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Biochemistry LE 1: RBC Metabolism

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38 Questions

What is the primary function of hemoglobin in red blood cells?

To transport oxygen

What is the name of the pathway involved in the synthesis of glucose in red blood cells?

Hexose monophosphate shunt

What is the term for the disorders of red blood cell synthesis or function?

RBC disorders

What is the byproduct of heme degradation?

Bilirubin

What is the function of the glutathione system in red blood cells?

To reduce oxidative stress

What is the term for the precursor to heme?

Porphyrins

What is the enzyme involved in the degradation of hemoglobin?

Heme oxygenase

What percentage of total body weight is the total blood volume?

6 to 8%

What is the normal pH range of blood?

7.35 to 7.45

What is the specific gravity of blood?

1.035 to 1.075

What is the abbreviation for Bisphosphoglycerate?

2,3-BPG

What is the abbreviation for Erythropoietin?

EPO

What is the abbreviation for Glucose-6-phosphate-dehydrogenase?

G6PD

What is the abbreviation for Granulocyte macrophage colony-stimulating factor?

GM-CSF

What is the major component of red blood cells?

Hemoglobin

What is the pathway involved in the synthesis of glucose in red blood cells?

Hexose monophosphate shunt

What is the term for the disorders of the structure or function of hemoglobin?

Hemoglobinopathies

What is the byproduct of heme degradation in the red blood cell?

Bilirubin

What is the function of the glutathione system in red blood cells?

Antioxidant function

What is the term for the precursor to heme?

Porphyrin

What is the enzyme involved in the synthesis of glucose in red blood cells?

Glucose-6-phosphate-dehydrogenase

What is the primary function of the TCA cycle in red blood cells?

Energy production

Which of the following is involved in the synthesis of hemoglobin?

Delta-aminolevulinic acid synthase 1

What is the role of ROS in red blood cells?

Pro-oxidant function

What is the purpose of the Osmotic Fragility Test?

To assess red blood cell membrane integrity

What is the role of GSH in red blood cells?

Antioxidant function

What is the term for the disorders associated with bilirubin metabolism?

Jaundice

What is the percentage of total body weight that is comprised of total blood volume?

5-6%

What is the main function of the hexose monophosphate shunt?

To reduce NADP+

What is the role of cytochrome B5 reductase in red blood cells?

To reduce methemoglobin

What is the name of the pathway involved in the synthesis of heme?

Porphyrin pathway

What is the function of bilirubin in red blood cells?

To degrade heme

What is the term for the disorders of red blood cell structure or function?

RBC disorders

What is the role of glutathione in red blood cells?

To reduce oxidative stress

What is the term for the process of degrading heme in red blood cells?

Heme degradation

What is the average pH of blood?

7.40

What percentage of total body weight is comprised of total blood volume?

6 to 8%

What is the specific gravity range of blood?

1.035 to 1.075

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