Non-Modifiable Risk Factors
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Questions and Answers

Which of the following are NON-modifiable risk factors for hypertension?

  • Familial hypercholesterolaemia (correct)
  • Waist circumference
  • Diabetes
  • Age

    • How are you going in T2 so far?

  • I'm a bit worried
  • I'm still adjusting
  • Excellent (correct)
  • Average

    • Which of the following is INCORRECT about hypertension drugs?

  • Thiazides can be used but only at low doses
  • ACE inhibitors and ARBs have different mechanisms of action
  • β-blockers are recommended as first-line therapy (correct)
  • The efficacies of anti-hypertensive drugs are the same

    • Which of the following drugs directly stops the production of Angiotensin II?

    <p>Enalopril</p> Signup and view all the answers

    Which of the following anti-hypertensive drugs is an α2-agonist that stops the release of noradrenaline?

    <p>Clonidine</p> Signup and view all the answers

    Check all the following that are features of the dihydropyridines class of antihypertension drugs.

    <p>Acts on vascular smooth muscle cells</p> Signup and view all the answers

    Check any of the following that are drugs used in hypertensive emergencies.

    <p>Sodium nitroprusside</p> Signup and view all the answers

    Which of the following is the mediator that stops being produced when aspirin blocks the COX (cyclooxygenase) enzyme?

    <p>Thromboxane A2</p> Signup and view all the answers

    Why do platelets need to have glycoprotein IIb/IIIa receptors on their surface?

    <p>To permit fibrinogen to attach and make crosslinks between platelets</p> Signup and view all the answers

    Which of the following drugs acts as a PDE inhibitor and is used as an antiplatelet drug?

    <p>Ticagrelor</p> Signup and view all the answers

    Which of the following drugs are P2Y12 receptor antagonists?

    <p>Clopidogrel</p> Signup and view all the answers

    Which of the following drugs mimics the structure of fibrinogen and prevents crosslinks between platelets?

    <p>Abciximab</p> Signup and view all the answers

    What "bonus" secondary outcome do drugs that decrease cholesterol levels in liver cells cause?

    <p>Greater transport of LDL out of cells</p> Signup and view all the answers

    Which chemical reaction would improve the hydrophilicity of a statin?

    <p>Glucuronidation</p> Signup and view all the answers

    What do bile acid-binding resins ultimately prevent?

    <p>Bile acid recycling via the liver</p> Signup and view all the answers

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