Connective Tissue_DTH24 GN.pdf

Connective tissue Tutor: P Lazarou Module: Biomedical Science GDC Learning Outcomes Aim: The aim of this subject is to apply to the practice of dental therapy and dental hygiene principles that derive from the biomedical, behavioural and materials sciences. Develop knowledge of the structu...

Connective tissue Tutor: P Lazarou Module: Biomedical Science GDC Learning Outcomes Aim: The aim of this subject is to apply to the practice of dental therapy and dental hygiene principles that derive from the biomedical, behavioural and materials sciences. Develop knowledge of the structures and essential functions of the connective tissues. GDC: 1.1 Intended learning outcomes Students will be able to: State the function and characteristics of connective tissue Loading… Name and describe the non-cellular substrate of connective tissue List and describe the cells of connective tissue List and describe the fibres of connective tissue Outline and classify the types of connective tissue 0 Originates from mesenchyme-middle layer of embryonic germ layers. functions : What is connective tissue? supports · and connects tissue and parts of body · protects+ repairs provides strength the body. · A group of tissues that maintain the form of the body and Transport · its organs and provide cohesion and internal support. ↳ blood water, , ions , inorganic materials. Insulation + Several types of tissues · that vary in their: Storage ↳ fat water , Density Cellularity different ~ CT cells · Being specialised Image ref: gordonstate.edu 0 Overview of Connective Tissue Water 90 % majority Cells specalised -. Loading… Fibroblasts, adipocytes, macrophages, mast cells, plasma cells, eosinophils In a matrix made up of glycoproteins, fibrous proteins and S Building glycosaminoglycans block Proteins. Extracellular matrix Fibres 0 role in important 3rd made up structure of collagen-maintaining ↓ determine tissue function. Overview continued… 1 - Gif ref: My First Animation. The& extracellular matrix is the main feature in tissues with a mechanical function (ligaments, tendon & bone) G Cells are the main feature in tissues specialised for · protection (haemopoietic tissue, blood - white blood cells) or metabolic maintenance (adipocytes, blood - red blood cells). Image ref: leeds.ac.uk Cells 0 Connective Tissue Cells Fixed cells: Fibroblasts nin Adipocytes Macrophages Mast cells Nutrifics basate ↑ Transient Cells: aze a (wonderingan Plasma cells White blood cell Eosinophils circulate in blood stream and migrate to CT for as > required immune response Cells of the connective tissues Over to you- complete the table in the workbook Non-cellular substrate 0 Gen Protein 7 polysaccharide Mix 90 % water noncellular ↑+ also enlosed fibres + cells + extracellval ↳ all secreted and matrix Extracellular matrix -.. organised by cells Gen Also known as ground substance always gelatives not. - loose or Amorphous gelatinous - material Transparent, colourless Loading… dense. Fills the spaces between cells and fibres, also enable transportation of metabolites hyaluronic acid Consists of large protein- molecule: naturally occurring. glycosoaminoglycans (GAGs) – link together making Where water larger molecules: proteoglycans which absorb water stored Good at resisting compressive forces very I due to properties AmorPHOUS ? 0 Fibres S made by fibroblasts. Spaced O ⑭ out Image ref: Wikipedia.org Fibres 0 Fibres of the Connective Tissue Secreted by fibroblasts Form a supporting network to which cells attach Three types: Elastic Collagen Reticular 0 Connective tissue fibres Elastic Collagen Reticular Look out for each of these types of fibres- different combinations make up different types of connective tissue! Images ref: histology.leeds.ac.uk stic-isolated individual branching threads - not clumped gibres within tissue. contain elastane-enables very stretchy , the elestic fibres to original state stretch return to after being Able to stretch 1 5 times gibne. of the length of the. Sx more stretchy than elastic band. Nottager) - : mode up of Collagen , most common type of fibre in CT. more resistant to stretching give strength to , where they are found , resist load and stress + breakage. Ligaments + tendons to give resilience + strength & Reticular - randomly placed Collagenes fibrill form mesh like , reticulin Act as supporting network of ST liver , lympathic, bone Marrow. Classification of Connective Tissue 0 Types of connective tissue zmain types Connective Tissue Specialised Proper Connective Tissue Loose Dense Supporting Fluid Connective Connective connective connective Tissue Tissue tissue areolar Areol reg Regul Cartil Bone Bloo Lym adipose - > ar Irrey > ar age d ph reticular Cluste Adipo Irregu I Hyaline I Comp 2 Fibrocart act se lar ilage 2 Spong Reticu Elasti 3 Elastic y  lar c 0 Classification - lymph Connective Tissue Proper: Loose connective tissue - dermis. Dense connective tissue Images ref: histology.leeds.ac.uk 0 Connective Tissue Proper acmas loosly arranged - numerous fibres. Numerous cells Appearance of loose fibres- some thin (elastin fibres) some thicker (collagen fibres) Slightly viscous fluid 0 Loose connective tissue Found in most areas of the human body Ski ·under esche Connects and supports ~ blood support other tissues by acting as vessels + - a framework. reived · gland main cell types : fibroblasts · Dental macrophages pulp ! 0 -Any white ~ t it Loose Connective tissue insulates , where energy is stored. Areolar Adipose Reticular Brown AT Generates more heat vital for new borng. *Covers *In a matrix of * Fine in m+ around found · argume Timpu muscle fibres areolar tissue- 2 branching mucous membrane types: reticular fibres nodes immune · Surrounds Mervel + *Under 1.White adipose in a semi solid redy for System tissue: store blood vessels epidermis matrix. tes t monosy ↑. *20-25% body *in/around weight *Contains reticular cells, symphocytes 0 Loose connective tissue: areolar - Skin Dental pulp Bone Image ref: ucdmc.ucdavis.edu Image ref: diseasesfix.com 0 Oral mucosa a thin Laye o f retrea Image ref: pocketdentistry.com 0 mainly elastic allows to recoil , arterial blood fibres vessels + bronchi ↑ tubes many more modified. CT Elastic fibres dense but els dense woven Dense function of less network Connective joine Collagenous of ↑ Dense TissueDense regular dense powered Collagengibers - fibres , some irregular I rregular arranged parallel. elastic ↓ fibroblasts Surrounding muscles ligaments resistant Yo I link bone-bone force joint > viscous tendons capsule bone-cartliage Muscle - dermis of Skin allows stretching but 0 Types of connective tissue Connective Tissue Specialised Proper Connective Tissue Loose Dense Supporting Fluid Connective Connective connective connective Tissue Tissue tissue Areol Regul Cartil Bone Bloo Lym ar ar age d ph Adipo Irregu Hyaline Comp lar Fibrocart act se ilage Spong Reticu Elasti Elastic y  lar c 0 Dense rows of white collage fibres Chondrocytes , arranged in small groups fought Slightly flexible Cartilage a from only fibre = collagen a paralle provide portin flexibility Firmer than other urtmovem supports tissues ↓ + relicts tension compression. - connective tissues TMJ Cells: chondrocytes (not many) within the matrix of collagen and elastic fibres 3 types: Hyaline Fibrocartilage 3 Elastic · Blood vessel walls , flexible · many elastic fibres Pinna of ear within solid matrix supports maintains struction · + epiglottis · needed · -provides strength elasticity when Image ref: Researchgate.net. 0 Temporomandibular joint I -- > fibrocartilage within disc. Image ref: bizjournals.com  Surrounded by matrix of collage fibres produce Osteocytes - strengthened - salts ; calcium + bone Image ref: youtube.com by in organic Image ref: medcell.medyale.edu phosphates. Bone · can regenerate 2 types: Compact cortical - solid dene · + · Whiteish appearance · Hard outer layer heavy-dense · Spongy Kanallaus · honey cours · pink within bone Image ref: quizlet.com Image ref: Eugraph.com 0 Blood Consists of highly specialized watery fluid: plasma Loading… Constantly circulating around the body Various blood cells within: erythrocytes, leucocytes and platelets Image ref: slideshare.net  Assessment Formative Summative Student task: Biomedical sciences Eassessment Please complete the various tasks in the Connective Tissue Workbook. You may refer to the further reading and reference lists as well as carrying out your own research 0 References/further resources Histology.Leeds.ac.uk, Classification of Connective Tissue (online) Available at: http://www.histology.leeds.ac.uk/tissue_types/connective/connective_tissue_types.php [accessed February 2021] YouTube video, Types of Connective Tissue, What is Connective Tissue_ Functions of Connective Tissue (online) Available at: https://www.youtube.com/watch?v=4HNbspnFyIE [accessed 10/03/21] Med.LibreTexts.org (2020), Types of Connective Tissue (online) Available at: https://med.libretexts.org/Bookshelves/Anatomy_and_Physiology/Book%3A_Anatomy_and_Phy siology_(Boundless)/4%3A_Organization_at_the_Tissue_Level/4.3%3A_Connective_Tissue/4.3 B%3A__Types_of_Connective_Tissue [accessed 15/03/21] Waugh,A Grant, A.(2018), Ross & Wilson Anatomy and Physiology. Thirteenth Edition. London: Elsevier, Pages 49-53.