Bio 305 Citric Acid Cycle Lecture PDF

Bio 305 Citric Acid Cycle Mitochondrial Structure and Functions Outer membrane –Porins –Permeable to metabolites and small proteins Inner membrane –Invaginates into cristae –Lots of specific transporters –e- transport components –ATP synthase Intermembrane space –Nucleotide phosphorylation Matrix –S...

Bio 305 Citric Acid Cycle Mitochondrial Structure and Functions Outer membrane –Porins –Permeable to metabolites and small proteins Inner membrane –Invaginates into cristae –Lots of specific transporters –e- transport components –ATP synthase Intermembrane space –Nucleotide phosphorylation Matrix –Site of most biochemistry –Contains DNA, ribosomes –Protein synthesis –Oxidize pyruvate & Kreb’s cycle Aerobic Respiration Oxygen Present Loading… Pyruvate oxidation Loading… 8 steps Produces 3 NADH, 1 FADH2, and 1 GTP for each acetyl CoA 2CO2 is released NADH and FADH2 go to ETC GTP is converted into ATP Essential Cell Biology, Fifth Edition Copyright © 2019 W. W. Norton & Company Essential Cell Biology, Fifth Edition Copyright © 2019 W. W. Norton & Company