PHAR 626 Introduction 2024 PDF

HOWDY! Physiology: Introduction Chapter 1-5 Part A Juan J. Bustamante, Ph.D. Assistant Professor Pharmaceutical Science Phone (361) 221-0643 Email: [email protected] Office: Room 223  PHAR 626 Physiology Course Coordinator and...

HOWDY! Physiology: Introduction Chapter 1-5 Part A Juan J. Bustamante, Ph.D. Assistant Professor Pharmaceutical Science Phone (361) 221-0643 Email: [email protected] Office: Room 223  PHAR 626 Physiology Course Coordinator and Instructor Course Meeting Time 1:10- 2:00 Mon, Tues, Wed, & Thursday Juan J. Bustamante, PhD. Office hours (in-person/zoom) Instructional Associate Professor Mon & Thurs, 2:00-3:00 PM Pharmaceutical Sciences and by appointment Office: 223 Phone: (361) 221-0643 Email: [email protected] Instructor Office hours (in-person/zoom) Zhenyu Li, Ph.D. by appointment Professor Pharmaceutical Sciences Office: 345 REYN Phone: 979.436.0264 Email: [email protected] Instructor Office hours (in-person/zoom) Sai Sudha Koka, Ph.D. by appointment Associate Professor Pharmaceutical Sciences Office: 304 Phone: 361.221.0758 Email: [email protected] PHAR-626 Human Physiology  PHAR- 672 Introduction to Patient Care Grades will be based on the performance from the following course activities: Homework/Assignments/Quizzes 72 points Exam I 72 points Exam II 72 points Exam III 72 points Exam IV 72 points Exam V 72 points Exam VI 72 points End of the Semester Assessment 100 points (comprehensive) Total: 604 points Note: Point allocation may subject to change at the discretion of course coordinators Make‐up Exams: In circumstances when a student must miss an exam, a student may make‐up an exam pending approval by the course coordinators prior to the exam date. The make‐up exam will be different from the original exam and most questions will require written responses. With an excused absence (as deemed by the Office of Student Affairs), the student may earn up to 100% of the total number of points on the make‐up exam. If the absence is unexcused, the student may earn up to 70% of the total number of points on the make‐up exam. There will be no make up exam offered for a second unexcused absence. ALL MAKE‐UP EXAMS WILL BE ADMINSTERED WITHIN 7 DAY OF YOUR RETURN.  Faculty Phi Lambda Sigma Peer Rho Chi Mentoring Tutoring Student Organization Mentoring Student Supplement Instructional (eg ‘Big Brother & Resources Leaders Littles’ Aspir2e Pre- Matriculation PharmD Program Peer Tutors Mentors Office of Student Success Exam 1 Material Learning Objectives Figure 1. 1 Slide 1 Levels of organization and the related fields of study PHYSIOLOGY ECOLOGY CELL BIOLOGY MOLECULAR CHEMISTRY BIOLOGY Organ Populations of Ecosystem of Atoms Molecules Cells Tissues Organs Organisms Biosphere systems one species different species © 2016 Pearson Education, Inc. Figure 1. 1 Levels of organization and the related fields of study Slide 4 Levels of organization and the related fields of study CELL BIOLOGY MOLECULAR CHEMISTRY BIOLOGY Atoms Molecules Cells Tissues © 2016 Pearson Education, Inc. Figure 1. 1 Levels of organization and the related fields of study Slide 5 Levels of organization and the related fields of study PHYSIOLOGY CELL BIOLOGY MOLECULAR CHEMISTRY BIOLOGY Organ Populations of Atoms Molecules Cells Tissues Organs Organisms one species systems © 2016 Pearson Education, Inc. Figure 1. 1 Levels of organization and the related fields of study Slide 6 Levels of organization and the related fields of study PHYSIOLOGY ECOLOGY CELL BIOLOGY MOLECULAR CHEMISTRY BIOLOGY Organ Populations of Ecosystem of Atoms Molecules Cells Tissues Organs Organisms Biosphere systems one species different species © 2016 Pearson Education, Inc. © 2016 Pearson Education, Inc.  Organ Systems in Review © 2016 Pearson Education, Inc.  Organ Systems in Review © 2016 Pearson Education, Inc. The lumen of a hollow organ such as the stomach is considered to be part of the ________ environment. A) internal B) external © 2016 Pearson Education, Inc. Figure 3.1a ANATOMICAL: The Body Cavities Levels of Organization: POSTERIOR ANTERIOR Body Cranial cavity Compartments Three major cavities Pleural sac Cranial Pericardial Thoracic cavity Thoracic sac Abdominopelvic Diaphragm Abdominal cavity Abdominopelvic cavity Pelvic cavity © 2016 Pearson Education, Inc. Figure 3.1a ANATOMICAL: The Body Cavities Levels of Organization: POSTERIOR ANTERIOR Body Cranial cavity Compartments Fluid-filled compartments Eyes Three major cavities Cerebrospinal fluid (CSF) Pleural sac Cranial Pericardial Thoracic cavity Thoracic sac Abdominopelvic Diaphragm Abdominal cavity Abdominopelvic cavity Pelvic cavity © 2016 Pearson Education, Inc. Figure 3.1a ANATOMICAL: The Body Cavities Levels of Organization: POSTERIOR ANTERIOR Body Cranial cavity Compartments Fluid-filled compartments Eyes Three major cavities Cerebrospinal fluid (CSF) Pleural sac Cranial Pericardial Thoracic cavity Thoracic sac Abdominopelvic Hollow organs Diaphragm Heart Lungs Blood vessels Abdominal cavity Intestines Abdominopelvic cavity Pelvic cavity © 2016 Pearson Education, Inc. Figure 3.1c Levels of Organization: Body Compartments Compartments Are Separated by Membranes Pericardial Tissue membranes Phospholipid bilayers membrane have many cells. create cell membranes. Cell Heart Loose connective tissue The pericardial sac is Seen magnified, the pericardial Each cell of the The cell membrane a tissue that surrounds membrane is a layer of flattened pericardial membrane is a phospholipid the heart. cells supported by connective has a cell membrane bilayer. tissue. surrounding it. Cell Membrane: Function Physical isolation Regulation of exchange with the environment Communication between the cell and its environment Structural support © 2016 Pearson Education, Inc. Figure 5.1a Body Fluid Compartments © 2016 Pearson Education, Inc. Figure 5.1b Body Fluid Compartments In the cell © 2016 Pearson Education, Inc. Figure 1.5 The body’s internal and external environments Keeping internal environment stable Interaction between o Outside world o Extracellular fluid o Intracellular fluid © 2016 Pearson Education, Inc. © 2016 Pearson Education, Inc. Figure 5.1d Body Fluid Compartments © 2016 Pearson Education, Inc.  Function Versus Process Function explains the “why” Process or mechanism describes the “how” – Mechanistic approach © 2016 Pearson Education, Inc.  Function Versus Process Red blood cell example – Why: Because cells need oxygen and red blood cells bring it to them. – How: Oxygen binds to hemoglobin molecules contained in the red blood cells. © 2016 Pearson Education, Inc. Homeostasis is the ability of the body to A. prevent the external environment from changing. B. prevent the internal environment from changing. C. quickly restore changed conditions to normal. D. ignore external stimuli to remain in a state of rest. E. prevent excessive blood loss.  Homeostasis Regulation of the body’s internal environment Figure 1.4 © 2016 Pearson Education, Inc. Figure 1.3b Mapping Example © 2016 Pearson Education, Inc.