41 Questions
Where does pyruvate oxidation take place?
Matrix
Which component of the mitochondria is responsible for oxidizing pyruvate and the Kreb's cycle?
Matrix
What is the function of the outer membrane of the mitochondria?
Permeable to metabolites and small proteins
Which part of the mitochondria contains DNA and ribosomes for protein synthesis?
Matrix
What is the role of NADH and FADH2 in aerobic respiration?
Go to electron transport chain (ETC)
Which component of the mitochondria is responsible for invaginating into cristae?
Inner membrane
What is the main function of porins in the outer mitochondrial membrane?
Permeable to metabolites and small proteins
During pyruvate oxidation, how many NADH molecules are produced for each acetyl CoA?
3
Which part of the mitochondria serves as the site for nucleotide phosphorylation?
Intermembrane space
What happens to the GTP produced during pyruvate oxidation?
Converted into ATP
During pyruvate oxidation, 2CO2 is released along with the production of 3 NADH, 1 FADH2, and 1 GTP for each acetyl CoA. The NADH and FADH2 molecules go to the ETC while the GTP is converted into ______
ATP
The inner membrane of the mitochondria invaginates into cristae and contains lots of specific transporters, electron transport components, and ATP synthase. This membrane is impermeable to metabolites and small proteins, unlike the outer membrane that is permeable due to the presence of ______
Porins
The intermembrane space of the mitochondria is the site of nucleotide phosphorylation, while the matrix is where most of the biochemistry occurs. The matrix also contains DNA, ribosomes, and is involved in protein synthesis and the oxidation of pyruvate & the Kreb’s cycle. Therefore, the matrix is critical for various cellular functions that require energy production through aerobic respiration when ______ is present
Oxygen
Pyruvate oxidation in the mitochondria involves 8 steps and results in the production of 3 NADH, 1 FADH2, and 1 GTP for each acetyl CoA. This process is essential for generating energy in the form of ATP through the electron transport chain. The NADH and FADH2 molecules are crucial for transferring electrons in the ETC, ultimately leading to ATP production. The GTP produced is directly converted into ______
ATP
The mitochondrial inner membrane plays a crucial role in electron transport and ATP synthesis. This membrane is packed with specific transporters, electron transport components, and ATP synthase, which collectively contribute to the generation of ATP through oxidative phosphorylation. Additionally, the inner membrane is where the electrons from NADH and FADH2 are shuttled to create a proton gradient necessary for ATP production. The inner membrane's unique structure with invaginations into cristae enhances its surface area and accommodates various enzymes and complexes involved in ______
oxidative phosphorylation
What is the primary function of the intermembrane space in mitochondria?
Nucleotide phosphorylation
Which part of the mitochondria is responsible for converting GTP into ATP during pyruvate oxidation?
Matrix
What role do porins play in the outer mitochondrial membrane?
Regulate metabolite transport
During pyruvate oxidation, what happens to the 2CO2 that is released?
It exits the mitochondria
Which component of the mitochondria invaginates into cristae and contains specific transporters and electron transport components?
Inner membrane
The inner mitochondrial membrane is impermeable to metabolites and small proteins.
False
During pyruvate oxidation, 2 ATP molecules are produced for each acetyl CoA.
False
The NADH and FADH2 produced during pyruvate oxidation directly enter the Electron Transport Chain (ETC).
True
The matrix of the mitochondria is involved in the oxidation of lipids for energy production.
False
Porins in the outer mitochondrial membrane are responsible for maintaining impermeability to ions.
False
During aerobic respiration, what happens to the pyruvate from glycolysis? Where does this reaction occur? The pyruvate undergoes conversion into acetyl CoA through oxidative decarboxylation. This reaction occurs in the ______.
mitochondrial matrix
What enzyme complex is used to convert pyruvate? What are the products of pyruvate decarboxylation? The enzyme complex used is the pyruvate dehydrogenase complex. The products are one molecule of acetyl CoA, one molecule of NADH, and one molecule of ______.
CO2
What process oxidizes acetyl CoA and where does it occur? Acetyl CoA is oxidized in the ______ cycle, which occurs in the mitochondrial matrix.
citric acid
What molecule does acetyl CoA bind to when it enters the citric acid cycle? What molecule is formed? Acetyl CoA binds to oxaloacetate, forming ______.
citrate
How many reactions occur in the citric acid cycle? What products are made by the citric acid cycle? ______ reactions occur in the citric acid cycle. The products include three molecules of NADH, one molecule of FADH2, one molecule of ATP (or GTP), and two molecules of ______.
Eight, CO2
What molecule must be re-generated for the citric acid cycle to continue? Acetyl CoA must be re-generated for the citric acid cycle to ______.
continue
The enzyme complex used to convert pyruvate is the pyruvate dehydrogenase ______.
complex
The process that oxidizes acetyl CoA is the ______ cycle.
citric acid
Acetyl CoA binds to ______ when it enters the citric acid cycle.
oxaloacetate
Where does the conversion of pyruvate into acetyl CoA occur during aerobic respiration?
Mitochondrial matrix
What are the products of pyruvate decarboxylation?
One molecule of acetyl CoA, one molecule of NADH, and one molecule of CO2
Where does the citric acid cycle occur in the cell?
Mitochondrial matrix
What molecule does acetyl CoA bind to when it enters the citric acid cycle?
Oxaloacetate
How many reactions typically occur in the citric acid cycle?
Eight reactions
Which molecule needs to be re-generated for the citric acid cycle to continue?
Acetyl CoA
What is the primary function of the mitochondrial matrix?
Protein synthesis
Test your knowledge on the Citric Acid Cycle and the structure and functions of mitochondria. Learn about the components such as outer membrane, inner membrane, intermembrane space, and matrix along with their roles in aerobic respiration and pyruvate oxidation.
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