Cyclobenzaprine (Flexeril) Flashcards
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Questions and Answers

What is the drug class of cyclobenzaprine (Flexeril)?

  • Centrally-acting muscle relaxant (correct)
  • Antidepressant
  • Opioid analgesic
  • Non-steroidal anti-inflammatory drug
  • What are the pharmacotherapeutics of cyclobenzaprine?

    Systemic muscle relaxant for acute musculoskeletal disorders, supportive for fibromyalgia and tetanus.

    Which of the following are contraindications for cyclobenzaprine?

  • Diabetes
  • Hyperthyroidism (correct)
  • Concurrent use of MAOIs (14 days) (correct)
  • Asthma
  • What precautions should be taken when using cyclobenzaprine?

    <p>Monitor for heart failure</p> Signup and view all the answers

    What are common adverse effects of cyclobenzaprine?

    <p>CNS depressant effects, dysrhythmias, seizures, myocardial infarction, ileus, angioedema.</p> Signup and view all the answers

    What are some side effects of cyclobenzaprine?

    <p>Anticholinergic effects, drowsiness, fatigue, abdominal pain, nausea, vomiting, dyspepsia, confusion, headache.</p> Signup and view all the answers

    What nursing implications need to be considered with cyclobenzaprine?

    <p>Coordinate with nonpharmacological therapies</p> Signup and view all the answers

    What should patients be taught regarding the use of cyclobenzaprine?

    <p>Take as prescribed, be aware of sedation effects, report severe headaches and weakness, do not stop abruptly.</p> Signup and view all the answers

    What are the pharmacodynamics of cyclobenzaprine?

    <p>Uncertain mechanism, probably acts at the brain stem, does not affect neuromuscular junction or muscle.</p> Signup and view all the answers

    Cyclobenzaprine is effective for spasticity of cerebral or spinal cord disease.

    <p>False</p> Signup and view all the answers

    What should be done if cyclobenzaprine has been taken for more than two weeks?

    <p>Taper the dosage.</p> Signup and view all the answers

    Tolerance occurs with prolonged use of cyclobenzaprine.

    <p>True</p> Signup and view all the answers

    Dependence is not a concern with the prolonged use of cyclobenzaprine.

    <p>False</p> Signup and view all the answers

    Study Notes

    Drug Class

    • Classified as a centrally-acting muscle relaxant and a CNS depressant.

    Pharmacotherapeutics

    • Used as a systemic muscle relaxant for acute musculoskeletal disorders.
    • Effective as supportive therapy for fibromyalgia and tetanus.

    Contraindications

    • Not suitable for patients with hyperthyroidism.
    • Avoid concurrent use with MAO inhibitors for at least 14 days.

    Precautions

    • Caution is required in individuals with heart failure or cardiac dysrhythmias.
    • Consider in cases of recent myocardial infarction or conduction disturbances.

    Adverse Effects

    • May lead to central nervous system depression, including altered heart rhythms.
    • Risk of seizures, myocardial infarction, and ileus.
    • Possible occurrence of angioedema.

    Side Effects

    • Anticholinergic effects: visual disturbances, urinary retention, constipation, and dry mouth.
    • Other side effects include drowsiness, fatigue, abdominal pain, nausea, dyspepsia, confusion, and headaches.

    Nursing Implications

    • Collaborate with nonpharmacological therapies like physical therapy and massage.
    • Schedule medication doses throughout the day to minimize interactions.
    • Monitor for synergistic effects with other CNS depressants.
    • Taper off medication if used for more than two weeks to prevent withdrawal.
    • Be aware of potential tolerance and physical dependence with long-term use.

    Patient Teaching

    • Instruct patients to follow prescription guidelines carefully.
    • Warn of potential sedation; refrain from driving until effect is known.
    • Encourage reporting of confusion, severe headache, sudden weakness, or respiratory/cardiac concerns.
    • Advise against abrupt cessation if taken for over two weeks.

    Pharmacodynamics

    • Mechanism of action is not fully understood; likely operates at the brain stem level.
    • Does not target the neuromuscular junction or muscle tissues directly.

    Ineffectiveness

    • Not recommended for treating spasticity related to cerebral or spinal cord diseases or cerebral palsy.

    Stopping Use

    • Medication should be tapered if used for more than two weeks to avoid withdrawal symptoms.

    Tolerance and Dependence

    • Both tolerance and dependence may develop with prolonged use of the drug.

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    Description

    Test your knowledge on Cyclobenzaprine, a common muscle relaxant, with these flashcards. Each card covers different aspects including drug class, pharmacotherapeutics, contraindications, and precautions. Perfect for students or healthcare professionals looking to enhance their understanding of this medication.

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