Antibiotic Usage In Practice PDF

ANTIBIOTIC USAGE IN PRACTICE Tony Maanum, PGY2 Infectious Disease Resident, UnityPoint Iowa Methodist Medical Center „ Understand basic foundational knowledge about the practice of infectious disease „ Determine the purpose of common antibiotics used in hospital practice OBJECTIVES FO...

ANTIBIOTIC USAGE IN PRACTICE Tony Maanum, PGY2 Infectious Disease Resident, UnityPoint Iowa Methodist Medical Center „ Understand basic foundational knowledge about the practice of infectious disease „ Determine the purpose of common antibiotics used in hospital practice OBJECTIVES FOUNDATIONAL KEY CONCEPTS „ Key document for the use of antibiotics at the institute that you are practicing at „ Antibiograms are facility specific created from recent historical data seen in the hospital (or specific practice setting) „ Shows the pattern of resistance that each pathogen has to our usual antibiotics „ “Report Card” „ These will vary greatly from different institutions around the US, so it is very important to learn the antibiogram of the institute that you practice at ANTIBIOGRAM „ Clinical Laboratory Standards Institute is CLSI, main governing body for lab processes „ They set the Minimum Inhibitory Concentrations (MIC) for antibiotics for each specific pathogen „ Incorporating new CLSI recommendations can take extended periods of time for each facility's lab to update o May take months to years depending on the lab CLSI „ The MIC is a predetermined value for each antibiotic on families of bacteria that can tell us if they are susceptible or resistant o Ex. Ceftriaxone has a maximum susceptible MIC of 1 for enterobacterales bacteria like e. coli o This means anything above it, >1, will get marked as either intermediate/dose dependent (I) or resistant (R) on the susceptibility report o Anything below this,