Lecture 8
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Questions and Answers

Where does pyruvate oxidation take place?

  • Outer membrane
  • Inner membrane
  • Intermembrane space
  • Matrix (correct)
  • Which component of the mitochondria is responsible for oxidizing pyruvate and the Kreb's cycle?

  • Outer membrane
  • Matrix (correct)
  • Inner membrane
  • Intermembrane space
  • What is the function of the outer membrane of the mitochondria?

  • Contain specific transporters for e- transport components
  • Protein synthesis
  • Site of most biochemistry
  • Permeable to metabolites and small proteins (correct)
  • Which part of the mitochondria contains DNA and ribosomes for protein synthesis?

    <p>Matrix</p> Signup and view all the answers

    What is the role of NADH and FADH2 in aerobic respiration?

    <p>Go to electron transport chain (ETC)</p> Signup and view all the answers

    Which component of the mitochondria is responsible for invaginating into cristae?

    <p>Inner membrane</p> Signup and view all the answers

    What is the main function of porins in the outer mitochondrial membrane?

    <p>Permeable to metabolites and small proteins</p> Signup and view all the answers

    During pyruvate oxidation, how many NADH molecules are produced for each acetyl CoA?

    <p>3</p> Signup and view all the answers

    Which part of the mitochondria serves as the site for nucleotide phosphorylation?

    <p>Intermembrane space</p> Signup and view all the answers

    What happens to the GTP produced during pyruvate oxidation?

    <p>Converted into ATP</p> Signup and view all the answers

    During pyruvate oxidation, 2CO2 is released along with the production of 3 NADH, 1 FADH2, and 1 GTP for each acetyl CoA. The NADH and FADH2 molecules go to the ETC while the GTP is converted into ______

    <p>ATP</p> Signup and view all the answers

    The inner membrane of the mitochondria invaginates into cristae and contains lots of specific transporters, electron transport components, and ATP synthase. This membrane is impermeable to metabolites and small proteins, unlike the outer membrane that is permeable due to the presence of ______

    <p>Porins</p> Signup and view all the answers

    The intermembrane space of the mitochondria is the site of nucleotide phosphorylation, while the matrix is where most of the biochemistry occurs. The matrix also contains DNA, ribosomes, and is involved in protein synthesis and the oxidation of pyruvate & the Kreb’s cycle. Therefore, the matrix is critical for various cellular functions that require energy production through aerobic respiration when ______ is present

    <p>Oxygen</p> Signup and view all the answers

    Pyruvate oxidation in the mitochondria involves 8 steps and results in the production of 3 NADH, 1 FADH2, and 1 GTP for each acetyl CoA. This process is essential for generating energy in the form of ATP through the electron transport chain. The NADH and FADH2 molecules are crucial for transferring electrons in the ETC, ultimately leading to ATP production. The GTP produced is directly converted into ______

    <p>ATP</p> Signup and view all the answers

    The mitochondrial inner membrane plays a crucial role in electron transport and ATP synthesis. This membrane is packed with specific transporters, electron transport components, and ATP synthase, which collectively contribute to the generation of ATP through oxidative phosphorylation. Additionally, the inner membrane is where the electrons from NADH and FADH2 are shuttled to create a proton gradient necessary for ATP production. The inner membrane's unique structure with invaginations into cristae enhances its surface area and accommodates various enzymes and complexes involved in ______

    <p>oxidative phosphorylation</p> Signup and view all the answers

    What is the primary function of the intermembrane space in mitochondria?

    <p>Nucleotide phosphorylation</p> Signup and view all the answers

    Which part of the mitochondria is responsible for converting GTP into ATP during pyruvate oxidation?

    <p>Matrix</p> Signup and view all the answers

    What role do porins play in the outer mitochondrial membrane?

    <p>Regulate metabolite transport</p> Signup and view all the answers

    During pyruvate oxidation, what happens to the 2CO2 that is released?

    <p>It exits the mitochondria</p> Signup and view all the answers

    Which component of the mitochondria invaginates into cristae and contains specific transporters and electron transport components?

    <p>Inner membrane</p> Signup and view all the answers

    The inner mitochondrial membrane is impermeable to metabolites and small proteins.

    <p>False</p> Signup and view all the answers

    During pyruvate oxidation, 2 ATP molecules are produced for each acetyl CoA.

    <p>False</p> Signup and view all the answers

    The NADH and FADH2 produced during pyruvate oxidation directly enter the Electron Transport Chain (ETC).

    <p>True</p> Signup and view all the answers

    The matrix of the mitochondria is involved in the oxidation of lipids for energy production.

    <p>False</p> Signup and view all the answers

    Porins in the outer mitochondrial membrane are responsible for maintaining impermeability to ions.

    <p>False</p> Signup and view all the answers

    During aerobic respiration, what happens to the pyruvate from glycolysis? Where does this reaction occur? The pyruvate undergoes conversion into acetyl CoA through oxidative decarboxylation. This reaction occurs in the ______.

    <p>mitochondrial matrix</p> Signup and view all the answers

    What enzyme complex is used to convert pyruvate? What are the products of pyruvate decarboxylation? The enzyme complex used is the pyruvate dehydrogenase complex. The products are one molecule of acetyl CoA, one molecule of NADH, and one molecule of ______.

    <p>CO2</p> Signup and view all the answers

    What process oxidizes acetyl CoA and where does it occur? Acetyl CoA is oxidized in the ______ cycle, which occurs in the mitochondrial matrix.

    <p>citric acid</p> Signup and view all the answers

    What molecule does acetyl CoA bind to when it enters the citric acid cycle? What molecule is formed? Acetyl CoA binds to oxaloacetate, forming ______.

    <p>citrate</p> Signup and view all the answers

    How many reactions occur in the citric acid cycle? What products are made by the citric acid cycle? ______ reactions occur in the citric acid cycle. The products include three molecules of NADH, one molecule of FADH2, one molecule of ATP (or GTP), and two molecules of ______.

    <p>Eight, CO2</p> Signup and view all the answers

    What molecule must be re-generated for the citric acid cycle to continue? Acetyl CoA must be re-generated for the citric acid cycle to ______.

    <p>continue</p> Signup and view all the answers

    The enzyme complex used to convert pyruvate is the pyruvate dehydrogenase ______.

    <p>complex</p> Signup and view all the answers

    The process that oxidizes acetyl CoA is the ______ cycle.

    <p>citric acid</p> Signup and view all the answers

    Acetyl CoA binds to ______ when it enters the citric acid cycle.

    <p>oxaloacetate</p> Signup and view all the answers

    Where does the conversion of pyruvate into acetyl CoA occur during aerobic respiration?

    <p>Mitochondrial matrix</p> Signup and view all the answers

    What are the products of pyruvate decarboxylation?

    <p>One molecule of acetyl CoA, one molecule of NADH, and one molecule of CO2</p> Signup and view all the answers

    Where does the citric acid cycle occur in the cell?

    <p>Mitochondrial matrix</p> Signup and view all the answers

    What molecule does acetyl CoA bind to when it enters the citric acid cycle?

    <p>Oxaloacetate</p> Signup and view all the answers

    How many reactions typically occur in the citric acid cycle?

    <p>Eight reactions</p> Signup and view all the answers

    Which molecule needs to be re-generated for the citric acid cycle to continue?

    <p>Acetyl CoA</p> Signup and view all the answers

    What is the primary function of the mitochondrial matrix?

    <p>Protein synthesis</p> Signup and view all the answers

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