First Year Organic Chemistry 1 (Sec 1&2) - PDF

Summary

This document is a set of lecture notes for a first-year organic chemistry course, covering various aspects of organic chemistry, including lab safety, chemical reactions and physical properties. The information is presented in a structured format with diagrams and examples. The notes give helpful insights into handling chemicals and conducting experiments safely.

Full Transcript

PHARMACEUTICAL ORGANIC CHEMISTRY DEPARTMENT Pharmaceutical organic chemistry 1 : ‫لينك شرح العملى‬ https://drive.google.com/file/d/1qKq16mplqj- FUSzIzjjWyHkFJ1M7NBzr/view?usp=drivesdk Lab safety The laboratory can be a dangerous place. Basic safety...

PHARMACEUTICAL ORGANIC CHEMISTRY DEPARTMENT Pharmaceutical organic chemistry 1 : ‫لينك شرح العملى‬ https://drive.google.com/file/d/1qKq16mplqj- FUSzIzjjWyHkFJ1M7NBzr/view?usp=drivesdk Lab safety The laboratory can be a dangerous place. Basic safety rules: Eye protection ‫حماية العين‬ goggles Safety glasses Wear appropriate protective clothing: Your clothing should cover your legs to the knees – shorts are not appropriate for the laboratory. Wear shoes that cover your feet. Sandals and open-toed shoes do not protect your feet from chemical spills and broken glass that is frequently found in the lab. Hair Longer tie back Handling chemical Symbol or label on bottle Ask ? Not guess Avoid Contact to skin Wear gloves and use spatula. Taste Never unless given sp. instructions Heating in test tube Direction Heat test tubes at an angle, directing the opening oppositely to you and other people in the laboratory. Smell Wave vapors toward face Handle hot glassware with gloves or beaker tongs Do not pipet solutions by mouth! Use a rubber suction bulb or other device to fill a pipet. Diluting Acids ‫تخفيف األحماض‬ Acid Water Not vice versa ‫وليس العكس صحيحا‬ Do not Eat ,Drink or Smoke These activities are ways by which you can accidentally ingest harmful chemicals. Splashes from skin Rinse with cold water Or PEG Corrosives ‫المواد الحارقة‬ Eye eyewash open eyelids Noxious gas Fan turn on Burners Turn off before go to next step. Wash your hand Before leaving lab ‫قبل مغادرة المعمل‬ Identification of organic 1-physical properties compounds 2-chemical reactions 3-general class reactions 4-special tests Physical properties 1-condition Solid Liquid crystal mobile powder oily amorphous viscous 2-color 1- colorless 2- colored compound 3-odour 1- odourless 2-characteristic odour  Aniline : fishy odour Acetic acid : vinegar odour Ethanol : alcoholic odour Ethyl acetate : fruity odour 4- solubility/ miscibility Solubility in water A- soluble in water Check acidity using litmus paper Acid : convert color of blue litmus paper into red. Alkali : convert color of red litmus paper into blue. Neutral : No change in colour. B- Insoluble in water Check solubility in 30% NaoH Soluble: Acid Insoluble: Check Solubility in Hcl Alkali 5-Dry heat test (ignition test) 1- Inflammability A-inflammable (Flammable) B- Non inflammable (non flammable) 2- colour of flame No Change Change in colour: if unknown contains metal as Na : Golden yellow K:Violet 3-odour of evolved gas no odour have characteristic odour 4- change of appearance Melting evaporation charring ( blacking) 5- residue : The remaining part of material No residue Residue is present Dry heat test Unknown Scheme Physical properties 1-condition: 2-color: 3-odour: 4- solubility/ miscibility: 5-Dry heat test (ignition test): 1- Inflammability 2- colour of flame 3-odour of evolved gas 4- change of appearance 5- residue : ‫لينك شرح العملى‬  https://drive.google.com/file/d/1qKq16mplqj- FUSzIzjjWyHkFJ1M7NBzr/view?usp=drivesdk Thank you

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