Pharmacology (Mansoura University) 20XX (PDF)

 β2 a agonists: use high dose d by inh halation.  Add d ipratropiium bromide by inh halation to the β2 a agonists.  Hyd one: 200 mg drocortiso m i.v. / 6hss.  Con nsider a single dose of IV m...

 β2 a agonists: use high dose d by inh halation.  Add d ipratropiium bromide by inh halation to the β2 a agonists.  Hyd one: 200 mg drocortiso m i.v. / 6hss.  Con nsider a single dose of IV magnesiium sulpphate (1.2-2 g over 20 2 min) to patients who w faile ed to respond to ini tial inha aled bronchodilatoor therapy.  Corrrection of acidosis and dehyd dration by i.v. fluid ds. Part 3 3: Oxy ygen therapy █ Bas sic inform mation ▌Arteriial blood gases g (AB BG): norma al values and a interp pretation Param meter Normal range r IInterpreta ation pH 7.34 – 7.4 44 s ↓ binding of O2 to H  Acidosis Hb (tissue hypoxia) h s ↑ binding  Alkalosis g of O2 to H Hb. Arterial O2 94 –100 %  At open air, SaO2 must be > 94% and PaO2 P saturatiion at >80 mmm Hg (or 10..6 kPa). ambien nt air  Hypoxeemia means s SaO2 < 990% and/or PaO2 SaO2 48 hours can damage alveolar membrane and cause alveolar edema. 243