Red Blood Cell Disorders Quiz
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Questions and Answers

Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

  • Aplastic anemia
  • Iron deficiency anemia
  • Megaloblastic anemia (correct)
  • Sideroblastic anemia
  • What causes microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

  • Ethanol
  • Zinc intoxication
  • Caffeine (correct)
  • Phenytoin
  • Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

  • Megaloblastic anemia
  • Aplastic anemia
  • Sideroblastic anemia (correct)
  • Iron deficiency anemia
  • What is the main function of oxyhemoglobin?

    <p>Binding to oxygen</p> Signup and view all the answers

    What represents hemoglobin after oxygen diffuses into tissues?

    <p>Deoxyhemoglobin</p> Signup and view all the answers

    What leads to methemoglobinemia?

    <p>Failure of metabolic mechanism for reducing heme iron back to the ferrous state</p> Signup and view all the answers

    Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

    <p>Ethanol</p> Signup and view all the answers

    In which type of anemia does the alteration in hemoglobin function occur?

    <p>Iron deficiency anemia</p> Signup and view all the answers

    What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

    <p>Carbaminohemoglobin</p> Signup and view all the answers

    What represents hemoglobin bound to oxygen?

    <p>Oxyhemoglobin</p> Signup and view all the answers

    Which of the following is a known cause of methemoglobinemia?

    <p>Benzocaine</p> Signup and view all the answers

    What effect does carbon monoxide have on the oxygen dissociation curve?

    <p>Causes a left shift</p> Signup and view all the answers

    Which enzyme defect is associated with oxidative hemolysis?

    <p>Glucose 6 phosphate dehydrogenase deficiency</p> Signup and view all the answers

    What is the cause of sickle-cell anemia?

    <p>Defective gene coding for hemoglobin S</p> Signup and view all the answers

    Which cells are the most important sources of cytokines?

    <p>Macrophages and T cells</p> Signup and view all the answers

    Which cells differentiate into myeloblasts or monoblasts?

    <p>Myeloid stem cells</p> Signup and view all the answers

    Which leukemias involve myeloblasts?

    <p>Myelocytic leukemia</p> Signup and view all the answers

    What is the primary cause of death in leukemia?

    <p>Internal hemorrhage and overwhelming infections</p> Signup and view all the answers

    Which of the following is a leukemogenic agent?

    <p>Benzene</p> Signup and view all the answers

    What effect do ethanol and glucocorticoids have on phagocytosis?

    <p>Impair phagocytosis</p> Signup and view all the answers

    Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    What represents hemoglobin bound to oxygen?

    <p>Oxyhemoglobin</p> Signup and view all the answers

    What is the cause of microcytic anemia with a decrease in the mean corpuscular volume (MCV)?

    <p>Caffeine</p> Signup and view all the answers

    What is the result of alteration in hemoglobin function known as when hemoglobin is bound to carbon dioxide?

    <p>Carbaminohemoglobin</p> Signup and view all the answers

    Which xenobiotic can represent a cause of destruction or inhibition of red bone marrow in aplastic anemia?

    <p>Tetracycline</p> Signup and view all the answers

    What represents hemoglobin after oxygen diffuses into tissues?

    <p>Deoxyhemoglobin</p> Signup and view all the answers

    What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

    <p>Sideroblastic anemia</p> Signup and view all the answers

    Which of the following is a known cause of methemoglobinemia?

    <p>Benzocaine</p> Signup and view all the answers

    What enzyme defect is associated with oxidative hemolysis?

    <p>Glucose 6 phosphate dehydrogenase deficiency</p> Signup and view all the answers

    Which leukemias involve myeloblasts?

    <p>Myelocytic leukemia</p> Signup and view all the answers

    What is the primary cause of death in leukemia?

    <p>Internal hemorrhage and overwhelming infections</p> Signup and view all the answers

    What represents hemoglobin bound to oxygen?

    <p>Oxyhemoglobin</p> Signup and view all the answers

    What effect do ethanol and glucocorticoids have on phagocytosis?

    <p>Impairment</p> Signup and view all the answers

    In which type of anemia does the alteration in hemoglobin function occur?

    <p>Sickle-cell anemia</p> Signup and view all the answers

    Which of the following is a leukemogenic agent?

    <p>Benzene</p> Signup and view all the answers

    Which type of anemia results from improper cell division due to the deficiency of folate and/or vitamin B12?

    <p>Megaloblastic anemia</p> Signup and view all the answers

    What represents hemoglobin bound to oxygen?

    <p>Oxyhemoglobin</p> Signup and view all the answers

    What leads to methemoglobinemia?

    <p>Failure of control mechanisms for reducing heme iron back to the ferrous state</p> Signup and view all the answers

    What type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

    <p>Sideroblastic anemia</p> Signup and view all the answers

    What effect do ethanol and zinc intoxication have on sideroblastic anemia?

    <p>Lead to defects in the synthesis of the porphyrin ring of the heme</p> Signup and view all the answers

    What effect does caffeine have on iron deficiency anemia?

    <p>Forms microcytic anemia with a decrease in the MCV</p> Signup and view all the answers

    What represents hemoglobin after oxygen diffuses into tissues?

    <p>Deoxyhemoglobin</p> Signup and view all the answers

    Which xenobiotic is capable of inducing oxidative injury to erythrocytes?

    <p>Naphthalene</p> Signup and view all the answers

    What is the primary cause of death in leukemia?

    <p>Internal hemorrhage and overwhelming infections</p> Signup and view all the answers

    Which leukemogenic agent is the only aromatic hydrocarbon known to cause leukemia?

    <p>Benzene</p> Signup and view all the answers

    Which cytokines hormonally stimulate leukopoiesis?

    <p>Interleukins and colony-stimulating factors</p> Signup and view all the answers

    What represents the process where all leukocytes originate from?

    <p>Hemocytoblasts</p> Signup and view all the answers

    What effect do ethanol and glucocorticoids have on phagocytosis?

    <p>Impairment</p> Signup and view all the answers

    Which type of anemia is characterized by defects in the synthesis of the porphyrin ring of the heme with its characteristic accumulation of iron in bone marrow erythroblasts?

    <p>Sideroblastic anemia</p> Signup and view all the answers

    What leads to methemoglobinemia?

    <p>Benzocaine</p> Signup and view all the answers

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