10 Questions
What is the primary mechanism by which antigens are captured and presented to B cells in lymphoid tissue?
Antigen-presenting cells, such as dendritic cells, process and present antigens to B cells
Which of the following signals is required for B cell activation, but not for thymus-independent antigens?
Signal from the helper T cell through CD40L and cytokines
What is the process by which antibodies are modified to have higher affinity for antigens?
Somatic hypermutation and affinity maturation
Which of the following is NOT a mechanism by which antibodies protect the host from infection?
Phagocytosis
What is the primary function of the germinal center in the context of B cell activation?
B cell proliferation and differentiation
Which of the following cytokines is NOT involved in B cell activation and differentiation?
IL-12
What is the primary mechanism by which helper T cells provide a second signal for B cell activation?
Cytokine signaling through CD40L
Which of the following is a characteristic of natural antibodies?
They are produced by plasma cells in the absence of antigen stimulation
What is the primary function of plasma cells in the context of humoral immunity?
Antibody production and secretion
Which of the following is a requirement for B cell activation and differentiation?
Antigen binding to the B cell antigen receptor
Learn about the CD40-CD40L interaction, its role in immune response, and how it helps in B cell activation. Understand how TLR recognizes antigen-associated ligands and how helper T cells stimulate B cell proliferation and differentiation. Test your knowledge of the immune system!
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