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Questions and Answers

matured rbc are nucleated

True

matured rbc has a biconvex shape

False

what is the diameter of rbc

8.5 micrometer

what is the edge thickness

<p>2.5</p> Signup and view all the answers

what is the thickness

<p>1.5 micrometer</p> Signup and view all the answers

There are about how much million /mm3 of blood with variation between the two sexes?

<p>5</p> Signup and view all the answers

male is about what

<p>4.6 to 6</p> Signup and view all the answers

female is about

<p>4.3 to 4.5</p> Signup and view all the answers

the variation in rbc is due to what

<p>gonadal hormone testosterone in male which is an rbc differentiation inducer , greater mass musculature in male requires more oxygen supply</p> Signup and view all the answers

tell me about the shape of rbc

<p>it creates maximum surface area for small volume of the cell and large diffusion surface for passage of gasses</p> Signup and view all the answers

tell me more about the shape of the rbc

<p>it allows fir squeezing of rbc when passing through narrow vessels wirhout damage to the integrity if the cell</p> Signup and view all the answers

is present on the membrane helping to utilize glucoce,O2 and ATP

<p>Glucose-6phosphate dehydrogenase</p> Signup and view all the answers

what is the life span for rbc?

<p>120 days</p> Signup and view all the answers

the count is higher in new borns than in adults

<p>True</p> Signup and view all the answers

what is the count in new borns

<p>6 m</p> Signup and view all the answers

its production is stimulated by what

<p>hypoxia</p> Signup and view all the answers

release if erythropoetin as a redult of hypoxia is how nany percentage in kidney

<p>85%</p> Signup and view all the answers

from liver is how many %

<p>15%</p> Signup and view all the answers

erythropoetin is a what

<p>glycoprotein</p> Signup and view all the answers

Contains 165 aa residues & 4oligosaccharide chains

<p>True</p> Signup and view all the answers

it is a differentiation inducer

<p>True</p> Signup and view all the answers

half life is what in erythropoetin

<p>5hours</p> Signup and view all the answers

apart from hypoxia , what other thing is the epo stimulated by

<p>colbat and androgens</p> Signup and view all the answers

principal site of inactivaton of epo

<p>liver</p> Signup and view all the answers

whats affects epo production

<p>chronic renal disease</p> Signup and view all the answers

The gene is cloned and recombinant EPO is available for clinical use

<p>True</p> Signup and view all the answers

rbc is existing in an isotonic environment

<p>True</p> Signup and view all the answers

changed in stability afftects the stability and what of rbc?

<p>volume</p> Signup and view all the answers

at what salinity is rbc isotonic with plasma

<p>0.9</p> Signup and view all the answers

when does lysis begin

<p>0.5</p> Signup and view all the answers

0.4 to 0.42 saline lysis is what

<p>50%</p> Signup and view all the answers

when is saline lysis 100%

<p>0.35</p> Signup and view all the answers

buffy coat , what is that

<p>white cell that settle at the top of a testube after centrifuge</p> Signup and view all the answers

what is hematocrit

<p>fraction occupied by the rbc</p> Signup and view all the answers

what is the hemato crit in male and female and also averagely

<p>47% , 42%, 45</p> Signup and view all the answers

what is erythrocyte sedimentation rate

<p>rate of settlement if rbc without being centrifuged</p> Signup and view all the answers

what does erythrocyte sefimentation rate depend on

<p>shape of the cell and concentration of plasna protein and infection</p> Signup and view all the answers

what is roulex formation

<p>the stacking of rbc on each other</p> Signup and view all the answers

uses if erythrocyte sedimentstion rate rate

<p>monitoring recovering from disease or efficiency of treatment</p> Signup and view all the answers

it varies with what

<p>age and sex</p> Signup and view all the answers

it varies with what

<p>age and sex</p> Signup and view all the answers

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