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CleanlyBoston

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Mansoura

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oxygen therapy pharmacology clinical medicine respiratory system

Summary

This document discusses oxygen therapy, including considerations for arterial blood gases and the interpretation of parameters like pH, arterial O2 saturation, and PaO2. It also details acute and chronic hypoxic conditions and the monitoring and stopping procedures for oxygen therapy.

Full Transcript

 β2 a agonists: use high dose d by inh halation.  Add d ipratropiium bromide by inh halation to the β2 a agonists.  Hyd one: 200 mg drocortiso m i.v. / 6hss.  Con nsider a single dose of IV m...

 β2 a agonists: use high dose d by inh halation.  Add d ipratropiium bromide by inh halation to the β2 a agonists.  Hyd one: 200 mg drocortiso m i.v. / 6hss.  Con nsider a single dose of IV magnesiium sulpphate (1.2-2 g over 20 2 min) to patients who w faile ed to respond to ini tial inha aled bronchodilatoor therapy.  Corrrection of acidosis and dehyd dration by i.v. fluid ds. Part 3 3: Oxy ygen therapy █ Bas sic inform mation ▌Arteriial blood gases g (AB BG): norma al values and a interp pretation Param meter Normal range r IInterpreta ation pH 7.34 – 7.4 44 s ↓ binding of O2 to H  Acidosis Hb (tissue hypoxia) h s ↑ binding  Alkalosis g of O2 to H Hb. Arterial O2 94 –100 %  At open air, SaO2 must be > 94% and PaO2 P saturatiion at >80 mmm Hg (or 10..6 kPa). ambien nt air  Hypoxeemia means s SaO2 < 990% and/or PaO2 SaO2 48 hours can damage alveolar membrane and cause alveolar edema. 243

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