Biology 1260 Midterm Prep (PDF)
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This document is a study guide for a midterm exam. It covers various topics related to human biology, including urinary system anatomy and physiology, nephron structure and function, membrane transport, and basic neuroanatomy. The guide provides specific details on organs, processes, and key structures.
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## BIOLOGY 1260 STUDY GUIDE ### Urinary System Anatomy and Histology - Identify the organs of the urinary system. - Describe the location, tissue composition, and function of the: - Renal capsule - Adipose capsule - Renal fascia - Identify, on the kidney, the location of the: - Ren...
## BIOLOGY 1260 STUDY GUIDE ### Urinary System Anatomy and Histology - Identify the organs of the urinary system. - Describe the location, tissue composition, and function of the: - Renal capsule - Adipose capsule - Renal fascia - Identify, on the kidney, the location of the: - Renal cortex - Renal medulla - Renal papilla - Renal column - Renal pelvis - Describe the location, tissue composition of the: - Ureters - Bladder - Urethra - Define transitional epithelium. - Define trigone. - Compare and contrast the male and female urethra. ### Nephron Anatomy and Histology - Briefly list the functions of the kidneys. - Identify the following blood vessels: - Renal artery/vein - Segmental arteries - Interlobar arteries/veins - Arcuate arteries/veins - Cortical radiate arteries/veins - Afferent arteriole - Glomerular capillaries - Efferent arteriole - Peritubular capillaries - Describe, in detail, the renal corpuscle, to include: - Components - Filtration membrane (endothelium + basement membrane + podocyte) - Define renin. - Compare and contrast glomerular filtration, tubular reabsorption, and tubular secretion. - Compare and contrast glomerular capillaries and the typical capillaries discussed in BIOL 1160. - Describe the process of glomerular filtration to include: - Structures involved - GBHP - CHP - BCOP - COP - The net direction of fluid flow ### Membrane Transport Review - Distinguish between active and passive transport. - Predict the permeability of the plasma membrane to the following molecules: - Small, non-polar gases (e.g., O2, CO2) - Ions - Large, polar molecules (e.g., glucose, amino acids) - Compare and contrast the following transporters: - Channels - Carrier proteins - Pumps - Symporters - Antiporters - Describe the typical arrangement of ions around the cell membrane, in particular, Na+, K+, etc. ### Reabsorptive Pathways in the Nephron - Distinguish between paracellular and transcellular transport. - Describe, in detail, the mechanism of reabsorption (including relevant molecule movements and transport proteins) of the following: - Na+/Glc pathway in PCT - H20 in the PCT - Lipid-soluble substances in the PCT - Cl-, Ca2+, K+ and urea in the PCT - Na+, Cl-, K+, Ca2+, Mg2+ in the Ascending limb - Na+, Cl- and Ca2+ in the early DCT - Na+ and K+ in the late DCT/CD - Define aquaporin. - Clearly distinguish between obligatory and facultative water reabsorption, to include: - Location in nephron - Water permeability of cells involved in process - Hormones involved (if any) ## BIOLOGY 1260 - Week 3 Study Guide ### Part 1 - Spinal Cord Anatomy - For a spinal cord model, be able to identify the: - Spinal nerve, dorsal root ganglion, anterior root of spinal nerve - Lateral white column, anterior white column, posterior white column, posterior gray horn, anterior gray horn, anterior median fissure, gray commissure, central canal, posterior median sulcus, etc - Distinguish between sensory and motor tracts. - Describe a basic reflex arc and relate to the anatomical landmarks of the spinal cord. ### Part 2 - Brain Development - Define neurulation. - Define cerebrospinal fluid and describe its appearance and contents. - Be able to clearly identify each individual component of the ventricular system: lateral ventricles, intraventricular foramen, third ventricle, aqueduct of the midbrain, fourth ventricle, lateral aperture, central canal. - What are the functions of cerebrospinal fluid? ### Part 3 - The Brainstem - Be able to physically identify the following structures/landmarks: - Cerebellum - Medulla Oblongata - Pons - Midbrain - In the medulla oblongata, identify the following structures/landmarks: - Olive - Pyramids - Decussation of pyramids - Inferior Olivary nuclei (include function in your description) - In the pons, describe the relevant structures. - In the midbrain, identify the following structures: - Thalamus - Hypothalamus - Cerebral peduncle - Superior colliculus (with function) - Inferior colliculus (with function) - Describe, in detail, the reticular activating system (RAS). ### Part 4 - The Cerebellum and Diencephalon - Locate the cerebellum. - Briefly describe the functions of the cerebellum, thalamus, and hypothalamus. - Identify the roles for the hypothalamus in human homeostatic regulation. - Describe/identify the pineal gland. What is its function? ### Part 5 - The Cerebrum - Where is the cerebrum? What is its function? Cerebral cortex? - Define gyrus and sulcus. - Clearly identify the following landmarks on the brain: - Frontal lobe - Parietal lobe - Occipital lobe - Temporal lobe - Longitudinal fissure - Central Sulcus - Precentral gyrus - Postcentral gyrus - Parieto-occipital sulcus - Insula - Lateral cerebral sulcus - Transverse fissure - Distinguish between projection tracts, commissural tracts, and projection tracts. - Define primary somatosensory area and primary motor area. - Define sensory and motor homunculus. - Locate the primary gustatory, auditory, and visual areas of the cerebral cortex. ### Part 6 - The Meninges, etc - Recall the overview of the organization of the nervous system to include: Somatic Nervous System, Autonomic Nervous System, and Enteric Nervous System. - Distinguish between the CNS and PNS. - Define the following structures of the spinal meninges: - Dura mater - Arachnoid mater - Pia Mater - Epidural space - Subarachnoid space - Distinguish between the periosteal and meningeal layers of the brain. - Define superior sagittal sinus. - Define/identify the following extensions of dura mater in the brain: - Falx cerebri - Superior sagittal sinus (dural venous sinuses) - Straight sinus - Tentorium - Falx cerebelli ## Week 4 Study Guide ### Part 1 - Introduction to Sensation - Distinguish between sensation and perception. - Briefly distinguish between the general and special senses. - Define somatic sense; define visceral sense. - Define first order neuron - and describe the 3 types of interactions between first order neurons and the associated sensory receptors. - Define interoceptor, exteroceptor, proprioceptor. - Distinguish between the stimuli detected by mechano-, thermos-, noci-, chemo-, photo-, and osmo-receptors. - Define adaptation. Distinguish between rapidly adapting receptors and slowly adapting receptors. - Describe a typical somatic sensory pathway to include: - First order neuron. - Second order neuron (+ decussation). - Third Order neuron. - Describe a typical somatic motor pathway to include the following definitions: - LMN. - Local Circuit Neuron. - Upper Motor Neuron. - Basal Nuclei. - Distinguish between a direct and indirect motor pathway. - Define corticospinal tract and distinguish between the anterior and lateral corticospinal tracts. - Describe the organization of the nervous system to include: PNS, ANS, Sympathetic Branch, Afferent division, efferent division. - Clearly distinguish between the sympathetic and parasympathetic branches of the autonomic nervous system. - Clearly distinguish between somatic and autonomic pathways. - Define the following terms and relate to the ANS: - Thoracolumbar division - Craniosacral division - For the sympathetic/thoracolumbar division, identify the following: - Ventral ramus - Gray ramus communicans - White ramus communicans - Describe the 3 typical pathways of sympathetic innervation. - Define visceral reflex. ## BIOL 1260 - Week 5 Study Guide - Identify the following structures on the eye's surface: palpebral fissure, lateral commissure, medial commissure, lacrimal caruncle, sclera, pupil. - Describe, in detail, the lacrimal apparatus. - List the components of a typical tear. - Identify the extrinsic eye muscles. - For the internal eye, be able to identify/describe in detail, the fibrous layer, vascular layer, and inner layer. Include the blindspot, anterior/posterior poles, iris, cornea, ciliary body, ciliary zonule, macula lutea. - Clearly distinguish between rods and cones. - Define bipolar cell; ganglion cell. - Define rhodopsin. - Define retinal. - Describe, in detail, the signalling pathway that results in phototransduction, starting with rhodopsin and ending with activation of the ganglion cell. - Distinguish between emmetropic, myopic, and hyperopic eyes. - Describe, in detail, the olfactory epithelium. - Describe, in detail, the signalling pathway that results in olfaction. - Describe the arrangement of a typical taste bud. - List the 5 flavours. - Describe the signalling pathway that results in taste. - Describe the anatomy of the ear and be able to identify: external auditory canal, lobule, tympanic membrane, malleus, incus, stapes, cochlea. - Define the organ of corti (Spiral organ). - Distinguish between the semicircular canals and the otolith organs. - Describe the sensory pathways for each special sense as provided in the lecture video.