Innate defenses- The inflammatory response - Tagged.pdf

The body’s response to injury Part B – The Inflammatory response Mr Bashir Sumar School of Nursing and Midwifery  Important Copyright Notice for Western Sydney University Students The material in this presentation has been made available to you by and on behalf...

The body’s response to injury Part B – The Inflammatory response Mr Bashir Sumar School of Nursing and Midwifery  Important Copyright Notice for Western Sydney University Students The material in this presentation has been made available to you by and on behalf of Western Sydney University for your personal use and study only. The material contained in this recorded lecture is subject to copyright protection. You may not make any further copies and share the recorded lectures in whole or in part by any hardcopy, digital and or online technologies. Objectives of Part B Internal Innate Defenses: Cells and Chemicals Describe the inflammatory process. Identify several inflammatory chemicals and indicate their specific roles. Name the body’s antimicrobial substances and describe their function. Explain how fever helps protect the body.  Inflammatory Response Triggered whenever body tissues injured Prevents spread of damaging agents Disposes of cell debris and pathogens Alerts adaptive immune system Sets the stage for repair © 2013 Pearson Education, Inc.  Inflammatory Response Cardinal signs of acute inflammation: 1. Redness 2. Heat 3. Swelling 4. Pain (symptom) (Sometimes 5. Impairment of function) © 2013 Pearson Education, Inc.  Inflammatory chemical release Begins with chemicals released into ECF by injured tissues, immune cells, blood proteins Inflammatory mediators – Kinins, prostaglandins (PGs), and complement Dilate local arterioles (hyperemia) – Causes redness and heat of inflamed region Make capillaries leaky Many attract leukocytes to area Some have inflammatory roles  For further components of the Inflammatory response, read and view the following : Marieb, E.N. & Hoehn, K. (2019). Human anatomy & physiology. (11th global ed.). Harlow, UK: Pearson Education Pages 817 -819 (or 829-832 in 9 ed.) th https://www.bing.com/vid eos/search?q=components +of+the+inflammatory+res ponse&&view=detail&mid =7894322AA53F4065CCDA 7894322AA53F4065CCDA& &FORM=VRDGAR