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Summary

This is a list of the top 200 drugs, along with their classifications, mechanisms of action, uses, and side effects.

Full Transcript

Top 200 drugs 1 Amoxicillin & Clavulanate Potassium Generic: Amoxicillin & Clavulanate Potassium Brand: Augmentin (XR) Class: Antibiotic, Penicillin Mechanism of action: Beta lactamase inhibitor/Cell wall synthesis inhibitor Control Schedule: VI Dosa...

Top 200 drugs 1 Amoxicillin & Clavulanate Potassium Generic: Amoxicillin & Clavulanate Potassium Brand: Augmentin (XR) Class: Antibiotic, Penicillin Mechanism of action: Beta lactamase inhibitor/Cell wall synthesis inhibitor Control Schedule: VI Dosage form: oral (tablets), oral powder for reconstitution Uses: Acute otitis, Infections in lower respiratory and urinary tract Side effects: rash, nausea, vomiting, cough, diarrhea 2 Amoxicillin Trihydrate Generic: Amoxicillin Trihydrate Brand: Amoxil, Moxatag, Trimox Class: Antibiotic, Penicillin Mechanism of action: Cell wall synthesis inhibition Control Schedule: VI Dosage form: oral, oral powder for reconstitution7 USES: Ear, nose, and throat infection SIDE EFFECTS: Diarrhea, headache, vomiting, dysgeusia 3 Azithromycin Dihydrate Generic: Azithromycin Dihydrate Brand: Zithromax & Zmax Class: Antibiotic, Macrolide Dosage form: tablets, oral powder for reconstitution, powder for injection/solution Control Schedule: VI Mechanism of action: Inhibition of protein synthesis Uses: infections that are caused by bacteria (treat ear infections (e.g., otitis media), throat infections, respiratory infections (e.g., pneumonia), and skin infections. Side effects: Abdominal pain, Nausea, Vomiting, diarrhea, injection site reaction 4 Cefdinir Generic: Cefdinir Brand: Omnicef Class: Antibiotic, Cephalosporin (Third Generation) Mechanism of action: Bacterial cell wall synthesis inhibition Control Schedule: VI Dosage form: oral powder for reconstitution, capsule, powder for injection/solution Uses: Acute otitis, Bronchitis, Community acquired pneumonia, bacterial infections Side effects: Diarrhea, Nausea, Candida vaginitis 5 Cefuroxime Axetil Generic: Cefuroxime Axetil Brand: Ceftin Class: Antibiotic, Cephalosporin (Second Generation) Mechanism of action: Inhibition of bacterial cell wall Control Schedule: VI Dosage form: suspension, tablets, powder for injection Uses: Bacterial infections Side effects: Anemia, Diarrhea, Nausea and vomiting and Vaginitis 6 Cephalexin Monohydrate Brand: Cephalexin Monohydrate Generic: Keflex Class: Antibiotic, Cephalosporin (First Generation) Mechanism of action: Inhibition of bacterial cell wall Control Schedule: VI Dosage form: tablet, oral powder for reconstitution, capsule, USES: Urinary tract infectious disease, bacterial infections SIDE EFFECTS: Nausea, elevated hepatic enzymes, Headache, rash 7 Ciprofloxacin Hydrochloride Generic: Ciprofloxacin Hydrochloride Brand: Cipro (XR) Class: Antibiotic, Fluoroquinolone Dosage form: suspension, tablet, Ophthalmic, otic, solution for injection Control Schedule: VI Mechanism of action: Inhibition of DNA Gyrase USES: Bacterial infections (large variety) SIDE EFFECTS: Rash, Diarrhea, Nausea, Dizziness, dysgeusia, eye discharge, corneal deposit, pharyngitis, irritability 8 Clindamycin Hydrochloride (oral) Generic: Clindamycin Hydrochloride (oral) Brand: Cleocin Class: Antibiotic, Lincosamide Dosage form: capsule, oral powder for reconstitution, topical pledget, solution for injection Control Schedule: VI Mechanism of action: Inhibition of protein synthesis USES: Bacterial infectious disease, Infection of skin AND/OR subcutaneous tissue (Severe), acne SIDE EFFECTS: Pruritus, Abdominal pain, Diarrhea, Nausea, vaginitis, dry skin 9 Doxycycline Hyclate Generic: Doxycycline Hyclate Brand: Vibramycin Class: Antibiotic, Tetracycline Derivative Dosage form: capsule, tablet, powder oral for reconstitution Control Schedule: VI Mechanism of action: Bacterial protein synthesis inhibition USES: Bacterial infections, malaria prevention, skin infections SIDE EFFECTS: Influenza, Rash, Diarrhea, Loss of appetite, Nausea, Vomiting, dyspepsia 10 Fluconazole Generic: Fluconazole Brand: Diflucan Class: Antifungal Agent, triazole Dosage form: capsule, tablet, powder for oral reconstitution Control Schedule: VI Mechanism of action: Inhibition of ergosterol synthesis USES: Bone marrow transplant - Candidiasis, fungal infections (various body systems), pyelonephritis, thrush SIDE EFFECTS: Nausea, Vomiting, Headache 11 Levofloxacin Generic: Levofloxacin Brand: Levaquin Class: Antibiotic, Fluoroquinolone; Respiratory Fluoroquinolone Dosage form: tablet, Ophthalmic drops, oral solution, solution for injection Mechanism of action: Inhibition of DNA gyrase Control Schedule: VI USES: respiratory and urinary tract infections, bacterial infections (various body systems) SIDE EFFECTS: Diarrhea, Nausea , Headache, Insomnia, dysgeusia 12 Metronidazole Generic: Metronidazole Brand: Flagyl Class: Amebicide; Antibiotic, Miscellaneous; Antiprotozoal, Nitroimidazole Dosage form: tablet, capsule, cream, emulsion, ointment, gel, oral suspension, solution for injection Mechanism of action: Inhibition of DNA synthesis Control Schedule: VI USES: Abscess, Anaerobic,, It fights bacteria in your body, used to treat bacterial infections of the vagina, stomach, skin, joints, and respiratory tract. SIDE EFFECTS: Abdominal discomfort, Abnormal taste in mouth, diarrhea, headache, vaginitis, nausea 13 Minocycline Hydrochloride Generic: Minocycline Hydrochloride Brand: Minocin Class: tetracycline antibiotic Dosage form: capsule, tablet, foam Control Schedule: VI Mechanism of action: Bacterial protein synthesis inhibition USES: treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, SIDE EFFECTS: Tooth discolored, Dizziness, Headache, Fatigue, burning/stinging, flushing 14 Mupirocin (topical) Generic: Mupirocin (topical) Brand: Bactroban Class: Antibacterial, Dermatological Agent Dosage form: ointment, cream Mechanism of action: Inhibition of bacterial protein synthesis Control Schedule: VI USES: treatment of impetigo, skin and soft tissue infection SIDE EFFECTS: Application site pain, Sensation of burning of skin, Stinging of skin, rash, headache 15 Nitrofurantoin Generic: Nitrofurantoin Brand: Macrodantin & Macrobid Class: Antibiotic, Miscellaneous Dosage form: Capsule, oral suspension Mechanism of action: Inactivation of bacterial ribosomal proteins Control schedule: VI USES: Urinary tract infectious disease, Urinary tract infectious disease; Prophylaxis of UTI SIDE EFFECTS: Loss of appetite, Nausea, Vomiting, dizziness 16 Oseltamivir Phosphate Generic: Oseltamivir Phosphate Brand: Tamiflu Class: Antiviral, neuraminidase inhibitor Dosage form: capsule, oral suspension USES: blocks the actions of influenza virus types A and B Control schedule: VI Mechanism of action: Inhibition of neuraminidase enzyme SIDE EFFECTS: Abdominal pain , Nausea, Vomiting, headache 17 Penicillin V Generic Penicillin V Brand: Pen VK Class: Naturally derived antibiotic, Penicillin Dosage form: capsule, tablet, powder for oral reconstitution Control Schedule: VI Mechanism of action: Inhibition of bacterial cell wall synthesis USES: Cellulitis, otitis media, pharyngitis SIDE EFFECTS: Skin irritation, diarrhea, rash 18 Pivmecillinam Generic: Pivmecillinam Brand: Pivya Class: Amidinopenicillin antibiotic Dosage form: Tablet Control Schedule: VI Mechanism of action: Bacterial cell wall synthesis inhibition USES: Uncomplicated urinary tract infection SIDE EFFECTS: Candidiasis, diarrhea, headache, nausea 19 Sulfamethoxazole & Trimethoprim Generic: Sulfamethoxazole & Trimethoprim Brand: Bactrim, Septra Class: Antibiotic,Sulfonamide Derivative Dosage form: oral suspension, tablet, solution for injection Mechanism of action: Nucleic acid and protein inhibition Control schedule: VI USES: Acute infective exacerbation of chronic obstructive pulmonary disease, bacterial infections, UTI, opportunistic infections, otitis media SIDE EFFECTS: Rash, Urticaria, Loss of appetite, Nausea, Vomiting. Crystalluria, potassium excess 20 Vancomycin Generic: Vancomycin Brand: Vancocin Class: Glycopeptide Dosage form: capsule, powder for reconstitution, injection, powder for injection Control Schedule: VI Mechanism of action: Inhibition of cell wall synthesis USES: Bone marrow transplant - Various skin infections, osteomyelitis, pneumonia, sepsis SIDE EFFECTS: Abdominal pain, hypokalemia, nausea, neutropenia, skin irritation/peeling in extreme circumstances 21 Acyclovir Generic: Acyclovir Brand: Zovirax Class: Antiviral agent, acyclic guanosine analog Dosage form: oral, topical Mechanism of action: Inhibits viral DNA synthesis Control schedule: VI USES: Genital herpes, Recurrent herpes, chickenpox, shingles, viral blood infection SIDE EFFECTS: Malaise, nausea, headache, skin irritation 22 Emtricitabine and Tenofovir Disoproxil Fumarate Generic: Emtricitabine and Tenofovir Disoproxil Fumarate Brand: Truvada Class: Nucleoside reverse transcriptase inhibitor and acyclic nucleotide analog (For HIV) Dosage form: Tablet Control Schedule: VI Mechanism of action: Inhibition of viral DNA incorporation and inhibition of viral reverse transcriptase USES: HIV, HIV prophylaxis SIDE EFFECTS: High cholesterol, abdominal pain, abnormal dreams, 23 diarrhea, dizziness, headache, fatigue Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Generic: Elvitegravir, Cobicistat, Emtricitabine, and Tenofovir Alafenamide Brand: Genvoya Class: Multimodal (4 drugs) for treatment of HIV Dosage form: Tablet Control Schedule: VI Mechanism of action: Integrase inhibitor, kinetic booster (3A enzyme inhibitor) of other meds, inhibitor of viral reverse transcriptase, competitive inhibitor if RNA&DNA reverse transcriptase USES: HIV SIDE EFFECTS: High cholesterol, abdominal pain, abnormal dreams, diarrhea, dizziness, headache, fatigue 24 Nirmatrelvir and Ritonavir Generic: Nirmatrelvir and Ritonavir Brand: Paxlovid Class: Oral antiviral Dosage form: Tablet Control Schedule: VI Mechanism of action: Protease inhibitor, CYP3A inhibitor USES: COVID-19 SIDE EFFECTS: Diarrhea, dysgeusia 25 Valacyclovir Hydrochloride Generic: Valacyclovir Hydrochloride Brand: Valtrex Class: Antiviral Agent; Dosage form: Tablet Mechanism of action: Inhibition of viral DNA synthesis Control schedule: VI USES: Herpes, opportunistic infections (from HIV) , treat infections caused by certain types of viruses, shingles, genital herpes SIDE EFFECTS: Rash, abdominal pain , nausea, headache 26 Acetaminophen and Codeine Phosphate Generic: Acetaminophen and Codeine Phosphate Brand: Tylenol (& Codeine #3, #4) Class: Analgesic Mechanism of Action: Combination product with an opioid. Reduces pain using the mu opioid receptors and COX-2 receptors Control Schedule: III Dosage Form: Solution, Tablet, Elixir Uses: mild to moderate pain Side Effects: Constipation, Nausea 27 Allopurinol Generic: Allopurinol Brand: Zyloprim Class: Xanthine Oxidase Inhibitor, Analgesic Mechanism of Action: Reduces production of uric acid Control Schedule: VI Dosage Form: Tablet, Powder for injection Uses: Treatment for gout, prevention of hyperuricemia (increased uric acid) Side Effects: Diarrhea, rash, liver failure, vomiting 28 Buprenorphine and Naloxone Generic: Buprenorphine and naloxone Brand: Suboxone Class: Combination of opioid agonist-antagonist Mechanism of Action: Buprenorphine – partial agonist, naloxone – antagonist (both at the mu opioid receptors) Control Schedule: III Dosage Form: Sublingual film, sublingual tablet Uses: Treatment of opioid dependence Side Effects: abdominal pain, constipation, headache, anxiety, depression 29 Butalbital, Acetaminophen, and Caffeine Generic: Butalbital, Acetaminophen, and Caffeine Brand: Fioricet Class: Barbiturate Mechanism of Action: CNS depression, analgesia, and CNS stimulant for blood flow (work in combination) Control Schedule: III Dosage Form: Capsule, tablet, solution Uses: tension headache, acute treatment of migraine Side Effects: Abdominal pain, nausea, dizziness, sedation, dyspnea (difficulty breathing) 30 Celecoxib Generic: Celecoxib Brand: Celebrex Class: NSAID Mechanism of Action: Inhibits COX-1 and COX-2 enzymes Control Schedule: VI Dosage Form: Capsule Uses: Moderate to severe pain, osteoarthritis, rheumatoid arthritis Side Effects: diarrhea, headache, hypertension, dyspepsia, abdominal pain 31 Diclofenac Sodium Generic: Diclofenac sodium Brand: Flector, Voltaren (XR), Zipsor Class: NSAID Mechanism of Action: Inhibits COX 1 and COX 2 enzymes Control Schedule: VI Dosage Form: Tablet, Capsule, Patch, Oral powder, topical, opthalmic Uses: Mild to moderate pain, osteoarthritis, rheumatoid arthritis Side Effects: GI bleeding/perforation, contact dermatitis (opthalmic), edema, application site reaction (topical) 32 Fentanyl Hydrochloride Generic: Fentanyl Hydrochloride Brand: Duragesic Class: Opioid Mechanism of Action: Opioid receptor agonist Control Schedule: II Dosage Form: Patch, sublingual spray, sublingual tablet, nasal spray, injection Uses: Treatment of severe pain, breakthrough pain Side Effects: constipation, nausea, vomiting 33 Hydrocodone Bitartrate and Acetaminophen Generic: Hydrocodone Bitartrate and Acetaminophen Brand: Lortab, Lorcet, Norco, Vicodin Class: Analgesic + Opioid agonist Mechanism of Action: Acetaminophen inhibits COX1and 2, hydrocodone is an opioid agonist Control Schedule: II Dosage Form: Capsule, tablet, oral solution Uses: treatment of severe pain Side Effects: constipation, liver failure, N/V 34 Hydromorphone HCL Generic: Hydromorphone hydrochloride Brand: Dilaudid Class: Opioid Mechanism of Action: Opioid agonist at receptors Control Schedule: II Dosage Form: Capsule, tablet, injection Uses: Treatment of severe pain Side Effects: constipation, CNS depression (drowsiness, fatigue), nausea, vomiting 35 Ibuprofen Generic: Ibuprofen Brand: Advil, Motrin Class: NSAID Mechanism of Action: Inhibits COX1 and COX2 Control Schedule: VI Dosage Form: Tablet, chewable tablet, capsule, suspension, Uses: fever, pain, rheumatoid/osteo arthritis, headache Side Effects: abdominal pain, constipation, anemia, diarrhea, dyspepsia 36 Meloxicam Generic: Meloxicam Brand: Mobic Class: NSAID Mechanism of Action: Inhibits COX1 and COX2 Control Schedule: VI Dosage Form: capsule, tablet, suspension, Uses: Moderate to severe pain, rheumatoid/osteo arthritis Side Effects: nausea, headache, laryngitis, dyspepsia, edema, abdominal pain 37 Methadone Hydrochloride Generic: Methadone HCl Brand: Methadone, Dolophine Class: Opioid Mechanism of Action: agonist at the opioid receptors Control Schedule: II Dosage Form: Solution, suspension, tablet, injection Uses: Treatment of opioid dependence, pain Side Effects: constipation, abdominal pain, bradycardia 38 Morphine Sulfate Generic: Morphine Sulfate Brand: MS Contin, Kadian, Duramorph Class: Opioid Mechanism of Action: Agonist at opioid receptor Control Schedule: II Dosage Form: Capsule, tablet, solution, injection Uses: Severe pain, persistent pain Side Effects: confusion, drowsiness, dyspnea, fever 39 Naproxen Generic: Naproxen Brand: Aleve, Naprelan, Naprosyn and EC-Naprosyn Class: NSAID Mechanism of Action: Inhibits COX1 and COX2 Control Schedule: VI Dosage Form: Suspension, tablet, capsule Uses: Rheumatoid/osteo arthritis, mild-mod pain, musculoskeletal pain Side Effects: dyspepsia, elevated liver (hepatic) enzymes, headache, constipation, GI bleeding 40 Oxycodone Hydrochloride Generic: Oxycodone HCl Brand: Oxycontin, Roxicodone, Oxaydo Class: Opioid Mechanism of Action: Agonist at opioid receptor Control Schedule: II Dosage Form: Capsule, tablet, solution Uses: Severe pain Side Effects: constipation, drowsiness, nausea, vomiting 41 Oxycodone Hydrochloride and Acetaminophen Generic: Oxycodone HCl and Acetaminophen Brand: Percocet, Roxicet, Endocet Class: Opioid + analgesic Mechanism of Action: Agonist at opioid receptors, COX 1 and 2 inhibition Control Schedule: II Dosage Form: Capsule, tablet, solution Uses: moderate to severe pain Side Effects: constipation, dizziness, headache, nausea, vomiting 42 Sumatriptan Succinate Generic: Sumatriptan succinate Brand: Imitrex Class: selective serotonin receptor agonist (SSRI) Mechanism of Action: Stimulates presynaptic serotonin (5- HT1) receptors Control Schedule: VI Dosage Form: tablet, injection, nasal spray, patch Uses: treatment of migraine, cluster headaches Side Effects: vertigo, injection site reaction, dysgeusia (altered taste) 43 Tramadol Hydrochloride Generic: Tramadol HCl Brand: Ultram Class: Opioid Mechanism of Action: Agonist at opioid receptor Control Schedule: IV Dosage Form: Capsule, tablet, solution Uses: Severe pain, treatment for postherpetic neuralgia, restless leg syndrome Side Effects: agitation, anxiety, constipation, dizziness, drowsiness, headache 44 Clopidogrel Generic: Clopidogrel Brand: Plavix Class: Antiplatelet Mechanism of Action: selectively and irreversibly inhibits ADP- induced platelet aggregation Control Schedule: VI Dosage Form: Tablet Uses: thromboembolic (myocardial infarction, stroke, thrombosis) prophylaxis Side Effects: bleeding, hematoma, headache, dizziness, abdominal 45 pain Ezetimibe Generic: Ezetimibe Brand: Zetia Class: Antilipemic agent Mechanism of Action: inhibiting the absorption of cholesterol in the small intestine Control Schedule: VI Dosage Form: Tablet Uses: Hyperlipidemia Side Effects: arthralgia, back pain, elevated hepatic enzymes, abdominal pain, diarrhea 46 Fenofibrate Generic: Fenofibrate Brand: Antara, Tricor, Triglide, Trilipix Class: Antilipemic agent, fibric acid derivative Mechanism of Action: Activates peroxisome proliferator-activated receptor-alpha (PPAR-α), increasing lipi breakdown Control Schedule: VI Dosage Form: capsule, tablet Uses: hypertriglyceridemia, hyperlipidemia Side Effects: elevated hepatic enzymes, abdominal pain, diarrhea/constipation 47 Lovastatin Generic: Lovastatin Brand: Altoprev, Mevacor Class: Antilipemic agent, HMG-CoA reductase inhibitor Mechanism of Action: competes at the HMG-CoA reductase enzyme receptors to reduce LDL and cholesterol levels Control Schedule: VI Dosage Form: Tablet Uses: Hyperlipidemia Side Effects: infections, arthralgia, myalgia 48 Nitroglycerin Generic: Nitroglycerin (sublingual and injectable) Brand: Nitrostat, Nitroquick Class: Nitrates Mechanism of Action: stimulates the enzyme guanylate cyclase, which leads to an increase in cyclic guanosine monophosphate (cGMP) levels in the smooth muscle, causing vasodilation Control Schedule: VI Dosage Form: sublingual, injectable Uses: Angina pectoris, acute congestive heart failure, unstable angina, acute myocardial infarction, hypertensive emergency Side Effects: headache, hypotension, dizziness, nausea, syncope 49 Pravastatin Sodium Generic: Pravastatin sodium Brand: Pravachol Class: Antilipemic agent, HMG-CoA reductase inhibitor Mechanism of Action: competes at the HMG-CoA reductase enzyme receptors to reduce LDL and cholesterol levels Control Schedule: VI Dosage Form: Tablet Uses: hyperlipidemia Side Effects: chest pain, musculoskeletal pain, cough, diarrhea, dizziness, fatigue, rash, vomiting 50 Rivaroxaban Generic: Rivaroxaban Brand: Xarelto Class: selective factor Xa inhibitor anticoagulant Mechanism of Action: selectively blocks the active site of factor Xa Control Schedule: VI Dosage Form: tablet, suspension Uses: stroke prophylaxis, treatment and prophylaxis of venous thromboembolism, deep vein thrombosis and pulmonary embolism Side Effects: bleeding, cough, menorrhagia, vomiting 51 Rosuvastatin Calcium Generic: Rosuvastatin calcium Brand: Crestor Class: Antilipemic agent, HMG-CoA reductase inhibitor Mechanism of Action: competes at the HMG-CoA reductase enzyme receptors to reduce LDL and cholesterol levels Control Schedule: VI Dosage Form: tablet, capsule Uses: hyperlipidemia, reduction of cardiovascular mortality Side Effects: arthralgia, myalgia, constipation, headache, nausea 52 Simvastatin Generic: Simvastatin Brand: Zocor Class: Antilipemic agent, HMG-CoA reductase inhibitor Mechanism of Action: competes at the HMG-CoA reductase enzyme receptors to reduce LDL and cholesterol levels Control Schedule: VI Dosage Form: tablet, suspension Uses: hyperlipidemia Side Effects: abdominal pain, atrial fibrillation, constipation, headache, infection, gastritis 53 Spironolactone Generic: Spironolactone Brand: Aldactone Class: Potassium-sparing diuretic Mechanism of Action: inhibits the effects of aldosterone in the distal renal tubules, enhancing sodium, chloride, and water excretion. Lowers blood pressure Control Schedule: VI Dosage Form: suspension, tablet Uses: hypertension, heart failure, edema due to cirrhosis Side Effects: hyperkalemia (increase potassium), gout (increases uric acid), bradycardia, dehydration 54 Triamterene and HCTZ Generic: Triamterene and hydrochlorothiazide Brand: Dyazide, Maxzide, Maxzide-25 Class: diuretic (combination) Mechanism of Action: produces antihypertensive effects by increasing the excretion of sodium Control Schedule: VI Dosage Form: Capsule, tablet Uses: treatment of hypertension, peripheral edema Side Effects: gout, hyperglycemia (inc glucose), hyperkalemia (inc potassium), hyperuricemia (inc uric acid) ------ ALL RARE 55 Warfarin Sodium Generic: Warfarin sodium Brand: Coumadin, Jantoven Class: anticoagulant Mechanism of Action: inhibits the synthesis of Vitamin K dependent coagulation factors II, VII, IX, X and protein C and S Control Schedule: VI Dosage Form: tablet Uses: treatment and prophylaxis of deep vein thrombosis (DVT) and pulmonary embolism (PE) Side Effects: bleeding, ocular hemorrhage 56

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