Atherosclerotic Cardiovascular Disease Quiz
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Questions and Answers

What is considered a leading cause of morbidity and mortality in the world?

  • Myocardial infarction
  • Stroke
  • Atherosclerotic cardiovascular disease (correct)
  • Atherogenesis

    • At what age does the development of lipid-rich fibroinflammatory plaque in the arterial intima usually begin?

  • Early 20s (correct)
  • Late 50s
  • Late 40s
  • Early 30s

    • Which of the following is NOT listed as a classical modifiable vascular risk factor for atherosclerosis?

  • Genetics (correct)
  • Smoking
  • Obesity
  • Dyslipidemia

    • What is considered an acute event in atherosclerosis determined by plaque rupture or erosion?

    <p>Plaque rupture</p> Signup and view all the answers

    Which of the following is NOT a factor influencing atherogenesis based on the provided text?

    <p>Exercise</p> Signup and view all the answers

    What is one of the theories of atherogenesis according to the text?

    <p><strong>Normal arterial physiology</strong></p> Signup and view all the answers

    Which ethnic group is mentioned in the context as having a susceptibility to atherosclerosis?

    <p><strong>South Asians</strong></p> Signup and view all the answers

    What are the main categories listed under genetics contributing to atherosusceptibility?

    <p><strong>Monogenic and Polygenic</strong></p> Signup and view all the answers

    Which condition is NOT listed under inflammation as having an influence on atherosclerosis?

    <p><strong>Hypertension</strong></p> Signup and view all the answers

    What is the main function of tight junctions in endothelial cells?

    <p>Maintain a non-thrombotic luminal surface</p> Signup and view all the answers

    What is the role of smooth muscle cells (SMCs) in arteries?

    <p>Modulate artery diameter to meet metabolic needs</p> Signup and view all the answers

    What is the main function of the extracellular matrix (ECM) in arteries?

    <p>Provide structural integrity against blood pressure</p> Signup and view all the answers

    How do endothelial cells respond to high shear stress (flow)?

    <p>Align with the direction of flow and elaborate mediators</p> Signup and view all the answers

    What is the significance of FRS (Framingham Risk Score) mentioned in the text?

    <p>Predicts 90% of coronary disease incidents globally</p> Signup and view all the answers

    What does the MESA study mentioned in the text involve?

    <p>Studying asymptomatic patients for cultural differences in CAD risk</p> Signup and view all the answers

    What is the role of SMCs when they are in a quiescent state?

    <p>Maintain relaxed and non-migratory state</p> Signup and view all the answers

    Why is the ECM important for artery physiology?

    <p>Provides structural integrity against blood pressure</p> Signup and view all the answers

    How do endothelial cells respond to high shear stress?

    <p>They align with the direction of flow and elaborate mediators.</p> Signup and view all the answers

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