PHARMACOLOGY CAT II.pdf

NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ MINISTRY OF HEALTH KARAGWE INSTITUTE OF HEALTH AND ALLIED SCIENCE (KIHAS) BASIC TECHNICIAN CERTIFICATE IN PHARMACEUTICAL SCIENCES (NTA...

NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ MINISTRY OF HEALTH KARAGWE INSTITUTE OF HEALTH AND ALLIED SCIENCE (KIHAS) BASIC TECHNICIAN CERTIFICATE IN PHARMACEUTICAL SCIENCES (NTA LEVEL 4) CONTINOUS ASSSMENT TEST TWO MODULE CODE: PST 04211 MODULE NAME: BASIC PHARMACOLOGY TIME: 2 HOURS DATE: ____________________ (THEORY PAPER) GENERAL INSTRUCTIONS 1. Read all instruction in each sections carefully 2. This examination paper consists of five (5) sections A, B, C, D and E. 3. Write your registration number and examination number on each page of answer sheet used 4. Answer all questions from each section 5. Cell phones and other unauthorized materials are NOT allowed in the examination room FOR OFFICIAL USE ONLY SECTION TYPE OF QUESTION MARKS MARKS MARKER’S VERIFIER’S ALLOCATED SCORED INITIALS INITIALS A MULTIPLE CHOICE 10 B MULTIPLE TRUE/ FALSE 10 C MATCHING ITEMS 10 D SHORT ANSWER 40 E GUIDED ESSAY 30 TOTAL 100 1 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ SECTION A: MULTIPLE CHOICE QUESTIONS (10 MARKS) INSTRUCTIONS:  This section consists of ten (10) questions, each having five (5) options  Write the letter of the most correct answer in the box provided  One mark will be awarded for each correct answer 1. Answer item (i) – (x) by choosing the letter of the most correct answer and write it in the box provided using CAPITAL letter i. Which dosage of ALU is taken as direct observation therapy? A. All dose B. First dose C. Third dose D. Fourth dose E. Second dose ii. The common cause of iatrogenic hyponatremia in surgical patients is? A. Dextrose 10% B. Dextrose 50% C. Sodium chloride D. Sodium lactate compound E. Potassium chloride solution iii. The following drug May increase hypoglycemic effects of insulin;- A. Danazol B. Isoniazid C. Diltiazem D. Diazoxide E. Guanethidine iv. Which of the following Increase plasma levels of Efavirenz leading to increased risk of rash;- A. Phenytoin B. Tobramycin C. Griseofulvin D. Clarithromycin E. Carbamazepine v. High dose and prolonged use of paracetamol may lead to;- A. Asthma B. Diarrhea C. Ototoxicity D. Hypertension E. Liver damage 2 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ vi. Which anti-TB drug commonly causes cholestatic jaundice and hepatitis as adverse effects? A. Isoniazid B. Cycloserine C. Rifampicin D. Ethambutol E. Pyrazinamide vii. Metallic taste is common side effects of which drugs? A. Clonidine B. Amoxicillin C. Paracetamol D. Erythromycin E. Metronidazole viii. Pseudoephedrine is used in management of? A. Cough B. Asthma C. Hemorrhoids D. Keto-acidosis E. Nasal congestion ix. Quinine should be avoided to the patients with;- A. Psoriasis B. Angina pectoris C. Hepatic cirrhosis D. Ectopic pregnancy E. Visual and auditory problem x. Drug affecting associated with chromaturia is called? A. Ferrous sulphate B. Folic acid C. Dextran injection D. Vitamin B 12 E. Hydroxycobalamin 3 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ SECTION B: MULTIPLE TRUE AND FALSE QUESTIONS (10MARKS) INSTRUCTIONS;-  This section consists of four(4) questions with five options  Write the word TRUE for correct statement and word FALSE for wrong statement in the space provided  0.5 mark will be awarded for each correct answer 2. Drugs with anti-allergies properties;- A. Adrenaline ___________ B. Promethazine ______________ C. Hydrocortisone ______________ D. Cetirizine hydrochloride________________ E. Chlorpheniramine maleate ________________ 3. Regarding the classes of antianginal drugs;- A. Diuretics ____________ B. Organic nitrates _________ C. Sodium channel blocker _________ D. Calcium channel blocker _________ E. Beta-adrenoreceptor antagonist _________ 4. Regarding the adverse effects of cardiac glycosides;- A. Nausea ________ B. vomiting ___________ C. arrhythmias ________ D. Constipation __________ E. Bronchospasm ___________ 5. Corticosteroids antagonize hypertensive effects of: A. Alpha blockers______________ B. ACE inhibitors________________ C. Direct vasodilators______________ D. Calcium channel blockers____________ E. Adrenergic neuron blockers____________ 4 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ SECTION C: - MATCHING ITEMS QUESTIONS (10MARKS) INSTRUCTIONS:-  This section consists of ten (10) matching item questions with two parts each containing five questions  Match the items in column A with corresponding statements in column B by writing a letter of correct response in the space provided  Each correct response is awarded 1 mark. 6. A) Match the groups of drug from column A with their corresponding examples at column B. SN COLUMN A COLUMN B i. Blood boosters A. Methyldopa ii. Anti-epileptics B. Glyceryl nitrate iii. Anticoagulants C. Folic acid iv. Anti-angina drugs D. Mannitol v. Antihypertensive drugs E. Lidocaine F. Carbamazepine G. Prednisolone H. Tranexamic acid QUESTIONS I. II. III. IV. V. ANSWERS B) Match the solution for correcting electrolyte imbalance from column A with their corresponding indication at column B. SN COLUMN A COLUMN B i. Sodium lactate compound A. Hypokalemia (ringer lactate) ii. Sodium chloride (normal B. Maintains water balance to the patients with saline) starvation deficit iii. Dextrose 50% C. Hypoglycemia iv. Sodium chloride + dextrose D. Intravascular resuscitation and replacement of salt (dextrose saline) loss v. Potassium chloride solution E. Intraoperative F. Hyperkalemia G. Hyperglycemia H. Cause water and salt overload QUESTIONS I. II. III. IV. V. ANSWERS 5 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ SECTION D: SHORT ANSWER QUESTIONS (40MARKS) INSTRUCTIONS:-  This section consist of (8) questions.  Write a reliable hand write DIRTY WORK IS NOT ALLOWED.  Four marks will be awarded for a correct answered question.  Each question carries five (5) Marks 7. Enumerate five (5) adverse effects of antituberculosis drugs;- (5 marks) i. _________________________________________________________________ ii. _________________________________________________________________ iii. _________________________________________________________________ iv. _________________________________________________________________ v. _________________________________________________________________ 8. Mention three (3) classes of antimalarial drugs depending on the stage of the disease;- (3 marks) i. _________________________________________________________________ ii. _________________________________________________________________ iii. _________________________________________________________________ 9. What happen when alcohol is taken together with following drugs? (5 marks) i. Captopril _________________________________________________________________ ii. Tinidazole _________________________________________________________________ iii. Cycloserine _________________________________________________________________ iv. Promethazine _________________________________________________________________ v. Prazquantel _________________________________________________________________ 10. Give out six (6) antihelminthes drugs;- (6 marks) i. __________________________________________________________________ ii. __________________________________________________________________ iii. __________________________________________________________________ iv. __________________________________________________________________ v. __________________________________________________________________ vi. __________________________________________________________________ 6 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ 11. Enlist six (6) drugs which interact with Artesunate and Artemether;- (6 marks) i. __________________________________________________________________ ii. __________________________________________________________________ iii. __________________________________________________________________ iv. __________________________________________________________________ v. __________________________________________________________________ vi. __________________________________________________________________ 12. Enumerate four (4) viruses in which topical antiviral are active against them;- (4 marks) i. __________________________________________________________________ ii. __________________________________________________________________ iii. __________________________________________________________________ iv. __________________________________________________________________ 13. List down six (6) nucleoside reverse transcriptase inhibitors drugs;- (6 marks) i. __________________________________________________________________ ii. __________________________________________________________________ iii. __________________________________________________________________ iv. __________________________________________________________________ v. __________________________________________________________________ vi. __________________________________________________________________ 14. Mention five (5) composition of Anusol suppository or ointment;- (5 marks) i. __________________________________________________________________ ii. __________________________________________________________________ iii. __________________________________________________________________ iv. __________________________________________________________________ v. __________________________________________________________________ 7 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ SECTION E: GUIDED ESSAY QUESTIONS (30 MARKS) INSTRUCTIONS;- This section consists of two (2) questions which are supposed to be answered in a narrative way. Write your answer on the empty pages of this question paper; each question should start on a new page. 15. Explain side effects and adverse effects of anti-acids and anti-ulcers drugs;- (seven points) 16. With examples describe six (6) classes of essential medicine used for management of different cardiovascular disorders;- 8 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023  NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ Qn. Answers For official use. 9 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ 10 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ 11 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ 12 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023 NACTVET REG NUMBER _______________ EXAMINATION NUMBER ______________________ 13 | P a g e PST 04211Basic pharmacology continuous assessment two theory question paper JUNE 2023