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Questions and Answers
What is the primary function of albumins in blood plasma?
What is the primary function of albumins in blood plasma?
- Serving as a building block of the fibrin mesh that provides the foundation of clots
- Facilitating the transit of fatty acids and steroid hormones between tissues (correct)
- Aiding the uptake and distribution of iron
- Functioning as inhibitors of proteolytic enzymes
Which plasma protein helps confine the formation of clots to the vicinity of a wound?
Which plasma protein helps confine the formation of clots to the vicinity of a wound?
- Fibrinogen
- α1 -antiproteinase
- Transferrin
- Antithrombin (correct)
What health consequence can result from a deficiency in the production of circulating α1 -antiproteinase?
What health consequence can result from a deficiency in the production of circulating α1 -antiproteinase?
- Hepatolenticular degeneration
- Emphysema (correct)
- Excessive bruising and bleeding
- Autoimmune disorders
What is the primary role of albumins in blood plasma?
What is the primary role of albumins in blood plasma?
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What is the consequence of a deficiency in plasma ceruloplasmin?
What is the consequence of a deficiency in plasma ceruloplasmin?
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What is the role of antithrombin in blood plasma?
What is the role of antithrombin in blood plasma?
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Study Notes
Functions of Plasma Proteins
- Albumins maintain osmotic pressure in blood plasma, regulating fluid balance between blood and tissues.
- They transport various substances, including hormones, vitamins, and drugs, aiding in nutrient distribution.
Coagulation and Wound Healing
- Fibrinogen, a plasma protein, confines clot formation to the area of a wound, preventing excessive bleeding and ensuring localized healing.
Health Implications of Protein Deficiency
- A deficiency in circulating α1-antiproteinase can lead to unchecked enzyme activity, resulting in tissue damage, lung disorders (e.g., emphysema), and accelerated aging of tissues.
Role of Plasma Ceruloplasmin
- Insufficient plasma ceruloplasmin levels can cause Wilson's disease, leading to copper accumulation in tissues, liver damage, and neurological disorders.
Function of Antithrombin
- Antithrombin functions as a natural anticoagulant that inhibits thrombin and other clotting factors, regulating blood coagulation and preventing excessive clotting.
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