Sepsis Part 1 PDF

Health Variations 4 NURS3015 Sepsis- Part 1 Systemic Inflammatory Response Syndrome (SIRS) SIRS is a systemic inflammatory response to a variety of insults infection ischemia Infarction injury Generalised inflammation in organs remote from the initial insult characterises...

Health Variations 4 NURS3015 Sepsis- Part 1 Systemic Inflammatory Response Syndrome (SIRS) SIRS is a systemic inflammatory response to a variety of insults infection ischemia Infarction injury Generalised inflammation in organs remote from the initial insult characterises SIRS SIRS criteria Tachycardia (heart rate >90 beats/min) Tachypnoea (respiratory rate >20 breaths/min) Fever or hypothermia (temperature >38 or 1,200/mm3, 7.7 mmol/L (not if diabetic) ABC of Sepsis (2010)  Sepsis Life-threatening organ dysfunction caused by a dysregulated host response to infection  Sepsis definition Davidson’s Principles of Internal Medicine (2019);Vincent et.al., BMJ  Risk factors of sepsis a genetic predisposition to sepsis a large microbiological load high virulence of the organism delay in source control (either surgical or antimicrobial) resistance of the organism to treatment patient factors (immune status, nutrition, frailty). Sepsis Causes Davidson’s Principles of Internal Medicine (2019) Sepsis Causes Clinical Excellence Commission References Daniels, R & Nutbeam,T. ABC of Sepsis. Chichester, West Sussex ; Hoboken, NJ: BMJ/ Wiley-Blackwell, 2010. Craft, Judy, Gordon, Christopher J., Author, Huether, Sue E, McCance, Kathryn L, Author, and Rote, Neal S. Understanding Pathophysiology. 3e, Australian and New Zealand ed. 2019. Linton, Adrianne Dill, Matteson, Mary Ann. Medical-surgical Nursing. 7th ed. 2020. Jameson, J. Larry, Fauci, Anthony S., Editor, Kasper, Dennis L., Loscalzo, Joseph, and Harrison, Tinsley Randolph. Harrison's Principles of Internal Medicine. 20th ed. 2018. Ralston, Stuart. Davidson's Principles and Practice of Medicine. 23rd ed. Elsevier Health Sciences, 2018.