Metabolic Syndrome PowerPoint PDF
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Uploaded by PrivilegedNephrite6959
Tabriz University of Medical Sciences
Dr. Elnaz Shaseb
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Summary
This PowerPoint presentation details the concept of metabolic syndrome, also known as insulin resistance syndrome. It explores the links between obesity, particularly abdominal obesity, and the development of type 2 diabetes and cardiovascular disease (CVD), emphasising the role of insulin resistance in these conditions. It also defines metabolic syndrome using ATP III criteria.
Full Transcript
Metabolic syndrome (insulin resistance syndrome or syndrome X) By: Dr. Elnaz Shaseb Assistant Professor of Clinical Pharmacy INTRODUCTION Obesity, particularly abdominal obesity, is associated with resistance to the effects of insul...
Metabolic syndrome (insulin resistance syndrome or syndrome X) By: Dr. Elnaz Shaseb Assistant Professor of Clinical Pharmacy INTRODUCTION Obesity, particularly abdominal obesity, is associated with resistance to the effects of insulin on peripheral glucose and fatty acid utilization, often leading to type 2 diabetes mellitus. Insulin resistance, the associated hyperinsulinemia and hyperglycemia, and adipocyte cytokines (adipokines) may also lead to vascular endothelial dysfunction, an abnormal lipid profile, hypertension, and vascular infammation, all of which promote the development of atherosclerotic cardiovascular disease (CVD). INTRODUCTION The co-occurrence of metabolic risk factors for both type 2 diabetes and CVD (abdominal obesity, hyperglycemia, dyslipidemia, and hypertension) suggested the existence of a "metabolic syndrome" DEFINITION ATP III criteria define metabolic syndrome as the presence of any three of the following five traits: Abdominal obesity, defined as a waist circumference ≥102 cm (40 in) in men and ≥88 cm (35 in) in women Serum triglycerides ≥150 mg/dL (1.7 mmol/L) or drug treatment for elevated triglycerides Serum high-density lipoprotein (HDL) cholesterol
