake Antitoxin

A treatment given to neutralize venom from snake bites.

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Response to Infection

The body's reaction to an invading pathogen.

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Response to Vaccination

The body's immune system building defenses against a disease.

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Immunoglobulin (transplant)

Antibodies or sensitized cells transferred to prevent infection or disease.

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Artificial Active Immunity

Developing antibodies after receiving a vaccine.

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Immunological Memory

The ability of the immune system to remember previous pathogens.

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Vaccine

A weakened or killed microorganism that triggers an immune response without causing the full disease.

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Antigen

A substance that triggers an immune response.

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Study Notes

Immunology 2

  • Module: Biomedical Sciences
  • Tutor: Ms. P. Lazarou
  • Learning Outcomes:
    • Apply dental therapy and hygiene principles derived from biomedical, behavioural, and materials sciences.
    • Develop knowledge in immunology.

Assessment

  • Formative: Quiz
  • Summative: Questions integrated into Biomedical Sciences assessment.

Immunology 2 - Specific Tasks

  • Task 1: Read and complete a task from the article "Antibody-mediated vs cell-mediated immunity," pages 5-8. Article authors are referenced.
  • Task 2: Complete a self-assessment quiz on antibody-mediated and cell-mediated immunity.

Intended Learning Outcomes

  • Review antibody-mediated and cell-mediated immunity using resources and a self-assessment quiz.
  • Define and recognize differences between antibody-mediated and cell-mediated immunity.
  • Understand and explain passive and active immunization.

Antibody-mediated and Cell-mediated Immunity

  • Consolidation of learning is required.
  • Two YouTube videos linked as resources are included:
    • The Cellular Immune Response
    • Antigen Processing and Presentation

Humoral and Cellular Immunity

  • Diagrams illustrating humoral and cellular immunity are presented.
  • Humoral immunity involves extracellular microbes and B lymphocytes, resulting in antibody secretion and functions like neutralization, lysis, and phagocytosis.
  • Cellular immunity targets intracellular microbes (e.g. viruses) involving antigen-presenting cells, T cells, and subsequent cytokine release, leading to the lysis of infected cells.

Passive and Active Immunity

  • Passive immunity:
    • Natural passive: e.g., mother's antibodies through placenta/breast milk.
    • Artificial passive: transferring antibodies therapeutically (e.g., snake antitoxin, immunoglobulin).
  • Active immunity:
    • Natural active: developing antibodies from infection.
    • Artificial active: developing antibodies from vaccination.
  • Transfer of antibodies/sensitised cells from an immune person to a non-immune person. This is short-term and risky if own response is not developed.
  • Production of antibodies against a specific antigen after exposure. Memory is developed.

Immunisation

  • Artificial active immunity: antibodies develop after immunization/vaccination.
  • Immunological memory and development of a stronger immune response to subsequent infections.
  • Antibodies attach to specific surface structures on the antigen to activate the complement system.

How Vaccines Work

  • A small amount of a harmless form of a disease is introduced to the body.
  • The body produces antibodies to fight it off.
  • If the disease reappears, the antibodies are already present to prevent infection.

References

  • Articles and resources on immunology, immunopathology, and allergy from various websites and publications are listed.

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Description

This quiz focuses on the principles of antibody-mediated and cell-mediated immunity as part of the Immunology 2 curriculum in Biomedical Sciences. Students will engage with module resources and complete self-assessment tasks to differentiate between the two types of immunity, along with understanding passive and active immunization. Prepare to test your knowledge and application of these crucial concepts in immunology.

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