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Questions and Answers
Where are B-1 cells primarily found?
Where are B-1 cells primarily found?
- In lymph node germinal centers
- In peripheral blood lymphocytes
- In adults' bone marrow
- In the fetus and neonate (correct)
What is the main characteristic of antibodies secreted by B-1 cells?
What is the main characteristic of antibodies secreted by B-1 cells?
- High affinity and can bind to a specific antigen
- Low affinity and can bind to many different antigens (correct)
- High affinity and can bind to many different antigens
- Low affinity and can bind to a specific antigen
Which chromosomes contain the light chain loci for antibody construction?
Which chromosomes contain the light chain loci for antibody construction?
- Chromosome 22
- Chromosome 14
- Chromosomes 2 and 22 (correct)
- Chromosome 2
What is the process that B cells use to further recombine the antibody heavy chain genes?
What is the process that B cells use to further recombine the antibody heavy chain genes?
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Which cells secrete cytokines that program the activated B cell to undergo class switching?
Which cells secrete cytokines that program the activated B cell to undergo class switching?
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What promotes the differentiation into plasma cells that secrete IgM and promotes class switching to IgG2, IgG4, IgA, and IgE?
What promotes the differentiation into plasma cells that secrete IgM and promotes class switching to IgG2, IgG4, IgA, and IgE?
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What is responsible for the production of isoantibody to the ABO substance?
What is responsible for the production of isoantibody to the ABO substance?
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