Practical 2 b bleeding time_organized 2_organized.pdf

4.Normal value: 1-4 min. 5.Factors affecting: Bleeding time is prolonged in purpura which may be due to: a)Disorders in platelets; b)Disorders in wall of blood vessels (capillary fragility or vascular purpura) a)Disorders in platelets; 1.decrease in number (thrombocytopenic purpura) e.g. B.M. disord...

4.Normal value: 1-4 min. 5.Factors affecting: Bleeding time is prolonged in purpura which may be due to: a)Disorders in platelets; b)Disorders in wall of blood vessels (capillary fragility or vascular purpura) a)Disorders in platelets; 1.decrease in number (thrombocytopenic purpura) e.g. B.M. disorders due to decrease synthesis or increase destruction Purpura with bleeding under skin 2.decrease in function (thromboasthenic purpura) b)Disorders in wall of blood vessels (capillary fragility or vascular purpura) e.g. vit. C deficiency (scurvy) scurvy Purpura with bleeding under m.m. 6.Clinical significance: -bleeding time is prolonged in: Purpura Scurvy Prolonged use of aspirin