Immunology 2

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Questions and Answers

What is the primary purpose of antibodies developed in response to a vaccination?

  • To transfer antibodies from one person to another
  • To provide immediate protection against infection
  • To develop immunological memory (correct)
  • To react to any foreign antigen present

What describes the mechanism of artificial active immunity?

  • Administration of a vaccine leading to antibody production (correct)
  • Immediate production of antibodies in response to infection
  • Direct transfer of antibodies from mother to child
  • Short-term immunity from antigens

What occurs after an initial vaccination when re-exposed to the same pathogen?

  • Stronger and faster immune reaction (correct)
  • Weakened immune response
  • Delayed allergic reaction
  • Increased risk of infection

Which description best fits the short-duration immunity provided by antibodies transferred from an immune person?

<p>Temporary immunity with limited applications (C)</p> Signup and view all the answers

How does the immune system respond to a specific pathogen after vaccination?

<p>By producing specific antibodies that target the pathogen (B)</p> Signup and view all the answers

What does the activation of the complement system by antibodies achieve?

<p>Enhancement of the immune response against antigens (D)</p> Signup and view all the answers

Which situation illustrates the use of snake antitoxin?

<p>Immediate treatment after a snake bite (D)</p> Signup and view all the answers

What is a characteristic of primary immune response compared to secondary immune response?

<p>Slower and less specific (D)</p> Signup and view all the answers

What is the primary goal of the Immunology 2 module?

<p>To apply principles from various sciences to dental therapy and hygiene (C)</p> Signup and view all the answers

Which type of immunity is characterized by direct transfer of antibodies from mother to child?

<p>Natural passive immunity (C)</p> Signup and view all the answers

What distinguishes active immunity from passive immunity?

<p>Active immunity develops a response following exposure to an antigen. (C)</p> Signup and view all the answers

Which of the following statements about antibody-mediated immunity is correct?

<p>It relies on antibodies produced by B cells. (B)</p> Signup and view all the answers

What type of passive immunity is provided through medical interventions?

<p>Artificial passive immunity (D)</p> Signup and view all the answers

Which of the following is a key intended learning outcome of Immunology 2?

<p>To define and recognize variances between antibody-mediated and cell-mediated immunity. (B)</p> Signup and view all the answers

What resources are suggested for reviewing immune responses as part of this course?

<p>YouTube videos on cellular immune responses and antigen presentation (A)</p> Signup and view all the answers

Which type of immunity occurs when vaccinations are administered?

<p>Artificial active immunity (D)</p> Signup and view all the answers

Flashcards

Antibody-mediated immunity

Immune responses that involve antibodies in blood and lymph to target and neutralize pathogens. This involves B cells differentiating into plasma cells that secrete antibodies.

Cell-mediated immunity

Immune responses that directly involve T cells to kill infected cells or activate other immune components. Primarily involves cytotoxic T lymphocytes (CTLs) and helper T cells.

Active immunity

The body's natural immune response to an antigen, resulting in the development of antibodies. This can occur through infection or vaccination.

Passive immunity

The temporary immunity acquired through receiving pre-made antibodies, typically from a source like a mother or through an injection. It does not involve the body's own immune system.

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Natural passive immunity

Antibodies are passed from mother to fetus via the placenta or through breast milk, providing the newborn with initial immunity.

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Artificial passive immunity

This involves the administration of pre-made antibodies from another source, like an antivenom or antibody injection. It provides immediate, but temporary protection.

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Natural active immunity

This involves a person's own body producing antibodies in response to a natural infection, like getting the flu.

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Artificial active immunity

This involves introducing a weakened or dead form of the pathogen through vaccination, stimulating the immune system to create antibodies.

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Immunoglobulin - Transplant

A type of passive immunity where antibodies are injected into a person to provide immediate protection against a specific disease.

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Vaccination

Exposure to a weakened or killed pathogen, or its components, to stimulate an immune response and develop long-term immunity.

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Immunological Memory

The ability of the immune system to remember previous infections or vaccinations and mount a faster and more effective response to subsequent exposures.

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Immunisation

The process of introducing weakened or killed pathogens or their components into the body to stimulate an immune response and develop immunity.

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Antibody-Antigen Binding

Antibodies attach to specific structures on antigens, triggering a cascade of events that lead to the destruction of the invader.

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Complement System

A system of proteins that helps to destroy pathogens and trigger inflammation.

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Study Notes

Immunology 2 Module

  • Module is part of Biomedical Sciences
  • Tutor is Ms P Lazarou
  • Subject is focused on applying biomedical, behavioural, and material science principles to dental therapy and hygiene practices
  • Aims to develop knowledge and understanding of immunology
  • Learning outcomes include reviewing antibody-mediated and cell-mediated immunity, defining differences between the two types, and understanding passive and active immunization

Assessment

  • Formative assessment includes a quiz
  • Summative assessment involves questions integrated into the Biomedical Sciences eAssessment

Immunology 2: Tasks

  • Task 1: Read and complete a task on an article about antibody-mediated vs cell-mediated immunity (pages 5-8)
  • Task 2: Complete a self-assessment quiz on antibody-mediated and cell-mediated immunity

Intended Learning Outcomes

  • Review antibody-mediated and cell-mediated immunity by using resources and completing a self-assessment quiz
  • Define and understand variances between antibody-mediated and cell-mediated immunity
  • Recognise and explain passive and active immunizations

Antibody-mediated and Cell-mediated Immunity - Consolidation

  • The Cellular Immune Response (YouTube link included)
  • Antigen Processing and Presentation (YouTube link included)

Humoral vs Cellular Immunity

  • Diagrams showing differences in processes (Humoral and Cellular Immunity)
    • Humoral: extracellular microbes, B-lymphocytes, antibody secretion (neutralization, lysis(complement), phagocytosis)
    • Cellular: intracellular microbes, antigen presenting cell, helper T cells, T cell receptor, proliferation of effectors cells, lysis of infected cells

Passive and Active Immunity

  • Natural passive immunity: mother's antibodies via placenta/breast milk
  • Artificial passive immunity: transfer of antibodies (e.g., snake antitoxin, immunoglobulin)
  • Natural active immunity: antibodies developed in response to infections
  • Artificial active immunity: antibodies developed through vaccinations
  • Transfer of antibodies/sensitized cells from immune person to non-immune person; Short duration of protection; Risk of loss of immunity
  • Used when risk of infection is high/patient cannot generate their own immunity

Immunisation

  • Artificial Active Immunity: antibodies developed after immunization/vaccine administration
  • Immunological memory: a specific immune reaction induced against a weakened/killed microorganism; subsequent infections trigger a stronger and faster immune response via antibodies and/or cells; antibodies attach to antigens activating complement system

How Vaccines Work

  • Small amount of harmless form of a disease is introduced
  • Body produces antibodies to fight the introduced harmless form
  • If the real disease is encountered, the body already has the antibodies and is immune
  • YouTube link included

References

  • An introduction to immunology and immunopathology (article)
  • Essentials of Pathology for Dentistry (book)
  • Allergy related information (website link)
  • Report on autoimmune awareness/Juvenile Diabetes Research Foundation (website links)
  • Immunology website references on Immunodeficiency and related topics

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