Red Blood Cell Disorders Quiz

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Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

Aplastic anemia

Iron deficiency anemia

Megaloblastic anemia (correct)

Sideroblastic anemia

What causes microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

Ethanol

Zinc intoxication

Caffeine (correct)

Phenytoin

Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

Megaloblastic anemia

Aplastic anemia

Sideroblastic anemia (correct)

Iron deficiency anemia

What is the main function of oxyhemoglobin?

Binding to oxygen Signup and view all the answers

What represents hemoglobin after oxygen diffuses into tissues?

Deoxyhemoglobin Signup and view all the answers

What leads to methemoglobinemia?

Failure of metabolic mechanism for reducing heme iron back to the ferrous state Signup and view all the answers

Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

Ethanol Signup and view all the answers

In which type of anemia does the alteration in hemoglobin function occur?

Iron deficiency anemia Signup and view all the answers

What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

Carbaminohemoglobin Signup and view all the answers

What represents hemoglobin bound to oxygen?

Oxyhemoglobin Signup and view all the answers

Which of the following is a known cause of methemoglobinemia?

Benzocaine Signup and view all the answers

What effect does carbon monoxide have on the oxygen dissociation curve?

Causes a left shift Signup and view all the answers

Which enzyme defect is associated with oxidative hemolysis?

Glucose 6 phosphate dehydrogenase deficiency Signup and view all the answers

What is the cause of sickle-cell anemia?

Defective gene coding for hemoglobin S Signup and view all the answers

Which cells are the most important sources of cytokines?

Macrophages and T cells Signup and view all the answers

Which cells differentiate into myeloblasts or monoblasts?

Myeloid stem cells Signup and view all the answers

Which leukemias involve myeloblasts?

Myelocytic leukemia Signup and view all the answers

What is the primary cause of death in leukemia?

Internal hemorrhage and overwhelming infections Signup and view all the answers

Which of the following is a leukemogenic agent?

Benzene Signup and view all the answers

What effect do ethanol and glucocorticoids have on phagocytosis?

Impair phagocytosis Signup and view all the answers

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

Megaloblastic anemia Signup and view all the answers

What represents hemoglobin bound to oxygen?

Oxyhemoglobin Signup and view all the answers

What is the cause of microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

Caffeine Signup and view all the answers

What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

Carbaminohemoglobin Signup and view all the answers

Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

Tetracycline Signup and view all the answers

What represents hemoglobin after oxygen diffuses into tissues?

Deoxyhemoglobin Signup and view all the answers

What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

Sideroblastic anemia Signup and view all the answers

Which of the following is a known cause of methemoglobinemia?

Benzocaine Signup and view all the answers

What enzyme defect is associated with oxidative hemolysis?

Glucose 6 phosphate dehydrogenase deficiency Signup and view all the answers

Which leukemias involve myeloblasts?

Myelocytic leukemia Signup and view all the answers

What is the primary cause of death in leukemia?

Internal hemorrhage and overwhelming infections Signup and view all the answers

What represents hemoglobin bound to oxygen?

Oxyhemoglobin Signup and view all the answers

What effect do ethanol and glucocorticoids have on phagocytosis?

Impairment Signup and view all the answers

In which type of anemia does the alteration in hemoglobin function occur?

Sickle-cell anemia Signup and view all the answers

Which of the following is a leukemogenic agent?

Benzene Signup and view all the answers

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

Megaloblastic anemia Signup and view all the answers

What represents hemoglobin bound to oxygen?

Oxyhemoglobin Signup and view all the answers

What leads to methemoglobinemia?

Failure of control mechanisms for reducing heme iron back to the ferrous state Signup and view all the answers

What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

Sideroblastic anemia Signup and view all the answers

What effect do ethanol and zinc intoxication have on sideroblastic anemia?

Lead to defects in the synthesis of the porphyrin ring of the heme Signup and view all the answers

What effect does caffeine have on iron deficiency anemia?

Forms microcytic anemia with a decrease in the MCV Signup and view all the answers

What represents hemoglobin after oxygen diffuses into tissues?

Deoxyhemoglobin Signup and view all the answers

Which xenobiotic is capable of inducing oxidative injury to erythrocytes?

Naphthalene Signup and view all the answers

What is the primary cause of death in leukemia?

Internal hemorrhage and overwhelming infections Signup and view all the answers

Which leukemogenic agent is the only aromatic hydrocarbon known to cause leukemia?

Benzene Signup and view all the answers

Which cytokines hormonally stimulate leukopoiesis?

Interleukins and colony-stimulating factors Signup and view all the answers

What represents the process where all leukocytes originate from?

Hemocytoblasts Signup and view all the answers

What effect do ethanol and glucocorticoids have on phagocytosis?

Impairment Signup and view all the answers

Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

Sideroblastic anemia Signup and view all the answers

What leads to methemoglobinemia?

Benzocaine Signup and view all the answers

Red Blood Cell Disorders Quiz

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Questions and Answers

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

What causes microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

What is the main function of oxyhemoglobin?

What represents hemoglobin after oxygen diffuses into tissues?

What leads to methemoglobinemia?

Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

In which type of anemia does the alteration in hemoglobin function occur?

What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

What represents hemoglobin bound to oxygen?

Which of the following is a known cause of methemoglobinemia?

What effect does carbon monoxide have on the oxygen dissociation curve?

Which enzyme defect is associated with oxidative hemolysis?

What is the cause of sickle-cell anemia?

Which cells are the most important sources of cytokines?

Which cells differentiate into myeloblasts or monoblasts?

Which leukemias involve myeloblasts?

What is the primary cause of death in leukemia?

Which of the following is a leukemogenic agent?

What effect do ethanol and glucocorticoids have on phagocytosis?

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

What represents hemoglobin bound to oxygen?

What is the cause of microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

What represents hemoglobin after oxygen diffuses into tissues?

What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

Which of the following is a known cause of methemoglobinemia?

What enzyme defect is associated with oxidative hemolysis?

Which leukemias involve myeloblasts?

What is the primary cause of death in leukemia?

What represents hemoglobin bound to oxygen?

What effect do ethanol and glucocorticoids have on phagocytosis?

In which type of anemia does the alteration in hemoglobin function occur?

Which of the following is a leukemogenic agent?

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

What represents hemoglobin bound to oxygen?

What leads to methemoglobinemia?

What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

What effect do ethanol and zinc intoxication have on sideroblastic anemia?

What effect does caffeine have on iron deficiency anemia?

What represents hemoglobin after oxygen diffuses into tissues?

Which xenobiotic is capable of inducing oxidative injury to erythrocytes?

What is the primary cause of death in leukemia?

Which leukemogenic agent is the only aromatic hydrocarbon known to cause leukemia?

Which cytokines hormonally stimulate leukopoiesis?

What represents the process where all leukocytes originate from?

What effect do ethanol and glucocorticoids have on phagocytosis?

Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

What leads to methemoglobinemia?

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