2009PHM Quiz 1 in 2023-1.pdf

04/08/2023, 07:26 2009PHM Quiz 1 in 2023 NAME : CLASS : 2009PHM Quiz 1 in 2023 16 Questions DATE : 1. Which of the following are NON-modifiable risk factors? A Age B Waist circumference C Diabetes D Familial hypercholesterolaemia E Salt intake 2. How are you going in T2 so far? A...

04/08/2023, 07:26 2009PHM Quiz 1 in 2023 NAME : CLASS : 2009PHM Quiz 1 in 2023 16 Questions DATE : 1. Which of the following are NON-modifiable risk factors? A Age B Waist circumference C Diabetes D Familial hypercholesterolaemia E Salt intake 2. How are you going in T2 so far? A I'm still adjusting B Average C Excellent D I'm a bit worried E I'm OK 3. Which of the following is INCORRECT about hypertension drugs? A thiazides can be used but only at low doses B β-blockers are recommended as first-line therapy C ACE inhibitors and ARBs have different mechanisms of action D The efficacies of anti-hypertensive drugs are the same E Always check to see if the patient has any co-morbidities 4. Which of the following drugs directly stops the production of Angiotensin II? A enalopril B perindopril C ramipril D amyl nitrate E candesartan 5. Which of the following anti-hypertensive drugs is an α2-agonist that stops the release of noradrenaline? A irbesartan B clonidine C ethacrynic acid D prazosin E methylxanthine https://quizizz.com/print/quiz/64c0f8fa635c9d0007b25117 ? 1/3 04/08/2023, 07:26 2009PHM Quiz 1 in 2023 6. Check all the following that are features of the dihydropyridines class of antihypertension drugs. A Acts on cardiac tissue B Used in first-line treatment of hypertension C Are metabolised by the CYP3A4 liver enzyme D Acts on vascular smooth muscle cells E Include drugs such as diltiazem and verapamil 7. Check any of the following that are drugs used in hypertensive emergencies. A Frusemide B Enalopril C AT1 receptor blocker D Sodium nitroprusside E Hydralazine 8. To reduce platelet aggregation, the mediator that stops being produced when aspirin blocks the COX (cyclooxygenase) enzyme is A prostaglandins B leukotrienes C arachidonic acid D thromboxane A2 E lipids 9. Why do platelets need to have glycoprotein IIb/IIIa receptors on their surface? A To allow for the binding of COX-1 enzyme B tightly to the surface It helps them produce ADP so it can synthesise more platelets C To inhibit thrombin It generates binding surfaces for collagen on the vascular endothelium E It permits fibrinogen to attach and make crosslinks between platelets 10. The correct spelling of the antiplatelet drug that acts as a PDE inhibitor is https://quizizz.com/print/quiz/64c0f8fa635c9d0007b25117 D 2/3 04/08/2023, 07:26 2009PHM Quiz 1 in 2023 11. From the following drugs, select the ones that are P2Y12 receptor antagonists A prasugrel B ticagrelor C clopidogrel D ADP E warfarin 12. For the GP IIb/IIIa receptor inhibitors, which of the following drugs mimics the structure of fibrinogen so it cannot form crosslinks between platelets? A abciximab B tirofiban C eptifibatide D aspirin E warfarin 13. Are you ready for some DOUBLE POINTS questions? A Yes B No C A little bit D Alright, bring it on... 14. Drugs that decrease cholesterol levels in liver cells also then cause which "bonus" secondary outcome? A Increased presence of LDL receptors B Stimulation of chylomicrons C Greater transport of LDL out of cells D Destruction of LDL receptor genes E Synthesis of liver VLDL 15. What chemical reaction would improve the hydrophilicity of a statin? A glucuronidation B protection of the pharmacophore C attachment to a chloride ion D hydrolysis of the lactone E aromatic group addition 16. What do the bile acid-binding resins ultimately prevent? A excretion of insoluble complexes B enzymatic breakdown C bile acid recycling via the liver D lowered HDL levels E lipolysis https://quizizz.com/print/quiz/64c0f8fa635c9d0007b25117 3/3