10 Questions
What is the main function of the hinge region of a B cell receptor (BCR)?
Regulate signaling events
How does the hinge region contribute to the diversity of BCR structures?
By varying in sequence
Which feature of the hinge region allows the BCR to recognize a wide range of antigens?
Variability in amino acid sequence
What role do disulfide bonds in the hinge region primarily serve?
Contributing to stability of the BCR structure
How does the hinge region of a BCR influence signaling events?
By transmitting signals from antigen-binding sites to intracellular domains
Which molecules can the hinge region of a BCR interact with?
Complement proteins
What structural characteristic allows the hinge region to be flexible?
Sequence variability
Why is the flexibility of the hinge region important for the BCR?
To allow recognition of diverse antigens
How would altering the sequence of the hinge region impact BCR function?
Impair the ability to recognize various antigens
Which structural element connects the antigen-binding Fab regions to the transmembrane region of a BCR?
Hinge region
Test your knowledge on the hinge region of a B cell receptor (BCR). Learn about the structure of heavy and light chains in an antibody and their roles in antigen binding. Understand the importance of the flexible hinge region in connecting the antigen-binding Fab regions to the transmembrane region of the receptor.
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