Atherosclerotic Cardiovascular Disease Quiz
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Questions and Answers

What is considered a leading cause of morbidity and mortality in the world?

  • Myocardial infarction
  • Stroke
  • Atherosclerotic cardiovascular disease (correct)
  • Atherogenesis

At what age does the development of lipid-rich fibroinflammatory plaque in the arterial intima usually begin?

  • Early 20s (correct)
  • Late 50s
  • Late 40s
  • Early 30s

Which of the following is NOT listed as a classical modifiable vascular risk factor for atherosclerosis?

  • Genetics (correct)
  • Smoking
  • Obesity
  • Dyslipidemia

What is considered an acute event in atherosclerosis determined by plaque rupture or erosion?

<p>Plaque rupture (D)</p> Signup and view all the answers

Which of the following is NOT a factor influencing atherogenesis based on the provided text?

<p>Exercise (B)</p> Signup and view all the answers

What is one of the theories of atherogenesis according to the text?

<p><strong>Normal arterial physiology</strong> (A)</p> Signup and view all the answers

Which ethnic group is mentioned in the context as having a susceptibility to atherosclerosis?

<p><strong>South Asians</strong> (C)</p> Signup and view all the answers

What are the main categories listed under genetics contributing to atherosusceptibility?

<p><strong>Monogenic and Polygenic</strong> (A)</p> Signup and view all the answers

Which condition is NOT listed under inflammation as having an influence on atherosclerosis?

<p><strong>Hypertension</strong> (D)</p> Signup and view all the answers

What is the main function of tight junctions in endothelial cells?

<p>Maintain a non-thrombotic luminal surface (A)</p> Signup and view all the answers

What is the role of smooth muscle cells (SMCs) in arteries?

<p>Modulate artery diameter to meet metabolic needs (A)</p> Signup and view all the answers

What is the main function of the extracellular matrix (ECM) in arteries?

<p>Provide structural integrity against blood pressure (A)</p> Signup and view all the answers

How do endothelial cells respond to high shear stress (flow)?

<p>Align with the direction of flow and elaborate mediators (A)</p> Signup and view all the answers

What is the significance of FRS (Framingham Risk Score) mentioned in the text?

<p>Predicts 90% of coronary disease incidents globally (B)</p> Signup and view all the answers

What does the MESA study mentioned in the text involve?

<p>Studying asymptomatic patients for cultural differences in CAD risk (B)</p> Signup and view all the answers

What is the role of SMCs when they are in a quiescent state?

<p>Maintain relaxed and non-migratory state (D)</p> Signup and view all the answers

Why is the ECM important for artery physiology?

<p>Provides structural integrity against blood pressure (A)</p> Signup and view all the answers

How do endothelial cells respond to high shear stress?

<p>They align with the direction of flow and elaborate mediators. (A)</p> Signup and view all the answers

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