Topic 7 - Chromosomal Mutations 8a4a3fddc70840eca9255d0e67accf5b.pdf

🦿 Topic 7 - Chromosomal Mutations Define Satellite DNA Repetitive DNA with an unclear function 2 Major Classes - Alpha Repeats (171 bp) + Beta Repeats (68 bp) Tandem Repeats...

🦿 Topic 7 - Chromosomal Mutations Define Satellite DNA Repetitive DNA with an unclear function 2 Major Classes - Alpha Repeats (171 bp) + Beta Repeats (68 bp) Tandem Repeats tenderly repetitive sequences Mini satellites - short tandem repeats (STRs) Micro satellites - near telomeres Macro Satellites - near centromeres and telomeres, megabases long Telomeric Repeats Clusters of repeated 6bp TTAGGG in humans up to several kb long protect integrity of chromosomes Topic 7 - Chromosomal Mutations 1  Allow the replication of the extreme ends of chromosomes Defects in telomere maintenance involved in cancer and aging Dispersed Repeats interspersed repetitive DNA SINEs (