CNS: Brain Structures, Neurochemical systems & Functions (PDF)
Document Details
Uploaded by ToughestAntagonist
University of Sunderland
Dr Abdel Ennaceur
Tags
Summary
This document provides an introduction to the central nervous system (CNS), focusing on brain structures, neurochemical systems, and functions. It details the composition of the brain, including nerve cells, glial cells, and cerebrospinal fluid. The document also covers the surface anatomy and main nerve tracts, offering detailed descriptions of neurons, ganglia, nuclei, tracts, and nerves.
Full Transcript
... ... ... . ... ﺍﻟﻨﺎ ﺻﺮ ... Brain Structures, Neurochemical systems & Functions Slide 1 of 76 ﺻﺮ ﻋﺒﺪ ﺻﺮ ﻨﺎ The brain with the spinal cord makes up the central nervous system (CNS). .... ﺻﺮ Slide 2 of 76 ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍ ﻟﻘﺎ ...
... ... ... . ... ﺍﻟﻨﺎ ﺻﺮ ... Brain Structures, Neurochemical systems & Functions Slide 1 of 76 ﺻﺮ ﻋﺒﺪ ﺻﺮ ﻨﺎ The brain with the spinal cord makes up the central nervous system (CNS). .... ﺻﺮ Slide 2 of 76 ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘﺎ .... .... .... ... ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻨﺎ .... . .... ... ﺩﺭ ﺍﻟﻘﺎ .... .... ﺍﻟﻨﺎ .... . . ... ﺩﺭ £ﻋﺒ ﺎﺻ ﺍﻟﻨ ... . ... ﻋﺒ ﺮ$ ﻋﺒﺪ ... ﺎ ﺩﺭ ﺍﻟﻘ ﺍﻟﻨ ﺻﺮ ﺮ$ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ . ... ... ... ﺍﻟﻨﺎ ﺎﺻ ﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ ... ... ﺻﺮ .. ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ ﺪ ﺍﻟﻘ ﺪﺍ ﻟﻘﺎ ﺻﺮ . ... ﺍﻟﻨﺎ .. .. ... ... ﻟﻘﺎ ﺩﺭ ... ... ﺪﺍ ﻋﺒ . ... ... . ... ﺍﻟﻨﺎ ... ... . ... . ... ... ... ... ... .. ... ... ... .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺻﺮ ﻋﺒ ﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ Introduction ﺻﺮ ﻋﺒﺪ .... . .. ... . ... ... ... ... . . ... ... . ... ... ... ... ... . ﻋﺒﺪ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ .... ... ... ... ... ... ﺍﻟﻨﺎ .. . ... hemispheres, ﺍ ﻟﻘﺎ ﺍﻟﻨﺎ ﺻﺮ &\ ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ... ... ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒﺪ ﺩﺭ ﺍ ﻟﻘﺎ ﺮ$ ﺍ ﻟﻘﺎ ﺩﺭ .. ﺻﺮ ﺍﻟﻨﺎ .... . ... ... .. ... ... ... .... ﺩﺭ ﺍﻟﻘ ﺻﺮ ﻋﺒ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎ ﺻﺮ PHA 112 – CNS : Brain Structures and Functions ﺭ ﺍﻟ PHA 112 – CNS : Brain Structures and Functions ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺩﺭ &\ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ WEEK 29-32 ﺍﻟﻘ ﺎ ﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎ WEEK 29-32 The brain contains almost 98% of the body’s neural tissue. Average weight of a new-born human brain ~ 350-400 g, and adult human brain ~1300-1400 g. ﺪﺍ ﻟﻘﺎ cerebral ﺩﺭ ... It is constituted of nerve cells, glial cells, blood vessels and cerebrospinal fluid. ﺩﺭ ﻋﺒ ﺪﺍ ﺍﻟﻘ ﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ Dr Abdel Ennaceur )(Feb. 2024 ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ The surface anatomy includes cerebellum, and brainstem. ﺻﺮ ﺍﻟﻨﺎ 1 The brain is the central organ of the nervous system, ﺻﺮ MPharm Programme ﺍ ﻟﻘﺎ 2/12/2024 ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ Introduction ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ 2/12/2024 ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ &\ ﻋﺒﺪ The CNS underlie all the activity of the nervous system forms a communication network coordinates all the systems of the body and enables them to function. integrates the information that it receives from all parts of the body. ﻋﺒﺪ ﻟﻘﺎ ﺩﺭ ﺍﻟﻘﺎ .. .... .... .... ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺩﺭ ﺩﺭ .... .... . ﺍﻟﻨﺎ &\ .... ﻋﺒﺪ .... . ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻘﺎ ﻋﺒﺪ ... ﺍﻟﻘﺎ ﺩﺭ .... ﺻﺮ ﻨﺎ .... ﺭ ﺍﻟ WEEK 29-32 ﺩﺭ ﺻﺮ .... ﺍﻟﻨﺎ .... ﻋﺒ .... . . ﻋﺒ ﻋﺒ ﺪﺍ ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ Slide 4 of 76 ﺻﺮ ﺍﻟﻨﺎ £ﻋﺒ .. ... ... . ... ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨ ﺪﺍ ﻟﻘﺎ ﺩﺭ . ... ... . ... ﺪﺍ ﻟﻘﺎ .. ... . ... ... ... ﺎﺻ ﺮ$ ... . ... ﺍﻟﻨﺎ ﺻﺮ ... ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ... ... ... ﻋﺒ .. ﺮ$ ﺍﻟﻘ .. ﺪ ﺍﻟﻘ ... ﻟﻘﺎ ... ... ... ... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺩﺭ Ganglion (ganglia, plural): collection of neuron cell bodies in the PNS (except, basal ganglia). ﺪﺍ ﺩﺭ . ﺍﻟﻨﺎ ﺻﺮ . ... ﺍﻟﻨﺎ .. . ... ﻟﻘﺎ ﺻﺮ Nucleus (nuclei, plural): collection of neuron cell bodies in the CNS. ﺩﺭ ﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ﺩﺭ ﺮ$ ﻋﺒ ... ﺩﺭ ﻋﺒ ﺍﻟﻨﺎ ﺪﺍ ﻟﻘﺎ ﺻﺮ ... ... ﺪ ﺍﻟﻘ . ... . ... ﺎ ﺩﺭ ... Tract a group of axons bundled together in the CNS. ﻋﺒﺪ ... ... . ... . ... ... ﺍﻟﻨﺎ ﺻﺮ ... ﻋﺒﺪ ﺍﻟﻨﺎ ﺍﻟﻘ ﺻﺮ ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... ... ﻋﺒﺪ .. Nerve is a group of axons bundled together in the PNS (Cranial nerves; Spinal nerves). Nerve fascicle, or fasciculus is a bundle of funiculi. A funiculus is a bundle of axons. ﺻﺮ ... ... ﻋﺒﺪ ... ﺍ ﻟﻘﺎ ﺩﺭ ... ... 1 ﺍﻟﻘ ... ﻨﺎﺻ ﺍﻟ ﻋﺒ ﺪﺍ .. ﺍ ﻟﻘﺎ ﺩﺭ .. ... ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ . ... ... ... ﺍﻟﻨﺎ ﺻﺮ ... ... ... ﺻﺮ ... ﺍﻟﻨﺎ ﺻﺮ ... ﻋﺒﺪ ... ﻋﺒﺪ .. ﻋﺒﺪ ﺍ ﻟﻘﺎ ... ﺍ ﻟﻘﺎ ... ... ﺍﻟﻘ ﺍﻟﻨﺎ ﺩﺭ ... ... ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ . ... WEEK ﻋﺒﺪ Terminology - Neurons Slide 3 of 76 ﺍ ﻟﻘﺎ PHA 112 – CNS : Brain Structures and Functions PHA 112 – CNS : Brain Structures and Functions 2 ... Neurons are the primary constituents of the nervous system. receive messages from other neurons through dendrites dendrites carry message to the neuron's cell body. axon carries outgoing messages. ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ White and Gray matter ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ 2/12/2024 ﺩﺭ ﺍﻟﻨﺎ ﺍﻟﻨﺎ ﻋﺒﺪ ﻟﻘﺎ ﺩﺭ ﺍﻟﻘﺎ ﺩﺭ .. .... .... .... ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺩﺭ ﺩﺭ .... .... . ﺍﻟﻨﺎ &\ .... ﻋﺒﺪ .... . ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻘﺎ ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺻﺮ .... ﺍﻟﻨﺎ .... ﺩﺭ .... ﺻﺮ ﻨﺎ .... ﺭ ﺍﻟ WEEK 29-32 ﺩﺭ ﻋﺒ ﻋﺒ ﺪﺍ ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ Slide 6 of 76 ﺻﺮ ﺍﻟﻨﺎ £ﻋﺒ .. ... ... . ... ﺪﺍ . ﻋﺒ .. ... . ... ﺪﺍ ﻟﻘﺎ . ... ... . ... ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ... ... ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... ... ... ... ... ﻟﻘﺎ ﺩﺭ ﺻﺮ .. ﻋﺒ . ﺍﻟﻨﺎ ﺻﺮ ... ... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ... ... ﺪ ﺍﻟﻘ ﺪﺍ ﻟﻘﺎ . ... ﺩﺭ ... ﺍﻟﻨﺎ . ... . ... ﺎ ﺩﺭ ... ... ﻋﺒ ﺍﻟﻨﺎ ﻟﻘﺎ .. ﺻﺮ ﺩﺭ . ... ﻋﺒﺪ ﺍﻟﻘ ﺻﺮ ﺎ ﺩﺭ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍﻟﻘ ﺻﺮ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ﺮ$ ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ . ... ﻋﺒ ... ... ... ﺪ ﺍﻟﻘ . ... ﺮ$ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ .. ﺍﻟﻨﺎ ﺻﺮ . ... ﺍﻟﻨﺎ ﺻﺮ ... ... ﺎ ﺩﺭ ﻋﺒﺪ ... ... ... ... ﺍ ﻟﻘﺎ ﺩﺭ .. ﺎﺻ ... ... ... ... ﻋﺒﺪ .. ... ﺍﻟﻨﺎ ... ﺮ$ .. ﺍ ﻟﻘﺎ ﺩﺭ ﻨﺎﺻ ﺍﻟ ﻋﺒ ﺪﺍ ﺻﺮ ... ... ... ﺻﺮ ... ... ﺎ ﺩﺭ . ... ... ... ... ﻋﺒﺪ ... ﺻﺮ ... ﻋﺒﺪ ... ﺍ ﻟﻘﺎ ﻋﺒﺪ ﺍ ﻟﻘﺎ ... ... ﺩﺭ .. ﺍﻟﻘ ﺍﻟﻨﺎ ... ﺍﻟﻨﺎ ﺎ ﺩﺭ ... ... ... . ... ﺻﺮ ﺍﻟﻨﺎ The main nerve tracts in the CNS are of 3 types: Association fibers: connect cortical areas within the same hemisphere. Commissural fibers: connect corresponding cortical areas in the two hemispheres. They cross from one cerebral hemisphere to the other through bridges called commissures. Projection fibers: connect the cerebral cortex with the corpus striatum, diencephalon, brainstem and the spinal cord. PHA 112 – CNS : Brain Structures and Functions 3 ﺍﻟﻨﺎ Nerve tracts Slide 5 of 76 ﻋﺒﺪ PHA 112 – CNS : Brain Structures and Functions ﺻﺮ Both the spinal cord and the brain consist of: White matter = bundles of axons each coated with a sheath of myelin Gray matter = masses of cell bodies and dendrites - each covered with synapses ﺍ ﻟﻘﺎ ﺻﺮ ﺻﺮ &\ ﻋﺒﺪ A myelin sheath, made up of glial cells, cover some neurons. It increases neuron efficiency and provides insulation. Multiple sclerosis: CNS demyelinating disease. Guillain-Barre syndrome demyelinating disease in the PNS. ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ 2/12/2024 WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ Terminology - ascending vs. descending ﻋﺒﺪ Nerves are categorized into 3 groups based on the direction of the signals: ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ &\ Afferent nerves: signals from sensory neurons to the CNS. ﺍﻟﻨﺎ ﺍ ﻟﻘﺎ ﻟﻘﺎ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ... ... Efferent nerves: signals from the CNS along motor neurons to their target muscles and glands. ﺍﻟﻘﺎ ﺩﺭ .. .... .... .... ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺩﺭ ﺩﺭ .... .... . ﺍﻟﻨﺎ &\ .... . ﺻﺮ ﻋﺒﺪ .... ﻋﺒﺪ ﺍﻟﻘﺎ ﺍﻟﻘ ﻋﺒﺪ ... ﺍﻟﻘﺎ .... ﺻﺮ ﻨﺎ .... ﺭ ﺍﻟ WEEK 29-32 ﺩﺭ ﺩﺭ .... . ﺻﺮ .... ﺍﻟﻨﺎ .... ﻋﺒ ﺪﺍ ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ Slide 8 of 76 ﺻﺮ ﺍﻟﻨﺎ £ﻋﺒ ﺪﺍ ﻟﻘﺎ ﻋﺒ ﺪﺍ . .. ... ﻋﺒ ﺪﺍ ﻟﻘﺎ . ... ... . ... ﻟﻘﺎ .. ... ... . ... ... ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... ... ﺩﺭ . ... ... ... ﻟﻘﺎ ﺩﺭ ... ... ... ... ﺍﻟﻨﺎ ﺻﺮ ... ﻋﺒ . ﺍﻟﻨﺎ ﺻﺮ . ... ﺪﺍ ﻟﻘﺎ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ .. ﺍﻟﻨﺎ ﺩﺭ . ... ﺻﺮ .. ﻋﺒ ... ﺩﺭ Descending or Efferent pathway is made of one or a series of neurons projecting from the brain toward the periphery. ﻋﺒﺪ ... ... ﺪ ﺍﻟﻘ . ... . ... ﺍﻟﻨﺎ ﺍﻟﻘ ﺻﺮ ﺎ ﺩﺭ ﻋﺒﺪ Ascending or Afferent pathway is made of one or a series of neurons projecting from the periphery toward the brain. ﺍﻟﻨﺎ ﻋﺒ . ... ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... ... ﺍﻟﻘ ﺻﺮ ... ... ﺎ ﺩﺭ ﻋﺒﺪ ﺩﺭ ﺍﻟﻨ ﺎﺻ ﺮ$ . ... ... ... ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ .. ﺪ ﺍﻟﻘ . ... ﺮ$ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ... ... ﺍﻟﻨﺎ ﺎ ﺩﺭ ﻋﺒﺪ ... ... ﺻﺮ ... ﺍ ﻟﻘﺎ ﺩﺭ .. ﺮ$ ... ... ﻋﺒﺪ ﺍﻟﻨﺎ ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒ ﺪﺍ .. ﺍ ﻟﻘﺎ ﺩﺭ .. ... ﺻﺮ ... ... ﺍﻟﻨﺎ ﺻﺮ ... ﺍﻟﻨﺎ ﺻﺮ ... ... ... ﻋﺒﺪ ... ﻋﺒﺪ . ... ... ... ... ﺍ ﻟﻘﺎ .. ﺍﻟﻘ ﻋﺒﺪ ... ﺩﺭ ﺍﻟﻨﺎ ... ... ... ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ . ... Terminology - Ascending vs. Descending PHA 112 – CNS : Brain Structures and Functions 4 Slide 7 of 76 ﺍ ﻟﻘﺎ PHA 112 – CNS : Brain Structures and Functions ﺻﺮ Mixed nerves contain both afferent and efferent axons, and thus conduct both incoming sensory information and outgoing muscle commands in the same bundle. Example: spinal nerves ... ... ... . ... ﺍﻟﻨﺎ ﺻﺮ ... The dorsal horn is the first point of synapse of sensory neurons. Located inside the spinal cord. Slide 9 of 76 ﺻﺮ ﻋﺒﺪ ﺻﺮ ﻨﺎ .... ﺻﺮ ﺍﻟﻨﺎ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘﺎ .... .... .... ... ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻨﺎ .... . .... ... ﺩﺭ ﺍﻟﻘﺎ .... .... ﺻﺮ ﺍﻟﻨﺎ .... . . ﺩﺭ ... ﺩﺭ £ﻋﺒ ﺎﺻ ﺍﻟﻨ ... . ... ﻋﺒ ﺮ$ ﻋﺒﺪ ... ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ ﺮ$ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ . ... ... ... ﺍﻟﻨﺎ ﺎﺻ ﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ ... ... ﺻﺮ .. ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ ﺪ ﺍﻟﻘ ﺪﺍ ﻟﻘﺎ ﺻﺮ . ... ﺍﻟﻨﺎ .. ... ... ﻟﻘﺎ ﺪﺍ ﻋﺒ . ... ... . ... ... ... .. ... ... . ... . ... ... ... ... ... .. ... ﺻﺮ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ Cranial and Spinal Nerves ﺻﺮ ﻋﺒﺪ .... . .. ... . ... ... ... ... . . ... ... . ... ... ... . ﻋﺒﺪ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ .... ﻋﺒ ... ... ... ... ﺍﻟﻨﺎ .. . ... ... ... ... ... ﺍ ﻟﻘﺎ ﺍﻟﻨﺎ ﺻﺮ &\ ﻋﺒﺪ ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ... ... ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒﺪ ﺩﺭ ﺍ ﻟﻘﺎ ﺮ$ ﺍ ﻟﻘﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ .... . ... ... .. ... ... ... .... ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘ ﺩﺭ ﺭ ﺍﻟ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﻋﺒﺪ ﺍﻟﻨﺎ ﺻﺮ PHA 112 – CNS : Brain Structures and Functions .. ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺩﺭ &\ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ WEEK 29-32 ﺍﻟﻘ ﺎ ﺩﺭ ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻘﺎ PHA 112 – CNS : Brain Structures and Functions ... ﺩﺭ ... ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ Cranial nerves innervate parts of the head, and connect directly to the brain (especially to the brainstem). WEEK 29-32 Slide 10 of 76 ﺩﺭ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ They are typically assigned Roman numerals from 1 to 12 and descriptive names. ﺻﺮ ﺍﻟﻨﺎ 5 The dorsal root ganglia (plural of ganglion) contain the cell bodies of sensory neurons. Located outside the spinal cord. ﺻﺮ Dorsal root ganglion and dorsal horn ﺍ ﻟﻘﺎ 2/12/2024 $ﺮ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ. ﺻ.. ﺮ. ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ.....ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ. ﻨ ﺻﺮ.. ﻟ.... ﺭﺍ.... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ.... ﻘﺎﺩ.... ﺩ ﺩﺭ ﻋﺒﺪ..... ﺪ ﺍﻟ ﺍﻟﻘﺎ........ ﺍﻟﻘﺎ £...... ﻋﺒ ﺪ.. ﺒ. ﻋﺒﺪ ﻋ........ ﺻﺮ.... ﺻﺮ. ﺎ..... ﻨ ﺮ.... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ..... ﺭ ﺍﻟ ﻘﺎﺩ...... ﺍﻟﻨﺎ ﺩﺭ.... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ..... ﻟ ﻋﺒ ﺎ. ﻋﺒﺪ ﺪﺍ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ... ﻋﺒ. ﻋﺒﺪ. ﺮ......... ﻨﺎﺻ ﺻﺮ.... ﺻﺮ. ﻟ ﺎ ﺍ. ﺍﻟﻨ.... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ. ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ.... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ.... ﻋﺒﺪ.... ﺻﺮ ﺻﺮ.... ﺍﻟﻨﺎ ﺍﻟﻨﺎ.... ﻋﺒﺪ ﺩﺭ..ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ.... ﻋﺒﺪ ﻋﺒﺪ........ ﺻﺮ.... ﺍﻟﻨﺎ.. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ... ﻋﺒ ﺎ 2/12/2024 WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ Spinal & Cranial Nerves ﻋﺒﺪ Spinal nerves: there are 31 pairs in humans. ﺍ ﻟﻘﺎ ﻟﻘﺎ ﺩﺭ ﻋﺒﺪ ﺩﺭ......... ﺍﻟﻨﺎ ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ \& arise from the spinal cord supply the rest of the body connect CNS to the periphery ﺍﻟﻘﺎ ﺩﺭ...... ﻨﺎﺻ ﺍﻟ.... $ﺮ.... ﻋﺒﺪ... ﺍﻟﻘﺎ......... ﺩﺭ ﺍﻟﻨﺎ..... ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ..... ﺻﺮ \&.... ﻋﺒﺪ ﺍﻟﻘ ﻋﺒﺪ... ﺭ ﺍﻟ ﺍﻟﻘﺎ ﺍﻟﻨﺎ.... ﺩﺭ.... ﺻﺮ ﻨﺎ.............. ﺪﺍ ﻟﻘﺎ ﺻﺮ ﺩﺭ ﻋﺒ.... ﺍﻟﻨﺎ ﺻﺮ...... ﻟﻘﺎ ﺩﺭ......... ﺍﻟﻨﺎ ﻋﺒ ﺻﺮ....... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ..... ﺍﻟﻨﺎ.... ﺻﺮ... ﺪﺍ ﻟﻘﺎ ﻋﺒﺪ ﺩﺭ...... ﻋﺒ.... ﺍﻟﻨﺎ ﺍﻟﻘ............ ﺍﻟﻨﺎ ﻋﺒ£ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﻋﺒﺪ ﺍﻟﻨ ﺎﺻ ﺍﻟﻘﺎ $ﺮ ﺻﺮ ﺪ ﺍﻟﻘ. ﺻﺮ ﺎ ﺩﺭ Dendrites: treelike branches extending from the soma of a neuron. receive incoming signals from other neurons. make up most of the receptive zone of a neuron. have membrane receptors.... ﻋﺒ..... ﺎ ﺩﺭ... ﻋﺒﺪ...... ﺍﻟﻨﺎ....... ﺻﺮ...... ﺍﻟﻘ ﺍﻟﻨﺎ Cell body (soma) is the factory of the neuron. produces all the proteins for the dendrites, axons and synaptic terminals contains organelles: mitochondria, golgi apparatus, endoplasmic reticulum, secretory granules, ribosomes and polysomes..... ﺪ ﺍﻟﻘ......... ﺎ ﺩﺭ...... ﺎ ﺩﺭ ﺻﺮ A neuron comprises a cell body, an axon and dendrites. ﻋﺒﺪ.. ﺍﻟﻨﺎ ﻋﺒﺪ......... ﺻﺮ... ﺍ ﻟﻘﺎ ﺩﺭ... ﺍﻟﻨﺎ ﺻﺮ Neuron - Soma, dendrites & Axons ﻋﺒﺪ WEEK 29-32 ﺍﻟﻘ ﺎ ﺩﺭ PHA 112 – CNS : Brain Structures and Functions...... ﻋﺒﺪ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨ......... ﺍﻟﻨﺎ... ﺍﻟﻘ ﻋﺒﺪ..... ﺻﺮ..... ﺍ ﻟﻘﺎ ﺩﺭ ﺎﺻ.. ﺍﻟﻨﺎ......... ﻋﺒﺪ...... ﺎ ﺩﺭ Slide 11 of 76 ﺻﺮ ﺍﻟﻨﺎ ﺻﺮ ﺍ ﻟﻘﺎ... ﺍﻟﻨﺎ ﺻﺮ Each spinal nerve branches into two roots: anterior or ventral relays sensory information posterior or dorsal root relays motor information. $ﺮ................. ﺩﺭ ﻋﺒ ﺪﺍ... ﻋﺒﺪ... ﺍﻟﻨﺎ ﺻﺮ Letter-number designations based on the vertebra through which they connect to the spinal column. ﺪﺍ ﻟﻘﺎ..... ﺩﺭ ﻋﺒ... ﺍﻟﻨﺎ... ﺻﺮ...... ﻋﺒ PHA 112 – CNS : Brain Structures and Functions ﺪﺍ ﻟﻘﺎ... ﺩﺭ... Slide 12 of 76 ﺪﺍ Axon: is a projection of a nerve cell, or neuron. conducts action potentials away from the neuron cell body. has knob-like swellings at the very end called synaptic knobs or end buttons. Neurotransmitters are released from the axon terminal buttons. ﻋﺒ 6 ... . ... ... ... ﺍﻟﻨﺎ ﺻﺮ Slide 13 of 76 ﺻﺮ ﻨﺎ .... ... Synapse site of transmission of electric nerve impulses between two nerve cells or between a neuron and a gland or a muscle cell. ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘﺎ .... .... .... ... ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻨﺎ .... .... . ﺻﺮ ... ﺩﺭ ﺍﻟﻘﺎ .... .... ﺻﺮ ﺍﻟﻨﺎ .... . . ﺩﺭ ... ﺩﺭ £ﻋﺒ ﺎﺻ ﺍﻟﻨ ... . ... ﻋﺒ ﺮ$ ﻋﺒﺪ ... ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ ﺮ$ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ . ... ... ... ﺍﻟﻨﺎ ﺎﺻ ﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ ... ... ﺻﺮ .. ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ ﺪ ﺍﻟﻘ ﺪﺍ ﻟﻘﺎ ﺻﺮ . ... ﺍﻟﻨﺎ .. ... ... ﻟﻘﺎ ﺪﺍ ﻋﺒ . ... ... . ... ... ... .. ... ... . ... . ... ... ... ... ... .. ... ﺻﺮ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ Neuron & Dendrites ﺻﺮ ﻋﺒﺪ .... . .. ... . ... ... ... ... . . ... ... . ... ... ... . ﻋﺒﺪ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ .... ﻋﺒ ... ... ... ... ﺍﻟﻨﺎ .. . ... ... ... ... ... ﺍ ﻟﻘﺎ ﺍﻟﻨﺎ ﺻﺮ &\ ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ... ... ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒﺪ ﺩﺭ ﺍ ﻟﻘﺎ ﺮ$ ﺍ ﻟﻘﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ .... . ... ... .. ... ... ... .... ﻋﺒﺪ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘ ﺩﺭ ﺭ ﺍﻟ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﻋﺒﺪ ﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ PHA 112 – CNS : Brain Structures and Functions .. Neuron – Terminal buttons & Synapses ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺩﺭ &\ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ WEEK 29-32 ﻋﺒﺪ ﺍﻟﻘﺎ PHA 112 – CNS : Brain Structures and Functions ... ﺩﺭ ... ﺍﻟﻘ 1 WEEK 29-32 Slide 14 of 76 ﺩﺭ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ Neurotransmitters carry the signal across the synapse. released into the synaptic gap. bind and activate receptors on the other nerve cells. ﺻﺮ ﺍﻟﻨﺎ 7 WEEK ﺻﺮ Terminal buttons located at the end of the neuron responsible for sending the signal to other neurons. contain vesicles holding the neurotransmitters terminal buttons convert electrical impulses into chemical signals ﺍ ﻟﻘﺎ 2/12/2024 ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ Neuron – Axonal transport ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ 2/12/2024 ﺻﺮ &\ ﻋﺒﺪ Kinesin transport substances from cell body to axon terminal, toward the plus end of the microtubule (anterograde transport). ﺍﻟﻘﺎ ﺩﺭ .. .... .... .... ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺩﺭ ﺩﺭ .... .... . ﺍﻟﻨﺎ &\ .... ﻋﺒﺪ .... . ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻘﺎ ﻋﺒﺪ ... ﺭ ﺍﻟ WEEK 29-32 ﺩﺭ ﺍﻟﻘﺎ .... .... ﺩﺭ .... ﺻﺮ ﻨﺎ .... . .... ﺍﻟﻨﺎ ﺻﺮ . ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ Slide 16 of 76 ﺻﺮ ﺍﻟﻨﺎ £ﻋﺒ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﻋﺒ ﺪﺍ ﻟﻘﺎ . ... ... . ... ... ... .. ... ﻋﺒ ﺪﺍ ... ... ﻟﻘﺎ ﺩﺭ . ... ... ... ... ﺩﺭ . ﺍﻟﻨﺎ ﺻﺮ ... ... ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻨﺎ . ... ﻋﺒ .. . ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺪﺍ ﻟﻘﺎ )Neurofibrillary tangles (NFTs They consist of insoluble twisted fibres. They form inside the neuron and these are composed of abnormally processed tau. They primarily consist of a protein called tau, which forms part of a structure called a microtubule. ﺻﺮ ﺻﺮ ... ﻋﺒ . ... ﺩﺭ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻨﺎ In AD, however, the tau protein is abnormal and the microtubule structures collapse. ﺎ ﺩﺭ .. ... ... . ... ﺍﻟﻨﺎ ﺻﺮ .. ﺪ ﺍﻟﻘ ﺻﺮ ﺎ ﺩﺭ . ... ﻋﺒﺪ ﺍﻟﻨﺎ ... Microtubules are like a train tracks involved in transport of nutrients, proteins and other important substances from the neuron cell body to other parts of the nerve cell. ﺻﺮ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ﺮ$ ... . ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ... ... ... ﻋﺒ ... ... ﺮ$ ﺍﻟﻘ .. ﺪ ﺍﻟﻘ . ... . ... ... ﺍﻟﻨﺎ ﺻﺮ ... ... ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ... ... ﺍﻟﻨﺎ ﺎ ﺩﺭ ﻋﺒﺪ ... ... ﺻﺮ ... ﺍ ﻟﻘﺎ ﺩﺭ .. ﺮ$ ... ... ﻋﺒﺪ ﺍﻟﻨﺎ ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒ ﺪﺍ ﺍ ﻟﻘﺎ ﺩﺭ .. ﺍﻟﻨﺎ ﺻﺮ .. ... ﺻﺮ ... ... ﺎ ﺩﺭ . ... ... ... ﻋﺒﺪ ... ... ... ﻋﺒﺪ ... ﺍﻟﻨﺎ ﺻﺮ ... ﺍ ﻟﻘﺎ ... ﺍ ﻟﻘﺎ .. ﻋﺒﺪ ﻟﻘﺎ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ﺩﺭ ... ... ﺍﻟﻘ ﺍﻟﻨﺎ ﺍﻟﻨﺎ ... ... ... ﺍﻟﻨﺎ ﺻﺮ ... . ... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ Neuron – Axonal transport PHA 112 – CNS : Brain Structures and Functions 8 ﺎ ﺩﺭ PHA 112 – CNS : Brain Structures and Functions Slide 15 of 76 ﺍ ﻟﻘﺎ ﺻﺮ Dynein transport substances from the axon terminal to the cell body, toward the minus end of the microtubule (retrograde transport). ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ WEEK 29-32 ﺍ ﻟﻘﺎ ﺩﺭ Synapse ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ 2/12/2024 ﺍﻟﻨﺎ ﺩﺭ .. .... .... .... ﻋﺒﺪ ... ﺍﻟﻘﺎ .... . ﺩﺭ ﺩﺭ .... .... . ﺍﻟﻨﺎ &\ .... ﻋﺒﺪ .... . ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻘﺎ ... ﺭ ﺍﻟ WEEK 29-32 ﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎ .... .... ﺩﺭ .... ﺻﺮ ﻨﺎ .... . .... ﺍﻟﻨﺎ ﺻﺮ . ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ Slide 18 of 76 ﺻﺮ ﺍﻟﻨﺎ £ﻋﺒ .. ... ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ . ... ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ﺮ$ ... . ... . ... ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ... .. ... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ . ... ... ... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ .. ﻋﺒ ﺮ$ ﺍﻟﻘ ... ... ﺪ ﺍﻟﻘ . ... ﺪﺍ ... ... ﻟﻘﺎ ﺩﺭ ﺎ ﺩﺭ ﺍﻟﻨ ﺎﺻ ... ... ﺎ ﺩﺭ ... ... ... ﻨﺎﺻ ﺍﻟ ﺮ$ ... ... ... . ﺍﻟﻨﺎ . ... ﺍﻟﻨﺎ ﺻﺮ ... ... ﺍﻟﻨﺎ ﺻﺮ ... ﻋﺒ . ... ﻋﺒ .. ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ . ... Interneurons connect various within the brain and spinal cord. ﺩﺭ neurons ﺍﻟﻨﺎ ﺪﺍ ﻟﻘﺎ Motor neurons (motoneurons) carry signals from the CNS to the outer parts (muscles, skin, glands) of the body. ﺻﺮ . ... ﺪ ﺍﻟﻘ . ... ﺎ ﺩﺭ ... ﺍﻟﻨﺎ ﺻﺮ ﺩﺭ ﻋﺒﺪ ﺍﻟﻘ ﺍﻟﻨﺎ . ... ﺍﻟﻨﺎ ... ﺻﺮ ... ... Sensory neurons carry signals from the outer parts of the body (periphery) into the CNS. ﺎ ﺩﺭ ﺻﺮ ... ... ... ... ﻋﺒﺪ .. ﻋﺒﺪ ﺍﻟﻨﺎ ... ﻋﺒﺪ .. ... ﺍ ﻟﻘﺎ ﺩﺭ ... ﺍﻟﻘ There are 3 different types of neurons, each with a different function: ﺻﺮ ﻋﺒ ﺪﺍ .. ﺍﻟﻘﺎ ﻟﻘﺎ ﺩﺭ ﺍ ﻟﻘﺎ ﺩﺭ ... ... ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ ... ﺍﻟﻨﺎ ﺻﺮ ... ﺻﺮ ... ﺍﻟﻨﺎ ﺻﺮ . ... ... ... ... ﻋﺒﺪ .. ﻋﺒﺪ ﻋﺒﺪ ... ﺍ ﻟﻘﺎ ... ... ﺍﻟﻘ ﺍ ﻟﻘﺎ ﻋﺒﺪ ﺩﺭ ... ... ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ... . ... ﺍﻟﻨﺎ ﺻﺮ Slide 17 of 76 ﻋﺒﺪ Types of neurons ﺎ ﺩﺭ PHA 112 – CNS : Brain Structures and Functions PHA 112 – CNS : Brain Structures and Functions 9 ... Neurotransmitter receptors: o integral membrane glycoproteins. o drugs bind receptor, reproduce (agonists) or block (antagonist) action of neurotransmitter. o receptor subtypes identified for most neurotransmitters. ﺍ ﻟﻘﺎ .. ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ &\ ﻋﺒﺪ The synapse is a small gap separating neurons. It consists of: a presynaptic ending a postsynaptic neuron a synaptic cleft or space $ﺮ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ. ﺻ.. ﺮ. ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ.....ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ. ﻨ ﺻﺮ.. ﻟ.... ﺭﺍ.... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ.... ﻘﺎﺩ.... ﺩ ﺩﺭ ﻋﺒﺪ..... ﺪ ﺍﻟ ﺍﻟﻘﺎ........ ﺍﻟﻘﺎ £...... ﻋﺒ ﺪ.. ﺒ. ﻋﺒﺪ ﻋ........ ﺻﺮ.... ﺻﺮ. ﺎ..... ﻨ ﺮ.... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ..... ﺭ ﺍﻟ ﻘﺎﺩ...... ﺍﻟﻨﺎ ﺩﺭ.... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ..... ﻟ ﻋﺒ ﺎ. ﻋﺒﺪ ﺪﺍ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ... ﻋﺒ. ﻋﺒﺪ. ﺮ......... ﻨﺎﺻ ﺻﺮ.... ﺻﺮ. ﻟ ﺎ ﺍ. ﺍﻟﻨ.... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ. ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ.... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ.... ﻋﺒﺪ.... ﺻﺮ ﺻﺮ.... ﺍﻟﻨﺎ ﺍﻟﻨﺎ.... ﻋﺒﺪ ﺩﺭ..ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ.... ﻋﺒﺪ ﻋﺒﺪ........ ﺻﺮ.... ﺍﻟﻨﺎ.. ﺩﺭ ﺍﻟﻘﺎ ﺪ Types of neurons ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ WEEK 29-32 2/12/2024 ﻋﺒﺪ Neural transmission can be slow as 0.5 meters/sec or fast as 120 meters/sec (431km/hr). \& ﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎ ﺩﺭ...... ﻨﺎﺻ ﺍﻟ.... $ﺮ.... ﻋﺒﺪ... ﺍﻟﻘﺎ......... ﺩﺭ ﺍﻟﻨﺎ..... ﺩﺭ..... ﺻﺮ.... ﻋﺒﺪ ﻋﺒﺪ... ﺍﻟﻘﺎ........ ﻟﻘﺎ ﺩﺭ.............. ﻋﺒ£ ﺪﺍ ﻟﻘﺎ ﺩﺭ...... ﺍﻟﻨﺎ ﺍﻟﻘ ﺍﻟﻨ ﺎﺻ ﺻﺮ...... ﻋﺒ ﺍﻟﻨﺎ ﺍﻟﻘ.... ﺻﺮ ﺪ ﺍﻟﻘ.... ﺎ ﺩﺭ... ﻋﺒﺪ ﺎ ﺩﺭ ﺭ ﺍﻟ $ﺮ....... ﻋﺒ.... ﺍﻟﻨﺎ... ﺍﻟﻘ ﺍﻟﻨﺎ ﺻﺮ ﻨﺎ ﻋﺒﺪ ﺪ ﺍﻟﻘ......... ﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ.. ﺻﺮ ﺻﺮ Sensory receptors... ﺎ ﺩﺭ......... \& ﺍﻟﻨ............ ﻋﺒﺪ... ﻋﺒﺪ............ ﺍ ﻟﻘﺎ ﺩﺭ...... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ ﺎﺻ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ PHA 112 – CNS : Brain Structures and Functions Sensory receptors - May be external (cutaneous), internal (visceral/somatic) or both - Type and density vary according to location - Contribute to variations in sensitivity ﺻﺮ ﺍﻟﻘﺎ $ﺮ.. ﺍﻟﻨﺎ..... ﺻﺮ... ﻋﺒﺪ WEEK 29-32 ﻋﺒ ﺪﺍ ﺻﺮ The thickness of a nerve fiber is correlated to the speed with which information travels in it -- the thicker the nerve fiber, the faster information travels in it.......... ﻋﺒﺪ.. ﺍﻟﻘ ﻋﺒﺪ.... ﺩﺭ.......... ﺪﺍ ﻟﻘﺎ ﺻﺮ ﺩﺭ ﻋﺒ..... ﺪﺍ ﻟﻘﺎ ﻋﺒ... ﺍﻟﻨﺎ... ﺻﺮ...... ﺩﺭ.... ﺍﻟﻨﺎ ﺻﺮ...... ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ......... ﻋﺒ ﺍﻟﻨﺎ....... ﻋﺒ ﺪﺍ..... ﺍﻟﻨﺎ ﺻﺮ.... ﺪﺍ ﻟﻘﺎ ﺻﺮ PHA 112 – CNS : Brain Structures and Functions ﺪﺍ ﻟﻘﺎ... ﺩﺭ... Slide 20 of 76... ﺩﺭ ﻋﺒﺪ Sensory receptors are - either specialized endings of afferent neurons or separate cells (e.g. hair cells in the inner ear or taste receptor cells). - detect and respond to physical and/or chemical stimuli. - highly sensitive to specific inputs or sensory modalities, such as movement, odor chemicals or visible light photons. - convert one form of energy (e.g. heat, pressure, chemical) into another form (e.g. electrical energy or depolarization) ﺍﻟﻨﺎ ﺩﺭ ﻟﻘﺎ ﺩﺭ... ﺍ ﻟﻘﺎ.......... ﻋﺒﺪ... ﺍ ﻟﻘﺎ... ﺩﺭ...... ﺎ ﺩﺭ ﺍ ﻟﻘﺎ ﺻﺮ ﺍﻟﻨﺎ ﺩﺭ ﺍﻟﻨﺎ ﺍﻟﻨﺎ......... ﺍﻟﻨﺎ ﺻﺮ....... ﺍﻟﻨﺎ ﺻﺮ Slide 19 of 76 ﺻﺮ Primary afferent axons transmit info about touch and pain to the spinal cord and brain. - A-, A- and A- nerve fibers → myelinated. - C-nerve fibers → unmyelinated. - A- nerve fibers (motor neurons)→myelinated. ﻋﺒ 10 $ﺮ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ. ﺻ.. ﺮ. ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ.....ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ. ﻨ ﺻﺮ.. ﻟ.... ﺭﺍ.... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ.... ﻘﺎﺩ.... ﺩ ﺩﺭ ﻋﺒﺪ..... ﺪ ﺍﻟ ﺍﻟﻘﺎ........ ﺍﻟﻘﺎ £...... ﻋﺒ ﺪ.. ﺒ. ﻋﺒﺪ ﻋ........ ﺻﺮ.... ﺻﺮ. ﺎ..... ﻨ ﺮ.... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ..... ﺭ ﺍﻟ ﻘﺎﺩ...... ﺍﻟﻨﺎ ﺩﺭ.... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ..... ﻟ ﻋﺒ ﺎ. ﻋﺒﺪ ﺪﺍ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘ..ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ... ﻋﺒ. ﻋﺒﺪ. ﺮ......... ﻨﺎﺻ ﺻﺮ.... ﺻﺮ. ﻟ ﺎ ﺍ. ﺍﻟﻨ.... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ. ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ.... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ.... ﻋﺒﺪ.... ﺻﺮ ﺻﺮ.... ﺍﻟﻨﺎ ﺍﻟﻨﺎ.... ﻋﺒﺪ ﺩﺭ..ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ.... ﻋﺒﺪ ﻋﺒﺪ........ ﺻﺮ.... ﺍﻟﻨﺎ.. ﺩﺭ ﺍﻟﻘﺎ ﺪ Types of sensory receptors ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭﺪ... ﻋﺒ ﺎ ﺍﻟﻨﺎ ﺻﺮ Sensory receptors are: Photoreceptors: to visible wavelengths of light Mechanoreceptors: mechanical changes in the environment such as movement, tension, and pressure (e.g. stretch receptors in skeletal muscle; baroreceptors sensitive to changes). Thermoreceptors: changes in temperature Osmoreceptors: changes in osmotic pressure (e.g. detect changes in ECF osmolality). Chemoreceptors: chemical composition (e.g. O2, CO2, and chemicals linked to taste and smell) Proprioceptors: joint position sense Polymodal receptors: to more than one type of stimulus Nociceptors: damage or distortion of tissues ( “pain”) ﻋﺒﺪ WEEK 29-32 2/12/2024 \& ﻋﺒﺪ ﺍﻟﻘﺎ ﺩﺭ...... ﻨﺎﺻ ﺍﻟ.... $ﺮ.... ﻋﺒﺪ... ﺍﻟﻘﺎ..... ﺩﺭ..... ﺍﻟﻨﺎ......... ﻋﺒﺪ ﺍﻟﻘ ﻋﺒﺪ... ﺍﻟﻘﺎ........ ﺭ ﺍﻟ ﺻﺮ ﻨﺎ ﺪﺍ ﻟﻘﺎ ﺩﺭ.................. ﺍﻟﻨﺎ.. ﻋﺒ... ﺍﻟﻨﺎ ﺍﻟﻘ.... ﺻﺮ ﺎ ﺩﺭ ﺪ ﺍﻟﻘ.... ﻋﺒ£ ﺻﺮ... ﻋﺒﺪ ﺍﻟﻨﺎ There are 3 types of membrane-bound receptors: 1. Ligand-gated ion channel (LGIC) receptors: located on the cell membrane and have a channel through which ions can move inside and outside the cells (e.g. nicotinic or NMDA receptors). ﺪﺍ ﻟﻘﺎ ﺩﺭ... ﻋﺒ ﺎ ﺩﺭ...... ﺍﻟﻨﺎ... ﺻﺮ ﺍﻟﻘ.... ﺻﺮ...... ﺎ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻨ ﺎﺻ ﺻﺮ $ﺮ................. ﻋﺒﺪ ﺩﺭ ﺍﻟﻘ ﺎ ﺩﺭ ﺪ ﺍﻟﻘ...... ﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ ﺍﻟﻨ ﺍﻟﻨﺎ.. ﺻﺮ ﻋﺒﺪ............ ﺍ ﻟﻘﺎ ﺩﺭ... \& ﺎﺻ............ ﻋﺒﺪ ﺍﻟﻨﺎ...... ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ $ﺮ ﺍ ﻟﻘﺎ ﺩﺭ..... ﺻﺮ... ﻋﺒﺪ WEEK 29-32 ﻋﺒ ﺪﺍ.. ﺍﻟﻨﺎ ﺻﺮ......... ﻋﺒﺪ.. ﺍﻟﻘ PHA 112 – CNS : Brain Structures and Functions Neurotransmitters and hormone receptors ﻋﺒﺪ ﺩﺭ........... ﻋﺒ.... ﺍﻟﻨﺎ ﺻﺮ. ﺻﺮ ﺪﺍ ﻟﻘﺎ.... ﺩﺭ ﻋﺒﺪ 2.G-protein–coupled (GPCRs) receptors: act through both LGIC and also enzyme-linked pathways (e.g. muscarinic or adrenergic receptors). ﺍﻟﻨﺎ. ﺪﺍ.... ﻟﻘﺎ ﺻﺮ ﺩﺭ ﻋﺒ ﺍﻟﻨﺎ ﺻﺮ.... ﺩﺭ......... ﺍﻟﻨﺎ ﻋﺒ 3.Kinase-linked receptors: transmembrane receptors. The binding of an extracellular ligand causes enzymatic activity on the intracellular (e.g. Cytokine receptors, epidermal growth factor, platelet-derived growth factor, and fibroblast growth factors...... ﺩﺭ ﻟﻘﺎ ﺩﺭ... ﺍ ﻟﻘﺎ.......... ﻋﺒﺪ... ﺍ ﻟﻘﺎ... ﺩﺭ...... ﺎ ﺩﺭ ﺍ ﻟﻘﺎ ﺻﺮ ﺍﻟﻨﺎ ﺩﺭ ﺍﻟﻨﺎ ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ......... ﺍﻟﻨﺎ ﺻﺮ....... ﺍﻟﻨﺎ ﺻﺮ Slide 21 of 76..... ﺪﺍ ﻟﻘﺎ ﻋﺒ... ﺍﻟﻨﺎ... ﺻﺮ...... ﺩﺭ...... ﻋﺒ ﺪﺍ PHA 112 – CNS : Brain Structures and Functions ﺪﺍ ﻟﻘﺎ... ﺩﺭ... Slide 22 of 76 ﻟﻘﺎ Non membrane-bound receptors Nuclear receptors: located in the nucleus of cells. Activated when ligand molecules enter the nuclear membrane. Examples: estradiol, progesterone, testosterone, cortisol, and aldosterol, thyroid hormone. ﻋﺒ 11 Slide 23 of 76 ... ... ... . ... ﺍﻟﻨﺎ ﺻﺮ ﺻﺮ ﻋﺒﺪ ﺻﺮ ﻨﺎ .... ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘﺎ .... .... .... ... ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻨﺎ .... . .... ... ﺩﺭ ﺍﻟﻘﺎ .... .... ﺻﺮ ﺍﻟﻨﺎ .... . . ﺩﺭ ... ﺩﺭ £ﻋﺒ ﺎﺻ ﺍﻟﻨ ... . ... ﻋﺒ ﺮ$ ﻋﺒﺪ ... ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨ ﺮ$ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ . ... ... ... ﺍﻟﻨﺎ ﺎﺻ ﺍ ﻟﻘﺎ ﺩﺭ ... ﻋﺒﺪ ... ... ﺻﺮ .. ﺍﻟﻨﺎ ... ... ﺎ ﺩﺭ ﺪ ﺍﻟﻘ ﺪﺍ ﻟﻘﺎ ﺻﺮ . ... ﺍﻟﻨﺎ .. ... ... ﻟﻘﺎ ﺪﺍ ﻋﺒ . ... ... . ... ... ... .. ... ... . ... . ... ... ... ... ... .. ... ﺻﺮ .. ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ Autoreceptor ﺻﺮ ﻋﺒﺪ .... . .. ... . ... ... ... ... . . ... ... . ... ... ... . ﻋﺒﺪ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ .... ﻋﺒ ... ... ... ... ﺍﻟﻨﺎ .. . ... ... ... ... ... ﺍ ﻟﻘﺎ ﺍﻟﻨﺎ ﺻﺮ &\ ﺮ$ ﻨﺎﺻ ﺮ ﺍﻟﻘﺎﺩﺭﺍﻟ . ﺻ . . ﺮ . ﺎ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ.....ﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﻨﺎﺻ . ﻨ ﺻﺮ . . ﻟ .... ﺭﺍ .... ﺭ ﺍﻟ ﺎ ﺍﻟﻨﺎ ﺍﻟﻘ .... ﻘﺎﺩ .... ﺩ ﺩﺭ ﻋﺒﺪ . . ... ﺪ ﺍﻟ ﺍﻟﻘﺎ .... .... ﺍﻟﻘﺎ £ .. .... ﻋﺒ ﺪ . . ﺒ . ﻋﺒﺪ ﻋ .... .... ﺻﺮ .... ﺻﺮ . ﺎ .... . ﻨ ﺮ .... ﺭ ﺍﻟ ﺍﻟﻨﺎ ﻨﺎﺻ ﺻﺮ . . . . . ﺭ ﺍﻟ ﻘﺎﺩ .. .... ﺍﻟﻨﺎ ﺩﺭ .... ﺪ ﺍﻟ ﺍﻟﻘﺎ ﻘﺎﺩ ﺩﺭ .... . ﻟ ﻋﺒ ﺎ . ﻋﺒﺪ ﺪﺍ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘ ﺍﻟﻨﺎﺻﺮ.. ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﻋﺒﺪ . . . ﻋﺒ . ﻋﺒﺪ . ﺮ . .... .... ﻨﺎﺻ ﺻﺮ .... ﺻﺮ . ﻟ ﺎ ﺍ . ﺍﻟﻨ .... ﺍﻟﻨﺎ ﺭ ﻘﺎﺩ ﺩﺭ . ﺩﺭ ﺪ ﺍﻟ ﺎ ﺍﻟﻘ .... ﺍﻟﻘﺎ ﻋﺒ ﻋﺒﺪ .... ﻋﺒﺪ .... ﺻﺮ ﺻﺮ .... ﺍﻟﻨﺎ ﺍﻟﻨﺎ .... ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ..ﻋﺒﺪ ﺩﺭ .. ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺩﺭ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎ ﺍﻟﻘﺎ .... ﻋﺒﺪ ﻋﺒﺪ .... .... ﺻﺮ .... ﺍﻟﻨﺎ .. ﺩﺭ ﺍﻟﻘﺎ ﺪ ﺩﺭ ﻋﺒﺪ ﺩﺭ ... ... ... ... ... ﻨﺎﺻ ﺍﻟ ﻋﺒﺪ ﺩﺭ ﺍ ﻟﻘﺎ ﺮ$ ﺍ ﻟﻘﺎ ﺩﺭ ﺻﺮ ﺍﻟﻨﺎ .... . ... ... .. ... ... ... .... ﺍﻟﻨﺎ ﺻﺮ ﺍﻟﻘ ﺩﺭ ﺭ ﺍﻟ ﺻﺮ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﻋﺒﺪ ﺍﻟﻨﺎ ﺻﺮ PHA 112 – CNS : Brain Structures and Functions .. ﺍﻟﻘﺎ ﺍﻟﻘﺎﺩﺭﺩﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻨﺎﺻﺮ ﻋﺒﺪ ﺍﻟﻨﺎﺻﺮ ﺍﻟﻨﺎﺻﺮ toﻋﺒﺪ ﻋﺒﺪ ﺍﻟﻘﺎﺩﺭ ﺍﻟﻘﺎﺩﺭﺪ IUPHAR/BPS Guide PHARMACOLOGY ... ﻋﺒ ﺎ ﺩﺭ &\ ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ ﺍﻟﻨﺎ WEEK 29-32 ﺍﻟﻘ ﺎ ﺩﺭ ﻋﺒﺪ ﺍﻟﻘﺎ PHA 112 – CNS : Brain Structures and Functions ... ﺩﺭ ... ﺻﺮ ﺍﻟﻨﺎ ﻋﺒﺪ WEEK 29-32 Slide 24 of 76 ﺩﺭ ﻋﺒ ﺪﺍ ﻟﻘﺎ ﺩﺭ ﺍﻟﻨﺎ ﺻﺮ ﻋﺒﺪ ﺍﻟﻘ ﺎ ﺩﺭ Common autoreceptors: – dopamine D2 receptor, – alpha 2a and alpha 2c adrenoreceptors, – 5-HT1A and 5-HT1B serotonin receptors – M2 and M4 muscarinic receptors, – H3 receptors. ﺻﺮ ﺍﻟﻨﺎ 12 An autoreceptor is a receptor located on the neuron (terminals, soma, and/or dendrites), and bind a specific ligand released by that same neuron. Most autoreceptors are inhibitory. Autoreceptors are generally G-protein coupled receptors. ﺻﺮ Neurotransmitters and hormone receptors ﺍ ﻟﻘﺎ 2/12/2024