boptm-bo-104-biochemistry-(ocular-and-general)-2010.pdf

Name : …………………………………………………………… Roll No. : ………………………………………………………… Invigilator's Signature : ……………………………………….. CS/B.OPTM/SEM-1/BO-104/2010-11...

Name : …………………………………………………………… Roll No. : ………………………………………………………… Invigilator's Signature : ……………………………………….. CS/B.OPTM/SEM-1/BO-104/2010-11 2010-11 BIOCHEMISTRY ( OCULAR & GENERAL ) Time Allotted : 3 Hours Full Marks : 70 The figures in the margin indicate full marks. Candidates are required to give their answers in their own words http://www.makaut.com/ as far as practicable. GROUP – A ( Objective Type Questions ) 1. Answer any ten of the following : 10 × 1 = 10 A) Choose the correct alternatives for the following : i) All are hormones secreted from anterior pituitary except a) growth hormone b) ACTH c) L.H. d) vasopressin. ii) Scurvy occurs due to a) Vitamin A b) Vitamin B 12 c) Ascorbic acid d) Vitamin D. 1155 [ Turn over http://www.makaut.com/  CS/B.OPTM/SEM-1/BO-104/2010-11 iii) The rate limiting enzyme in glycogenolysis is a) glycogen phosphorylase b) glucan transferase c) phosphoglucomutase d) none of these. B) Fill in the blank : iv) The bond that stabilises the secondary structure of protein is …………………. http://www.makaut.com/ C) Choose the correct alternatives for the following : v) Ellipsoid and myoid of rod is present in a) outer segment b) inner segment c) medial segment d) peripheral segment. vi) The soluble proteins present in crystalline lens are a) albuminoids b) crystallines c) gelatins d) all of these. vii) The innermost layer of the tear film is a) protein layer b) lipid layer c) aqueous layer d) mucin layer. viii) The glycosaminoglycan present in cornea is a) hyaluronic acid b) dermatan sulphate c) keratan sulphate d) heparin. 1155 2 http://www.makaut.com/  CS/B.OPTM/SEM-1/BO-104/2010-11 ix) During cataract formation , there is a) accumulation of sodium ions in the lens b) accumulation of sodium ions and water c) increase in ratio of insoluble to soluble proteins d) all of these e) none of these. x) Capillary wall in the ciliary processes http://www.makaut.com/ a) allows most proteins to pass out b) acts as impermeable membrane c) acts as semipermeable membrane d) none of these. D) Fill in the blank : xi) Rhodopsin consists of a colourless protein called …………………. GROUP – B ( Short Answer Type Questions ) Write short notes on any three of the following. 3 × 5 = 15 2. Oxygen transport mechanism of haemoglobin. 3. Effect of pH on oxygen. 4. Dissociation curve. 5. Estrogen ( hormone ). 6. Allosteric enzyme. 1155 3 [ Turn over http://www.makaut.com/  CS/B.OPTM/SEM-1/BO-104/2010-11 GROUP – C ( Long Answer Type Questions ) Answer any three of the following. 3 × 15 = 45 7. a) What are hormones ? Briefly outline their chemical characteristics. Explain mineralocorticoid hormones. 1 1 b) Illustrate Lineweaver-Burk plot. 72 + 7 2 8. What are water soluble vitamins ? Discuss their sources and the disease caused by their deficiency. http://www.makaut.com/ 9. Explain the biochemical basis of cataract formation in old people ( senile cataract ). 10. Write notes on the following : 3×5 a) Carbohydrate metabolism. b) HMP shunt. c) Nitrogen balance. 1155 4 http://www.makaut.com/