Non-Modifiable Risk Factors

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Questions and Answers

Which of the following are NON-modifiable risk factors for hypertension?

  • Familial hypercholesterolaemia (correct)
  • Waist circumference
  • Diabetes
  • Age

How are you going in T2 so far?

  • I'm a bit worried
  • I'm still adjusting
  • Excellent (correct)
  • Average

Which of the following is INCORRECT about hypertension drugs?

  • Thiazides can be used but only at low doses
  • ACE inhibitors and ARBs have different mechanisms of action
  • β-blockers are recommended as first-line therapy (correct)
  • The efficacies of anti-hypertensive drugs are the same

Which of the following drugs directly stops the production of Angiotensin II?

<p>Enalopril (D)</p> Signup and view all the answers

Which of the following anti-hypertensive drugs is an α2-agonist that stops the release of noradrenaline?

<p>Clonidine (D)</p> Signup and view all the answers

Check all the following that are features of the dihydropyridines class of antihypertension drugs.

<p>Acts on vascular smooth muscle cells (B)</p> Signup and view all the answers

Check any of the following that are drugs used in hypertensive emergencies.

<p>Sodium nitroprusside (C)</p> Signup and view all the answers

Which of the following is the mediator that stops being produced when aspirin blocks the COX (cyclooxygenase) enzyme?

<p>Thromboxane A2 (D)</p> Signup and view all the answers

Why do platelets need to have glycoprotein IIb/IIIa receptors on their surface?

<p>To permit fibrinogen to attach and make crosslinks between platelets (B)</p> Signup and view all the answers

Which of the following drugs acts as a PDE inhibitor and is used as an antiplatelet drug?

<p>Ticagrelor (D)</p> Signup and view all the answers

Which of the following drugs are P2Y12 receptor antagonists?

<p>Clopidogrel (C)</p> Signup and view all the answers

Which of the following drugs mimics the structure of fibrinogen and prevents crosslinks between platelets?

<p>Abciximab (B)</p> Signup and view all the answers

What "bonus" secondary outcome do drugs that decrease cholesterol levels in liver cells cause?

<p>Greater transport of LDL out of cells (C)</p> Signup and view all the answers

Which chemical reaction would improve the hydrophilicity of a statin?

<p>Glucuronidation (D)</p> Signup and view all the answers

What do bile acid-binding resins ultimately prevent?

<p>Bile acid recycling via the liver (D)</p> Signup and view all the answers

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