Morphine Sulfate PDF

GENERIC NAME morphine sulfate CLASSES Narcotic analgesic Narcotic agonist STANDARD SUPPLIES Vial Ampule MECHANISMS OF ACTION Alleviates pain by depressing the central nervous system Depresses brainstem respiratory centers Decreases venous return to the heart Decreases preload Decreases afterload IND...

GENERIC NAME morphine sulfate CLASSES Narcotic analgesic Narcotic agonist STANDARD SUPPLIES Vial Ampule MECHANISMS OF ACTION Alleviates pain by depressing the central nervous system Depresses brainstem respiratory centers Decreases venous return to the heart Decreases preload Decreases afterload INDICATIONS Pain management Chest pain and/or signs and symptoms suggestive of the acute coronary syndrome Acute cardiogenic pulmonary edema CONTRAINDICATIONS Known hypersensitivity to the drug Head injury Decreased level of consciousness Hemodynamically significant hypotension ADVERSE REACTIONS/SIDE EFFECTS Central nervous system depression Respiratory depression Respiratory arrest Hypotension Bradycardia Tachycardia Dysrhythmias Syncope Dyspnea Nausea Vomiting MORPHINE SULFATE 1 ROUTES OF ADMINISTRATION IV IO IM ONSETS OF ACTION IV/IO: Immediate IM: 10 to 30 minutes ADULT DOSAGES 1.0 to 4.0 mg increments over 1 to 5 minutes PEDIATRIC DOSAGES 0.1 to 0.2 mg/kg SPECIAL CONSIDERATIONS The peak effect of IV/IO administration of the drug is 20 minutes The duration of IV/IO administration of the drug is 2 to 4 hours The peak effect of IM administration of the drug is 30 to 60 minutes The duration of IM administration of the drug is 4 to 5 hours Respiratory arrest/depression can be reversed by naloxone (Narcan®) The drug can cross the placental barrier MORPHINE SULFATE 2